WormBase Tree Display for Gene: WBGene00013895

WBGene00013895 SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 1
    Name: Sequence_name: ZC434.9
      Molecular_name (15)
      Other_name: CELE_ZC434.9 Accession_evidence: NDB BX284601
      Public_name: ZC434.9
    DB_info: Database: AceView gene 1K935
        WormQTL gene WBGene00013895
        WormFlux gene WBGene00013895
        NDB locus_tag CELE_ZC434.9
        Panther gene CAEEL|WormBase=WBGene00013895|UniProtKB=G3MU29
          family PTHR11705
        NCBI gene 172908
        RefSeq protein NM_001264428.4
            NM_001026681.4
            NM_001026680.7
            NM_001264429.3
            NM_001264427.2
        TrEMBL UniProtAcc Q23318
            G3MU28
            G3MU30
            G3MU29
            Q7JLE3
        UniProt_GCRP UniProtAcc G3MU29
        OMIM gene 609562
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (49)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (45)
    Paralog: WBGene00008521 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00011235 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012168 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00021213 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00021645 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020281 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020283 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00021984 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004747 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Is an ortholog of human CPA6 (carboxypeptidase A6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0060752 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17245)
      DOID:0111308 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17245)
  Molecular_info: Corresponding_CDS: ZC434.9a
      ZC434.9b
      ZC434.9c
      ZC434.9d
      ZC434.9e
    Corresponding_CDS_history: ZC434.9a:wp192
      ZC434.9b:wp192
    Corresponding_transcript: ZC434.9a.1
      ZC434.9b.1
      ZC434.9c.1
      ZC434.9d.1
      ZC434.9e.1
    Other_sequence (32)
    Associated_feature (6)
  Experimental_info: RNAi_result: WBRNAi00004891 Inferred_automatically: RNAi_primary
      WBRNAi00038061 Inferred_automatically: RNAi_primary
      WBRNAi00091331 Inferred_automatically: RNAi_primary
      WBRNAi00103640 Inferred_automatically: RNAi_primary
      WBRNAi00058917 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1015555
      Expr1036217
      Expr1162357
      Expr2008631
      Expr2026866
    Drives_construct: WBCnstr00029464
    Construct_product: WBCnstr00029464
    Microarray_results (26)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00043945:MeHg_downregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Spermatogenic
      WBPaper00045774:clk-1_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049290:rsks-1(sv31)_upregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:hypodermis_enriched
      WBPaper00050990:hypodermis_expressed
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056039:ptrn-1(tm5597)_downregulated
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059895:wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060224:atf-6(ok551)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:hypoxia_downregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:ant_arc_V
      WBPaper00061340:AVB
      WBPaper00061340:RIB
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:R12E2.14_75-R12E2.15
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
      WBPaper00061651:RIB_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062456:doxycycline_downregulated_N2_protein
      WBPaper00062456:doxycycline_upregulated_CB4856_transcript
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_downregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064850:glh-1(sam65)_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065623:100
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:21_0
      WBPaper00065841:21_1
      WBPaper00065841:121_0
      WBPaper00065841:144_0
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_transcript
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066085:sin-3(tm1276)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4386_cluster_2_3
      cgc4489_group_4
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00027342:alpha-Synuclein(A53T)_upregulated
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00034739:N2moreDR1350
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035891:zip-2(RNAi)_downregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_C
      WBPaper00037695:WC_5-day
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00045960:L1-L4-lethargus_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_UV_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:Cluster_C
    Interaction: WBInteraction000123326
      WBInteraction000123898
      WBInteraction000123902
      WBInteraction000123926
      WBInteraction000123932
      WBInteraction000293568
      WBInteraction000519754
  Map_info: Positive: Positive_clone: ZC434 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 4.93239
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene