Y57G11C.3 encodes the C. elegans 6-phosphogluconolactonase (6PGL) ortholog; by homology, the product of Y57G11C.3 is predicted to catalyze the second reaction of the oxidative branch of the pentose-phosphate pathway in which 6-phosphogluconolactone is converted to 6-phosphogluconate.
Predicted to enable 6-phosphogluconolactonase activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Located in nucleus. Expressed in germ cell. Is an ortholog of human PGLS (6-phosphogluconolactonase).