WormBase Tree Display for Gene: WBGene00011953

WBGene00011953 SMap: S_parent: Sequence: T23F11
  Identity: Version: 2
    Name: CGC_name: ppm-2 Person_evidence: WBPerson4866
      Sequence_name: T23F11.1
      Molecular_name: T23F11.1
        T23F11.1.1
        CE24009
      Other_name: CELE_T23F11.1 Accession_evidence: NDB BX284603
      Public_name: ppm-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Jun 2012 17:01:34 WBPerson2970 Name_change: CGC_name: ppm-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ppm
    Allele (36)
    Strain: WBStrain00037117
    RNASeq_FPKM (74)
    GO_annotation (18)
    Ortholog (26)
    Paralog: WBGene00001412 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006460 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009354 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018362 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00022832 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016580 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00021856 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00006524 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Enables ubiquitin protein ligase binding activity. Involved in negative regulation of axon extension and positive regulation of synapse assembly. Located in presynaptic active zone. Expressed in mechanosensory neurons; motor neurons; muscle cell; nerve ring neurons; and pharynx. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T23F11.1
    Corresponding_transcript: T23F11.1.1
    Other_sequence (55)
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00019083 Inferred_automatically: RNAi_primary
      WBRNAi00035867 Inferred_automatically: RNAi_primary
      WBRNAi00068039 Inferred_automatically: RNAi_primary
      WBRNAi00000870 Inferred_automatically: RNAi_primary
      WBRNAi00005055 Inferred_automatically: RNAi_primary
      WBRNAi00053939 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11790
      Expr11791
      Expr1025135
      Expr1035277
      Expr1157484
      Expr2015020
      Expr2033255
    Drives_construct: WBCnstr00019428
      WBCnstr00030256
    Construct_product: WBCnstr00019391
      WBCnstr00030256
    Microarray_results (25)
    Expression_cluster: WBPaper00032425:up_in_lin-35
      WBPaper00032425:up_in_rde-4
      WBPaper00032528:L3_enriched
      WBPaper00034761:hlh-30_downregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042477:prp-8(RNAi)_downregulated_RNAseq
      WBPaper00044736:flat_dev_expression
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(+)
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055482:Tunicamycin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061527:dld-1-skn-1_16701
      WBPaper00061527:ldb-1_2877-scd-1_3086
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00063930:BRD-1_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00066062:xrep-4(lax137)_upregulated
      cgc4489_group_11
      WBPaper00025032:cluster_76
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00034739:N2moreDR1350
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035504:daf-2(e1370)_upregulated
      WBPaper00037695:WC_5-day
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00055899:nitroguanidine_regulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (98)
  Map_info: Map: III Position: -2.95174
    Positive: Positive_clone: T23F11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (7)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene