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WormBase Tree Display for Gene: WBGene00010230

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Name Class

WBGene00010230SMapS_parentSequenceF58A4
IdentityVersion2
NameCGC_namerpac-19Person_evidenceWBPerson10054
Sequence_nameF58A4.9
Molecular_nameF58A4.9
F58A4.9.1
CE00225
Other_nameCELE_F58A4.9Accession_evidenceNDBBX284603
Public_namerpac-19
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
228 Sep 2012 14:29:00WBPerson2970Name_changeCGC_namerpac-19
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrpac
AlleleWBVar01500260
WBVar00405717
WBVar01499774
WBVar01723199
WBVar01332159
WBVar00092985
WBVar00851574
WBVar00851575
WBVar01645909
StrainWBStrain00036516
RNASeq_FPKM (74)
GO_annotation (11)
Contained_in_operonCEOP3608
Ortholog (29)
ParalogWBGene00012187Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I and transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Used to study obesity. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 2. Is an ortholog of human POLR1D (RNA polymerase I and III subunit D).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00061889
Curator_confirmedWBPerson324
Date_last_updated28 Jun 2022 00:00:00
Potential_modelDOID:0080790Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:20422)
Models_disease_in_annotationWBDOannot00001261
Molecular_infoCorresponding_CDSF58A4.9
Corresponding_transcriptF58A4.9.1
Other_sequence (27)
Associated_featureWBsf651391
WBsf993736
Experimental_infoRNAi_result (26)
Expr_patternExpr1014907
Expr1034461
Expr1152674
Expr2015417
Expr2033652
Drives_constructWBCnstr00031569
Construct_productWBCnstr00031569
Microarray_results (19)
Expression_clusterWBPaper00028451:Low_abundance_spermatogenesis_enriched
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032097:CGH-1-associated-mRNA
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_embryo_enriched
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:bodywall-muscle_larva_enriched
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044760:germline_specific
WBPaper00045316:prg-1_downregulated_L1
WBPaper00045316:prg-1_downregulated_L2
WBPaper00045316:prg-1_downregulated_L3
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00048910:mRNA-interacting_protein
WBPaper00048926:miaserin_upregulated_adult-day5
WBPaper00048988:neuron_expressed
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:body-wall-muscle_nucleus_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_nucleus_expressed
WBPaper00051245:nucleus_specific
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053599:mitosis_vs_meiosis_upregulated
WBPaper00053599:oocyte_vs_mitosis_upregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00054758:alg-1(gk204)_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055482:pmt-2(RNAi)_downregulated
WBPaper00055648:germline_expressed
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00059254:CSR-1_interacting
WBPaper00059254:PRG-1_interacting
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059605:MUT-16_interacting
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061340:M_cell
WBPaper00061341:28C_48h_downregulated
WBPaper00061479:HDA-1_interacting_protein
WBPaper00061527:mrpl-54-lbp-4
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062293:isp-1(qm150)_downregulated
WBPaper00062498:PPM-1.D_interacting
WBPaper00062590:Aging_upregulated_neuron
WBPaper00063930:BRD-1_interacting
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064130:Beta-Amyloid_downregulated_protein
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00064716:paraquat_upregulated
WBPaper00064933:E.coli-binding_secret_protein
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4386_cluster_4_4
cgc4489_group_2
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00034757:down_by_oxidative_stress
WBPaper00036130:mir-243_down_regulated
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00038231:Cry5B_2-fold_downregulated
WBPaper00039866:ClassComp_daf-19_downregulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_aging
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00048637:lin-35(n745)_starvation_downregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:Cluster_F
[cgc6390]:oogenesis-enriched
Interaction (186)
Map_info (3)
ReferenceWBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00061889
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene