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WormBase Tree Display for Gene: WBGene00009051

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Name Class

WBGene00009051SMapS_parentSequenceF22D6
IdentityVersion3
NameCGC_namenduf-6
Sequence_nameF22D6.4
Molecular_nameF22D6.4
F22D6.4.1
CE05685
Other_namendus-6Person_evidenceWBPerson555
CELE_F22D6.4Accession_evidenceNDBBX284601
Public_namenduf-6
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
226 Feb 2008 13:57:13WBPerson2970Name_changeCGC_namenduf-6
316 Jan 2023 18:37:21WBPerson51134Name_changeOther_namendus-6
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnduf
AlleleWBVar02154164
WBVar01499786
WBVar01499054
WBVar00297993
WBVar00647630
WBVar00647631
WBVar00337546
WBVar01498959
StrainWBStrain00049344
RNASeq_FPKM (73)
GO_annotation (12)
Ortholog (36)
Structured_descriptionConcise_descriptionF22D6.4 encodes an NDUFS6/13 kDa subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I); F22D6.4 is required for oxidative phosphorylation and for resistance to volatile anesthetics.Paper_evidenceWBPaper00005928
WBPaper00028429
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated13 Dec 2006 00:00:00
Automated_descriptionInvolved in mitochondrial electron transport, NADH to ubiquinone and response to xenobiotic stimulus. Located in mitochondrion. Human ortholog(s) of this gene implicated in cervical cancer and nuclear type mitochondrial complex I deficiency 9. Is an ortholog of human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112073Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7713)
DOID:4362Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7713)
Molecular_infoCorresponding_CDSF22D6.4
Corresponding_transcriptF22D6.4.1
Other_sequence (40)
Associated_featureWBsf643423
WBsf981038
WBsf217941
WBsf217942
Experimental_infoRNAi_result (17)
Expr_patternExpr1018697
Expr1033947
Expr1149241
Expr2013934
Expr2032173
Drives_constructWBCnstr00032497
Construct_productWBCnstr00032497
Microarray_results (20)
Expression_clusterWBPaper00028451:Low_abundance_spermatogenesis_enriched
WBPaper00032528:L3_enriched
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037086:biotin_regulated
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038118:aak-2(gt33)_downregulated
WBPaper00040221:DAF-12_target_ALF4
WBPaper00040965:lipid-droplet_associated_protein
WBPaper00044128:daf-2(e1370)_upregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045521:Gender_Neutral
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051039:germline_enriched
WBPaper00053302:stavudine_24h_regulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055827:pfd-6(gk493446)_upregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_protein
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00059763:neuron_expressed
WBPaper00059987:Wounding_upregulated
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061527:C47G2.3-C47B2.9
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00064005:starvation_downregulated_N2_mRNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064130:Beta-Amyloid_downregulated_protein
WBPaper00064992:Capsaicin_downregulated
WBPaper00065258:anchor-cell_enriched
cgc4386_cluster_3_5
cgc4489_group_3
WBPaper00025032:cluster_152
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00035504:daf-2(e1370)_upregulated
WBPaper00036286:Pattern_G
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00049538:atfs-1(et18)_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(186_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(23_min)
[cgc5767]:expression_class_ME
Interaction (81)
Map_info (3)
ReferenceWBPaper00005928
WBPaper00028429
WBPaper00038491
WBPaper00055090
WBPaper00062388
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene