| WBGene00006407 | Evidence | CGC_data_submission |
|---|
| SMap | S_parent | Sequence | CHROMOSOME_I |
| Identity | Version | 4 |
| | Name | CGC_name | lim-9 | Person_evidence | WBPerson54 |
| | | | | | WBPerson505 |
| | | | | | WBPerson545 |
| | | Sequence_name | F25H5.1 |
| | | Molecular_name (24) |
| | | Other_name (2) |
| | | Public_name | lim-9 |
| | DB_info | Database | AceView | gene | 1J758 |
| | | | WormQTL | gene | WBGene00006407 |
| | | | WormFlux | gene | WBGene00006407 |
| | | | NDB | locus_tag | CELE_F25H5.1 |
| | | | Panther | gene | CAEEL|WormBase=F25H5.1i|UniProtKB=A0A0K3AQM0 |
| | | | | family | PTHR24205 |
| | | | NCBI | gene | 3565712 |
| | | | RefSeq | protein | NM_001377616.3 |
| | | | | | NM_001026238.6 |
| | | | | | NM_001377617.3 |
| | | | | | NM_001026237.7 |
| | | | | | NM_001313465.3 |
| | | | | | NM_001313491.3 |
| | | | | | NM_001030057.5 |
| | | | | | NM_001313466.5 |
| | | | TREEFAM | TREEFAM_ID | TF321684 |
| | | | TrEMBL | UniProtAcc | G5EDJ5 |
| | | | | | A0A0K3AQM0 |
| | | | | | Q3S1I9 |
| | | | | | A0A0K3AQP4 |
| | | | | | O17833 |
| | | | | | G5EEA4 |
| | | | | | A0A0K3ATK8 |
| | | | | | G5EF39 |
| | | | UniProt_GCRP | UniProtAcc | A0A0K3AQM0 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | | | 2 | 02 Feb 2007 10:20:45 | WBPerson2970 | Name_change | CGC_name | lim-9 |
| | | | | | | | Other_name | tag-15 |
| | | | 3 | 10 Jun 2014 12:12:12 | WBPerson1983 | Event | Acquires_merge | WBGene00008108 |
| | | | 4 | 13 Nov 2014 15:02:41 | WBPerson4025 | Event | Acquires_merge | WBGene00008109 |
| | | Acquires_merge | WBGene00008108 |
| | | | WBGene00008109 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | lim |
| | Allele (432) |
| | Strain | WBStrain00035585 |
| | | WBStrain00035699 |
| | In_cluster | conserved_miRNA_siRNA_cluster |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00000569 |
| | | 00000570 |
| | | 00000571 |
| | | 00000572 |
| | | 00000573 |
| | | 00014123 |
| | | 00014124 |
| | | 00014125 |
| | | 00014126 |
| | | 00114034 |
| | Ortholog (55) |
| | Structured_description | Concise_description | lim-9 encodes a protein containing one PET domain and six LIM domains and is orthologous to Drosophila LIMPET and vertebrate FHL2; in vitro binding and yeast two-hybrid assays indicate that LIM-9 physically interacts with UNC-96 and UNC-97 and thus, is likely a component of a protein complex that links muscle focal adhesions to thick filaments; LIM-9 also enables Wnt-directed planar cell polarity and is required for the fully asymmetrical division of B.a versus B.p cells, though this requirement is quantitatively weak; a lim-9::gfp promoter fusion is expressed in pharyngeal and body wall muscles, as well as in some neuronal processes, vulva, spermathecae, anal sphincter and depressor muscles, gonadal sheath, and the excretory canal; staining with LIM-9 antibodies reveals that in body wall muscle LIM-9 localizes, at least partially, to M-lines, around which myosin thick filaments are organized. | Paper_evidence | WBPaper00027345 |
| | | | | | WBPaper00030924 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | | WBPerson567 |
| | | | | Date_last_updated | 27 Feb 2009 00:00:00 |
| | | Automated_description | Enables protein domain specific binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in M band. Expressed in several structures, including body wall musculature; excretory canal; non-striated muscle; spermatheca; and vulva. Is an ortholog of human FHL2 (four and a half LIM domains 2). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F25H5.1b |
| | | F25H5.1c |
| | | F25H5.1d |
| | | F25H5.1e |
| | | F25H5.1f |
| | | F25H5.1g |
| | | F25H5.1h |
| | | F25H5.1i |
| | Corresponding_CDS_history | F25H5.1a:wp136 |
| | | F25H5.1a:wp275 |
| | | F25H5.1b:wp136 |
| | | F25H5.1b:wp246 |
| | | F25H5.1c:wp246 |
| | | F25H5.1d:wp246 |
| | | F25H5.1f:wp183 |
| | Corresponding_transcript | F25H5.1b.1 |
| | | F25H5.1c.1 |
| | | F25H5.1d.1 |
| | | F25H5.1e.1 |
| | | F25H5.1f.1 |
| | | F25H5.1g.1 |
| | | F25H5.1h.1 |
| | | F25H5.1i.1 |
| | Other_sequence (62) |
| | Associated_feature (44) |
| | Transcription_factor | WBTranscriptionFactor000581 |
| Experimental_info | RNAi_result (14) |
| | Expr_pattern | Expr8313 |
| | | Expr8316 |
| | | Expr8552 |
| | | Expr1025302 |
| | | Expr1029193 |
| | | Expr1032599 |
| | | Expr1146521 |
| | | Expr1149460 |
| | | Expr2013155 |
| | | Expr2031387 |
| | Drives_construct | WBCnstr00013257 |
| | Antibody | WBAntibody00001285 |
| | Microarray_results (81) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00032425:up_in_lin-35 |
| | | WBPaper00032425:up_in_rde-4 |
| | | WBPaper00032425:up_in_zfp-1 |
| | | WBPaper00033065:clk-1(qm30)_upregulated |
| | | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00033065:isp-1-1(qm150)_upregulated |
| | | WBPaper00033070:Rhine_upregulated |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037055:DAF-16_binding_DNA |
| | | WBPaper00037946:LIN-39_interacting |
| | | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:A-class-motor-neurons_larva_enriched |
| | | WBPaper00037950:all-neurons_L1-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:bodywall-muscle_L1-larva_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:excretory-cell_L2-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_embryo_enriched |
| | | WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:germline-precursors_blastula-embryo_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq |
| | | WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray |
| | | WBPaper00042561:smgl-1(RNAi)_upregulated |
| | | WBPaper00042561:smgl-2(RNAi)_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045390:tunicamycin_downregulated |
| | | WBPaper00045521:Spermatogenic |
| | | WBPaper00045774:clk-1_upregulated |
| | | WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h |
| | | WBPaper00046509:htz-1(ok3099)_downregulated |
| | | WBPaper00047132:glp-1(ts)-25C_upregulated |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:neuron_enriched |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049217:TCER-1_downregulated |
| | | WBPaper00049377:MWCNT_upregulated |
| | | WBPaper00049495:starvation-refeeding_regulated |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated |
| | | WBPaper00050053:muscle_enriched_Day4 |
| | | WBPaper00050182:lmn-1(L535P)_upregulated |
| | | WBPaper00050468:hlh-30-dependent_Cry5B_regulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C |
| | | WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00051039:ash-2(RNAi)_regulated_intestine |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:body-wall-muscle_nucleus_expressed |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:epidermis_nucleus_expressed |
| | | WBPaper00051245:nucleus_specific |
| | | WBPaper00051555:atm-1(gk186)_regulated_protein |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053302:zidovudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053388:dauer_regulated_Cluster1 |
| | | WBPaper00053599:oocyte_vs_mitosis_downregulated |
| | | WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated |
| | | WBPaper00053810:nuo-6(qm200)_upregulated |
| | | WBPaper00053814:15C_downregulated_PY79 |
| | | WBPaper00055354:eat-2(ad1116)_downregulated |
| | | WBPaper00055354:Psora-Allantoin_downregulated |
| | | WBPaper00055354:Psora_downregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Metformin_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_downregulated |
| | | WBPaper00055354:Rifampicin_downregulated |
| | | WBPaper00055482:pmt-2(RNAi)_upregulated |
| | | WBPaper00055482:Tunicamycin_downregulated |
| | | WBPaper00055565:AVK_enriched |
| | | WBPaper00055827:pfd-6(gk493446)_downregulated |
| | | WBPaper00055969:electromagnetic-field_downregulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056139:soil-microbiota_downregulated |
| | | WBPaper00056139:soil-microbiota_upregulated |
| | | WBPaper00056275:P.aeruginosa_upregulated |
| | | WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent |
| | | WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056471:S.aureus-4h_upregulated_N2 |
| | | WBPaper00056826:hmc_biased |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated |
| | | WBPaper00057288:Cold_upregulated_transcript |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058725:sftb-1(cer6)_upregulated |
| | | WBPaper00058725:sftb-1(cer39)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA |
| | | WBPaper00059421:daf-1(m40)_upregulated |
| | | WBPaper00059421:daf-3(mgDf90)_downregulated |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059605:MUT-16_interacting |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059763:neuron_expressed |
| | | WBPaper00060014:set-2(zr2012)_upregulated |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_N2 |
| | | WBPaper00060459:bcat-1(RNAi)_upregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00060871:M.humicola-extract_4h_regulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:AIA |
| | | WBPaper00061340:AIM |
| | | WBPaper00061340:AVB |
| | | WBPaper00061340:DA |
| | | WBPaper00061340:DA_DB |
| | | WBPaper00061340:DB |
| | | WBPaper00061340:DVA |
| | | WBPaper00061340:hmc |
| | | WBPaper00061340:I5 |
| | | WBPaper00061340:MC |
| | | WBPaper00061340:mu_sph |
| | | WBPaper00061340:OLQ |
| | | WBPaper00061340:RIS |
| | | WBPaper00061340:SIB |
| | | WBPaper00061340:SMB |
| | | WBPaper00061466:nath-10(icb102)_downregulated |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:cdc-42_17192-rab-5_18073 |
| | | WBPaper00061527:kin-29_2839-unc-9_3883 |
| | | WBPaper00061527:srj-21-srh-32 |
| | | WBPaper00061527:tub-2_4713-daf-2_5288 |
| | | WBPaper00061651:DB_enriched |
| | | WBPaper00061651:DVA_enriched |
| | | WBPaper00061651:I3_enriched |
| | | WBPaper00061651:M2_enriched |
| | | WBPaper00061651:MC_enriched |
| | | WBPaper00061651:PDA_enriched |
| | | WBPaper00061651:PLN_enriched |
| | | WBPaper00061651:RME_DV_enriched |
| | | WBPaper00061651:SAA_enriched |
| | | WBPaper00061651:SIA_enriched |
| | | WBPaper00061651:SIB_enriched |
| | | WBPaper00061651:SMB_enriched |
| | | WBPaper00061651:URA_enriched |
| | | WBPaper00061651:URY_enriched |
| | | WBPaper00061651:VA12_enriched |
| | | WBPaper00061651:VC_4_5_enriched |
| | | WBPaper00062103:neuron_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062193:skn-1(RNAi)_downregulated |
| | | WBPaper00062325:etr-1(lq61)_upregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064494:postdauer_upregulated_AWA |
| | | WBPaper00064716:paraquat_downregulated |
| | | WBPaper00064727:daf-2(e1370)_upregulated |
| | | WBPaper00064939:vit-5(RNAi)_upregulated |
| | | WBPaper00064992:Capsaicin_downregulated |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065373:Cisplatin_downregulated_WT |
| | | WBPaper00065841:56_0 |
| | | WBPaper00065841:109_0 |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | WBPaper00066085:sin-3(syb2172)_upregulated |
| | | WBPaper00066232:ash-2(RNAi)_downregulated_WT |
| | | cgc4489_group_12 |
| | | WBPaper00025032:cluster_18 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:Resveratrol_regulated_daf-16 |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00029437:dcr-1_upregulated |
| | | WBPaper00030985:Erwinia_carotovora_upregulated |
| | | WBPaper00031003:24hr_muscle_enriched |
| | | WBPaper00031003:hlh_1_enriched |
| | | WBPaper00031003:total_muscle_enriched |
| | | WBPaper00031252:AIN-1_IP_enriched |
| | | WBPaper00031532:Larva_Pan_Neuronal_Depleted |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00031832:slr-2_regulated |
| | | WBPaper00034661:AgNPs_downregulated |
| | | WBPaper00034739:N2lessDR1350 |
| | | WBPaper00034739:N2moreDR1350 |
| | | WBPaper00035873:dpy-9_regulated |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated |
| | | WBPaper00037695:WC_5-day |
| | | WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up |
| | | WBPaper00040210:Chlorpyrifos_24C_regulated |
| | | WBPaper00040858:eQTL_age_regulated_developing |
| | | WBPaper00040858:eQTL_regulated_developing |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00040963:TA200_up |
| | | WBPaper00040963:TA300_up |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_3h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_3h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_48h |
| | | WBPaper00042258:DA1877_upregulated_GravidAdult |
| | | WBPaper00042331:a-SWCNTs_downregulated |
| | | WBPaper00045960:L1-L4-lethargus_upregulated |
| | | WBPaper00045960:L4-lethargus_upregulated |
| | | WBPaper00046548:dafachronic-acid_downregulated |
| | | WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated |
| | | WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated |
| | | WBPaper00048989:N2_allantoin_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | Interaction (40) |
| Map_info | Map | I | Position | 3.6557 | Error | 0.004609 |
| | Positive | Positive_clone | F25H5 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference (13) |
| Remark | Gene name created from parsing 'genotype' field from CGC strain information | CGC_data_submission |
| | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| | [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag. |
| Method | Gene |
