WormBase Tree Display for Gene: WBGene00003834

WBGene00003834 SMap: S_parent: Sequence: C15H11
  Identity: Version: 1
    Name: CGC_name: nxf-1
      Sequence_name: C15H11.3
      Molecular_name: C15H11.3
        C15H11.3.1
        CE42865
      Other_name: nfx-1 Paper_evidence: WBPaper00041879
        CELE_C15H11.3 Accession_evidence: NDB BX284605
      Public_name: nxf-1
    DB_info: Database: AceView gene 5O892
        WormQTL gene WBGene00003834
        WormFlux gene WBGene00003834
        NDB locus_tag CELE_C15H11.3
        Panther gene CAEEL|WormBase=WBGene00003834|UniProtKB=Q9XVS7
          family PTHR10662
        NCBI gene 191736
        RefSeq protein NM_001136408.4
        TrEMBL UniProtAcc B5BM32
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nxf
    Allele (69)
    Possibly_affected_by: WBVar02158628
      WBVar02158629
      WBVar02158630
    Strain (6)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (50)
    Paralog: WBGene00003835 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: nxf-1 encodes a homolog of human TAP protein, a member of the NXF family of shuttling transport receptors for nuclear export of mRNA; binds RNA directly and its function has been shown to be conserved with the NXF family. Paper_evidence: WBPaper00004473
            WBPaper00005959
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable RNA binding activity. Predicted to be involved in mRNA export from nucleus. Located in nuclear envelope; nucleolus; and nucleoplasm. Part of nuclear pore. Is an ortholog of human NXF1 (nuclear RNA export factor 1); NXF2 (nuclear RNA export factor 2); and NXF2B (nuclear RNA export factor 2B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C15H11.3
    Corresponding_CDS_history: C15H11.3a:wp267
    Corresponding_transcript: C15H11.3.1
    Other_sequence: CBC01576_1
    Associated_feature (13)
  Experimental_info: RNAi_result: WBRNAi00040618 Inferred_automatically: RNAi_primary
      WBRNAi00028925 Inferred_automatically: RNAi_primary
      WBRNAi00092211 Inferred_automatically: RNAi_primary
      WBRNAi00063059 Inferred_automatically: RNAi_primary
      WBRNAi00092212 Inferred_automatically: RNAi_primary
      WBRNAi00010797 Inferred_automatically: RNAi_primary
      WBRNAi00092210 Inferred_automatically: RNAi_primary
      WBRNAi00066418 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9013
      Expr14870
      Expr14871
      Expr14872
      Expr14873
      Expr1027360
      Expr1031807
      Expr1144676
      Expr2014534
      Expr2032773
    Drives_construct: WBCnstr00035845
      WBCnstr00041566
    Construct_product: WBCnstr00035845
      WBCnstr00041566
    Antibody: WBAntibody00002133
    Microarray_results (20)
    Expression_cluster: WBPaper00037624:ets-4(ok165)_downregulated
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00038061:aldicarb_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046421:cdc-48.2(tm659)_upregulated
      WBPaper00048910:Apoptosis-induced_mRNA-interacting_protein
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_nucleus_expressed
      WBPaper00051404:alg-5(ram2)_downregulated
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059490:dcr-1(m9375)_downregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:RIH
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:tub-2_4713-daf-2_5288
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062143:PQN-59_interacting
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_upregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00066110:Doxorubicin_downregulated_diploid
      cgc4489_group_5
      cgc4489_group_16
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00027758:Group_IV
      WBPaper00029437:dcr-1_upregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_F
      WBPaper00037147:heatshock_upregulated
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
    Interaction (97)
  Map_info: Map: V Position: 6.28588 Error: 0.001447
    Positive: Positive_clone: C15H11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4552
        4553
    Pseudo_map_position
  Reference (20)
  Remark: Sequence connection from [source BK Felber]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    Please note that this publication erroneously cited nfx-1. The correct gene is nxf-1 Paper_evidence: WBPaper00041879
  Method: Gene