WormBase Tree Display for Gene: WBGene00002254

WBGene00002254 SMap: S_parent: Sequence: F40F4
  Identity: Version: 1
    Name: CGC_name: lbp-2 Person_evidence: WBPerson492
      Sequence_name: F40F4.2
      Molecular_name: F40F4.2
        F40F4.2.1
        CE04532
        F40F4.2.2
      Other_name: CELE_F40F4.2 Accession_evidence: NDB BX284606
      Public_name: lbp-2
    DB_info: Database: AceView gene XD881
        WormQTL gene WBGene00002254
        WormFlux gene WBGene00002254
        NDB locus_tag CELE_F40F4.2
        Panther gene CAEEL|WormBase=WBGene00002254|UniProtKB=Q20224
          family PTHR22725
        NCBI gene 180617
        RefSeq protein NM_076157.10
        SwissProt UniProtAcc Q20224
        UniProt_GCRP UniProtAcc Q20224
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lbp
    Allele (11)
    RNASeq_FPKM (74)
    GO_annotation: 00067530
      00067531
      00067532
      00110319
    Ortholog (29)
    Paralog: WBGene00002253 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00002259 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002257 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002260 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00021486 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00002256 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00002255 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: lbp-2 encodes a homolog of the novel fatty acid binding protein, As-p18, found in the parasitic nematode Ascaris suum; As-p18 is a member of a family of small intracellular fatty acid binding proteins (iFABPs); the expression pattern of lpb-2 is consistent with it being secreted into the perienteric fluid where it may play a role in lipid transport beween the intestine and body wall; a lbp-2 promoter::gfp fusion reporter is restricted to body wall muscle cells abutting the pseudocoelom. Paper_evidence: WBPaper00003911
            WBPaper00012717
          Curator_confirmed: WBPerson324
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F40F4.2
    Corresponding_transcript (2)
    Other_sequence (22)
    Associated_feature: WBsf647927
      WBsf235463
      WBsf235464
  Experimental_info: RNAi_result: WBRNAi00070738 Inferred_automatically: RNAi_primary
      WBRNAi00070739 Inferred_automatically: RNAi_primary
      WBRNAi00088955 Inferred_automatically: RNAi_primary
      WBRNAi00102643 Inferred_automatically: RNAi_primary
      WBRNAi00001625 Inferred_automatically: RNAi_primary
      WBRNAi00046864 Inferred_automatically: RNAi_primary
      WBRNAi00014656 Inferred_automatically: RNAi_primary
      WBRNAi00032031 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1028663
      Expr1150731
      Expr2013019
      Expr2031251
    Drives_construct: WBCnstr00036357
    Construct_product: WBCnstr00036357
    Microarray_results (21)
    Expression_cluster: WBPaper00005700:secreted_protein
      WBPaper00026640:Development_Group_VI
      WBPaper00031040:Cluster_3
      WBPaper00032425:down_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00035269:cde-1_regulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037946:LIN-39_interacting
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_embryo_enriched
      WBPaper00037950:coelomocytes_embryo_SelectivelyEnriched
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038357:atx-3_regulated_heat-shock
      WBPaper00040755:LRRK2(G2019S)-Tau_vs_N2_upregulated
      WBPaper00040755:LRRK2(G2019S)-Tau_vs_Tau_upregulated
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044128:daf-2(e1370)_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_Day10
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00045316:prg-1_downregulated_L2
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046121:ecdoderm_unique
      WBPaper00046446:rapid-synthesized_YoungAdult
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050636:aging_regulated_insoluble_protein
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051352:Long-Term-Association-Memory_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053321:mes-4(RNAi)_downregulated_fed-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056900:PID-3_interacting
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-1(or286)_downregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059739:hira-1(gk835598)_downregulated_L4
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061045:Y56A3A.22(cck200)_upregulated
      WBPaper00061081:E.faecalis_downregulated_N2
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:BWM_anterior
      WBPaper00061340:BWM_far_posterior
      WBPaper00061340:hmc
      WBPaper00061340:Parent_of_AMsh_URB
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061527:nspc-1_614-nspc-10_22525
      WBPaper00061651:Coelomocyte_enriched
      WBPaper00061651:hmc_enriched
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_protein
      WBPaper00064005:starvation_upregulated_N2_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064716:paraquat_downregulated
      WBPaper00064789:Day9_vs_Day1_upregulated_neuron
      WBPaper00064789:Day12_vs_Day1_upregulated_neuron
      WBPaper00064841:tent-5(tm3504)_downregulated_transcript
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064952:Day5_vs_L4_upregulated_25C
      WBPaper00064952:Day10_vs_Day1_upregulated_25C
      WBPaper00064952:Day10_vs_L4_upregulated_25C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065623:59
      WBPaper00065623:103
      WBPaper00065841:7_0
      WBPaper00065841:7_1
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:38_0
      WBPaper00065841:38_1
      WBPaper00065841:38_2
      WBPaper00065841:38_3
      WBPaper00065841:102_0
      WBPaper00065841:110_0
      WBPaper00065841:110_1
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      cgc4386_cluster_1_3
      cgc4489_group_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026629:L4_hermaphrodite_enriched
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_D
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00037113:CPF_16C_down-regulated
      WBPaper00039835:ifg-1_upregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:TA100_up
      WBPaper00040963:TA300_up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction (263)
  Map_info: Map: X Position: -10.6457
    Positive: Positive_clone: F40F4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene