WormBase Tree Display for Gene: WBGene00001682

WBGene00001682 SMap: S_parent: Sequence: F08B6
  Identity: Version: 1
    Name: CGC_name: gpc-2 Person_evidence: WBPerson490
      Sequence_name: F08B6.2
      Molecular_name: F08B6.2
        F08B6.2.1
        CE20656
      Other_name: CELE_F08B6.2 Accession_evidence: NDB BX284601
      Public_name: gpc-2
    DB_info: Database (9)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gpc
    Allele: WBVar00336868
      WBVar00645701
      WBVar00645702
      WBVar00645703
      WBVar01499786
      WBVar01499054
      WBVar00296739
      WBVar01498959
    RNASeq_FPKM (74)
    GO_annotation: 00012456
      00012457
      00012458
      00109308
      00109309
      00109310
      00109311
      00109312
    Ortholog (14)
    Paralog: WBGene00001681
    Structured_description: Concise_description: gpc-2 encodes one of two C. elegans heterotrimeric G protein gamma subunits; gpc-2 is required, along with its partner GPB-1, a G protein beta subunit, for proper mitotic spindle positioning and orientation during early embryonic cell divisions; to date, GPC-2 expression has been reported in electrically excitable cells (all neurons and muscles). Paper_evidence: WBPaper00004576
            WBPaper00005150
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in muscle cell and neurons. Is an ortholog of human GNG13 (G protein subunit gamma 13). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F08B6.2
    Corresponding_transcript: F08B6.2.1
    Other_sequence (25)
    Associated_feature: WBsf643399
      WBsf976750
      WBsf983992
      WBsf1009988
      WBsf217884
  Experimental_info: RNAi_result (18)
    Expr_pattern: Expr1830
      Expr4698
      Expr1018561
      Expr1031002
      Expr1147948
      Expr2012202
      Expr2030438
    Drives_construct: WBCnstr00001703
      WBCnstr00012179
      WBCnstr00036774
    Construct_product: WBCnstr00013346
      WBCnstr00036774
    Microarray_results (22)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00038289:oocyte_protein
      WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00040209:B.thuringiensis_upregulated_N2
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040285:H2S_24hr_upregulated
      WBPaper00040560:hpl-2_embryo_upregulated
      WBPaper00044128:DietaryRestriction_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00046303:P.aeruginosa_downregulated_protein
      WBPaper00046795:starvation_upregulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00053289:DREAM-target
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056284:ints-4(RNAi)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061340:ADE
      WBPaper00061340:AIA
      WBPaper00061340:AIB
      WBPaper00061340:AIM
      WBPaper00061340:AIN
      WBPaper00061340:ALM_BDU
      WBPaper00061340:ALN
      WBPaper00061340:AUA
      WBPaper00061340:AVA
      WBPaper00061340:AVB
      WBPaper00061340:AVD
      WBPaper00061340:AVG
      WBPaper00061340:AVJ
      WBPaper00061340:AVK
      WBPaper00061340:AVL
      WBPaper00061340:CAN
      WBPaper00061340:DA
      WBPaper00061340:DA_DB
      WBPaper00061340:DB
      WBPaper00061340:DD
      WBPaper00061340:DVC
      WBPaper00061340:FLP
      WBPaper00061340:Neuroblast_AIZ_FLP
      WBPaper00061340:PLM
      WBPaper00061340:PVP
      WBPaper00061340:PVT
      WBPaper00061340:RIA
      WBPaper00061340:RIB
      WBPaper00061340:RID
      WBPaper00061340:RIH
      WBPaper00061340:RIM
      WBPaper00061340:RIV
      WBPaper00061340:RME
      WBPaper00061340:SIA
      WBPaper00061340:SIB
      WBPaper00061340:SMB
      WBPaper00061340:SMD
      WBPaper00061340:URX
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061527:mrpl-54-lbp-4
      WBPaper00061651:ADE_enriched
      WBPaper00061651:AIZ_enriched
      WBPaper00061651:AVG_enriched
      WBPaper00061651:CEP_enriched
      WBPaper00061651:DA9_enriched
      WBPaper00061651:DA_enriched
      WBPaper00061651:DB01_enriched
      WBPaper00061651:DB_enriched
      WBPaper00061651:HSN_enriched
      WBPaper00061651:I1_enriched
      WBPaper00061651:I4_enriched
      WBPaper00061651:M1_enriched
      WBPaper00061651:MC_enriched
      WBPaper00061651:NSM_enriched
      WBPaper00061651:PDE_enriched
      WBPaper00061651:PLM_enriched
      WBPaper00061651:PVM_enriched
      WBPaper00061651:PVR_enriched
      WBPaper00061651:PVW_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:RIH_enriched
      WBPaper00061651:URA_enriched
      WBPaper00061651:VA12_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061651:VB_enriched
      WBPaper00061651:VC_4_5_enriched
      WBPaper00061651:VC_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00065258:anchor-cell_enriched
      cgc4386_cluster_5_5
      cgc4489_group_5
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Embryo_A_Class
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030839:Larval_A_Class
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00030985:Enterococcus_faecalis_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00035905:FBF-1_Associated
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_28
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MDE
      [cgc5767]:expression_class_MD_pd(23_min)
      [cgc5767]:expression_class_ME
    Interaction (18)
  Map_info: Map: I Position: 1.31097 Error: 0.000909
    Positive: Positive_clone: F08B6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (20)
  Remark: sdm changed subseq from e to 2 by inference of pfam match. 12/99
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene