| WBGene00000906 | SMap | S_parent | Sequence | F23B2 |
|---|
| Identity | Version | 3 |
| | Name | CGC_name | daf-10 | Person_evidence | WBPerson521 |
| | | | | | WBPerson41163 |
| | | Sequence_name | F23B2.4 |
| | | Molecular_name | F23B2.4 |
| | | | F23B2.4.1 |
| | | | CE40504 |
| | | Other_name | osm-4 |
| | | | ift-122 | Person_evidence | WBPerson41163 |
| | | | CELE_F23B2.4 | Accession_evidence | NDB | BX284604 |
| | | Public_name | daf-10 |
| | DB_info | Database (12) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | | | 2 | 16 Jun 2006 16:39:11 | WBPerson2970 | Event | Acquires_merge | WBGene00009074 |
| | | | 3 | 05 May 2023 12:43:53 | WBPerson51134 | Name_change | CGC_name | daf-10 |
| | | | | | | | Other_name | ift-122 |
| | | Acquires_merge | WBGene00009074 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | daf |
| | Reference_allele | WBVar00143964 |
| | Allele (124) |
| | Legacy_information | e1387 : defective dauer formation (daf-8 daf-2 suppressible) abnormal chemotaxis abnormal osmotic avoidance males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells cephalic neurons; octopamine deficient. ES1. ME0. NA2 (m79 p821 pka osm-4). |
| | | See daf-10. |
| | | See also e1387, p821 |
| | | [C.elegansII] e1387 : defective dauer formation; abnormal chemotaxis abnormal osmotic avoidance; males impotent; abnormal sensory anatomy especially amphidial neurons and sheath cells, cephalic neurons; Dyf (FITC uptake defective); octopamine deficient. ES1. ME0. OA10: m79, p821 (pka osm-4), m534mut, mn321mut, etc. [Starich et al. 1995; DR; SP] |
| | Strain | WBStrain00030799 |
| | | WBStrain00036760 |
| | | WBStrain00004318 |
| | | WBStrain00004878 |
| | | WBStrain00006213 |
| | RNASeq_FPKM (74) |
| | GO_annotation (20) |
| | Ortholog (43) |
| | Structured_description | Concise_description | daf-10 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex A component IFT122; daf-10 activity is required for intraflagellar transport and thus for proper development of amphid and phasmid neurons, dauer development, chemotaxis, and normal lifespan; a DAF-10::GFP fusion protein undergoes both anterograde and retrograde intraflagellar transport in amphid or phasmid sensory neurons. | Paper_evidence | WBPaper00000503 |
| | | | | | WBPaper00001393 |
| | | | | | WBPaper00001482 |
| | | | | | WBPaper00002087 |
| | | | | | WBPaper00003835 |
| | | | | | WBPaper00004715 |
| | | | | | WBPaper00026822 |
| | | | | | WBPaper00027360 |
| | | | | Curator_confirmed | WBPerson48 |
| | | | | | WBPerson1843 |
| | | | | Date_last_updated | 23 Feb 2007 00:00:00 |
| | | Automated_description | Involved in several processes, including non-motile cilium assembly; positive regulation of dauer larval development; and receptor localization to non-motile cilium. Located in ciliary basal body. Human ortholog(s) of this gene implicated in cranioectodermal dysplasia 1. Is an ortholog of human IFT122 (intraflagellar transport 122). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Potential_model | DOID:0080803 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13556) |
| Molecular_info | Corresponding_CDS | F23B2.4 |
| | Corresponding_CDS_history | F23B2.4:wp164 |
| | | F23B2.4:wp166 |
| | Corresponding_transcript | F23B2.4.1 |
| | Other_sequence (13) |
| | Associated_feature | WBsf652038 |
| Experimental_info | RNAi_result | WBRNAi00098609 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00013805 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00098640 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00045391 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00098675 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00098722 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr1015512 |
| | | Expr1030569 |
| | | Expr1149314 |
| | | Expr2010760 |
| | | Expr2028997 |
| | Drives_construct | WBCnstr00037204 |
| | Construct_product | WBCnstr00008557 |
| | | WBCnstr00017221 |
| | | WBCnstr00017229 |
| | | WBCnstr00037204 |
| | Regulate_expr_cluster | WBPaper00041876:daf-10(m79)_downreglated |
| | | WBPaper00041876:daf-10(m79)_upreglated |
| | Microarray_results (20) |
| | Expression_cluster | WBPaper00037950:all-neurons_embryo_enriched |
| | | WBPaper00037950:all-neurons_embryo_SelectivelyEnriched |
| | | WBPaper00037950:BAG-neuron_embryo_enriched |
| | | WBPaper00037950:BAG-neuron_embryo_SelectivelyEnriched |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00044260:1-methylnicotinamide_downregulated |
| | | WBPaper00044578:reduced-humidity_downregulated_microarray |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045390:ubc-9(RNAi)_downregulated |
| | | WBPaper00045918:96h_infection_recovery_upregulated |
| | | WBPaper00046012:tdp-1(ok803)_upregulated |
| | | WBPaper00046024:sleep_upregulated_oscillating |
| | | WBPaper00046121:ecdoderm_unique |
| | | WBPaper00046805:csr-1(RNAi)_upregulated_Set1 |
| | | WBPaper00046805:csr-1(RNAi)_upregulated_Set2 |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII |
| | | WBPaper00053771:up_at_dpy-7(e88) |
| | | WBPaper00054758:alg-1(gk204)_upregulated |
| | | WBPaper00055334:DLC-1_interacting |
| | | WBPaper00055354:Psora_upregulated |
| | | WBPaper00055565:AVK_enriched |
| | | WBPaper00055971:nhl-2(ok818)_25C_downregulated |
| | | WBPaper00056161:male_enriched_siRNA |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_embryo |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00057041:spc-1(cas971)_downregulated |
| | | WBPaper00057041:unc-70(cas983)_downregulated |
| | | WBPaper00057068:ints-4(RNAi)_upregulated |
| | | WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061007:HB101_upregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:ADE |
| | | WBPaper00061340:ADF |
| | | WBPaper00061340:ADF_AWB |
| | | WBPaper00061340:ADL |
| | | WBPaper00061340:ADL_parent |
| | | WBPaper00061340:ASE |
| | | WBPaper00061340:ASE_parent |
| | | WBPaper00061340:ASG |
| | | WBPaper00061340:ASG_AWA |
| | | WBPaper00061340:ASH |
| | | WBPaper00061340:ASI_parent |
| | | WBPaper00061340:ASJ |
| | | WBPaper00061340:ASK |
| | | WBPaper00061340:ASK_parent |
| | | WBPaper00061340:AWA |
| | | WBPaper00061340:AWB |
| | | WBPaper00061340:AWC |
| | | WBPaper00061340:BAG |
| | | WBPaper00061340:CEP |
| | | WBPaper00061340:IL1 |
| | | WBPaper00061340:IL1_parent |
| | | WBPaper00061340:IL2 |
| | | WBPaper00061340:Neuroblast_ADE_ADA |
| | | WBPaper00061340:Neuroblast_ASG_AWA |
| | | WBPaper00061340:Neuroblast_ASJ_AUA |
| | | WBPaper00061340:Neuroblast_HSN_PHB |
| | | WBPaper00061340:Neuroblast_URX_CEPDx |
| | | WBPaper00061340:OLL |
| | | WBPaper00061340:OLL_parent |
| | | WBPaper00061340:OLQ |
| | | WBPaper00061340:OLQ_parent |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061405:S.aureus_downregulated_starvation |
| | | WBPaper00061527:ckr-1-T09B9.3 |
| | | WBPaper00061753:csr-1(tor159)_upregulated_25C |
| | | WBPaper00061853:osm-3(dh441)_downregulated |
| | | WBPaper00061995:mter-4(syb3662syb3403)_downregulated |
| | | WBPaper00062103:neuron_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062497:xpf-1(tm2842)_upregulated |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064315:mes-3(bn199)_upregulated_EGCs |
| | | WBPaper00064315:mes-4(bn73)_upregulated_EGCs |
| | | WBPaper00064933:bcf-1(ylf1)_downregulated_transcript |
| | | WBPaper00064939:vit-5(RNAi)_upregulated |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065158:AFD_enriched |
| | | WBPaper00065581:hpk-1(pk1393)_upregulated |
| | | WBPaper00065841:25_0 |
| | | WBPaper00065841:25_1 |
| | | WBPaper00065841:47_0 |
| | | WBPaper00065841:71_0 |
| | | WBPaper00065841:74_0 |
| | | WBPaper00065841:77_0 |
| | | WBPaper00065841:81_0 |
| | | WBPaper00065841:84_0 |
| | | WBPaper00065841:99_0 |
| | | WBPaper00065841:100_0 |
| | | WBPaper00065841:129_0 |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | cgc4489_group_22 |
| | | WBPaper00006465:II_ethanol_late_induction |
| | | WBPaper00024671:AFD_AWB_vs_unsorted_upregulated |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00030839:Larval_Pan_Neuronal |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00039866:ClassComp_daf-19_downregulated |
| | | WBPaper00039866:SAM_daf-19_downregulated |
| | | WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2 |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00045960:L1-L4-lethargus_upregulated |
| | | WBPaper00045960:L4-lethargus_upregulated |
| | | WBPaper00046853:AOBr_LakeStobenseeAug_upregulated |
| | | WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo |
| | | [cgc6390]:intrinsic |
| | Interaction (32) |
| Map_info | Map | IV | Position | 4.05374 | Error | 0.000504 |
| | Well_ordered |
| | Positive | Positive_clone | EH#5 |
| | | | F23B2 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data (2) |
| Reference (86) |
| Method | Gene |
