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WormBase Tree Display for Gene: WBGene00000465

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Name Class

WBGene00000465SMapS_parentSequenceC07G2
IdentityVersion3
NameCGC_namecpg-1Paper_evidenceWBPaper00027679
Sequence_nameC07G2.1
Molecular_nameC07G2.1a
C07G2.1a.1
CE00665
C07G2.1b
CE33971
C07G2.1b.1
Other_namecej-1
CELE_C07G2.1Accession_evidenceNDBBX284603
Public_namecpg-1
DB_infoDatabaseAceViewgene3F579
WormQTLgeneWBGene00000465
WormFluxgeneWBGene00000465
NDBlocus_tagCELE_C07G2.1
PanthergeneCAEEL|WormBase=WBGene00000465|UniProtKB=Q17802
familyPTHR23301
NCBIgene175586
RefSeqproteinNM_001025989.5
NM_001025988.8
SwissProtUniProtAccQ17802
TREEFAMTREEFAM_IDTF316636
UniProt_GCRPUniProtAccQ17802
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
216 Jun 2006 15:10:10WBPerson2970Name_changeOther_namecpg-1
314 Jan 2008 11:23:07WBPerson2970Name_changeCGC_namecej-1 -> cpg-1
Other_namecej-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpg
Allele (40)
StrainWBStrain00032264
WBStrain00032265
WBStrain00005743
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (50)
ParalogWBGene00015102Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019833Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016534Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010351Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021005Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioncpg-1 encodes, by alternative splicing, two isoforms of a chondroitin proteoglycan; CPG-1 contains three chitin-binding peritrophin-A domains and two mucin-like regions; CPG-1 is individually dispensable for normal embryonic development; however, CPG-1 and CPG-2 are jointly required for osmotic integrity of early embryos, error-free chromosomal segregation during meiosis, polar body extrusion, association of the sperm pronucleus/centrosome complex (SPCC) with the early embryonic cortex, localization of PAR-2 in early embryos, posterior localization of P granules or PIE-1, and pseudocleavage; CPG-1, like CPG-2, is covalently linked to chondroitin, which itself is required for vulval morphogenesis, polar-body extrusion, and separation of the eggshell from the embryonic plasma membrane; cpg-1 mRNA, like that of cpg-2, is expressed specifically in the adult hermaphrodite germ line and is bound by GLD-1; CPG-1 has five potential chondroitin attachment sites, one of them verified by mass spectrometry, and transgenic CPG-1 synthesized in mammalian cells carries chondroitin sulfate chains; CPG-1's multiple peritrophin-A domains may enable mechanical cross-linking of chitin.Paper_evidence (9)
Curator_confirmedWBPerson567
Date_last_updated09 Apr 2007 00:00:00
Automated_descriptionEnables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure. Expressed in eggshell; germ line; and oocyte.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC07G2.1a
C07G2.1b
Corresponding_transcriptC07G2.1a.1
C07G2.1b.1
Other_sequence (49)
Associated_featureWBsf019203
WBsf645094
WBsf976109
WBsf976110
WBsf992144
WBsf992145
WBsf1014761
WBsf1014762
WBsf224744
Experimental_infoRNAi_resultWBRNAi00078684Inferred_automaticallyRNAi_primary
WBRNAi00040019Inferred_automaticallyRNAi_primary
WBRNAi00000152Inferred_automaticallyRNAi_primary
WBRNAi00022636Inferred_automaticallyRNAi_primary
WBRNAi00092482Inferred_automaticallyRNAi_primary
WBRNAi00007842Inferred_automaticallyRNAi_primary
WBRNAi00005076Inferred_automaticallyRNAi_primary
WBRNAi00028645Inferred_automaticallyRNAi_primary
WBRNAi00010402Inferred_automaticallyRNAi_primary
WBRNAi00092494Inferred_automaticallyRNAi_primary
Expr_patternExpr2109
Expr4104
Expr13068
Expr13388
Expr1023887
Expr1030269
Expr1144095
Expr2010482
Expr2028722
Drives_constructWBCnstr00015402
WBCnstr00037990
Construct_productWBCnstr00015402
WBCnstr00037990
Microarray_results (31)
Expression_clusterWBPaper00028451:Oogenic_protein
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032097:CGH-1-associated-mRNA
WBPaper00033065:isp-1-1(qm150)_upregulated
WBPaper00037047:aging_accelerated_insoluble_protein
WBPaper00037047:insoluble_protein
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:BAG-neuron_embryo_enriched
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:germline-precursors_embryo_enriched
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:pharyngeal-muscle_embryo_enriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00038168:lin-15B(n744)_upregulated
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00040446:insoluble_protein
WBPaper00041071:spe-44_upregulated
WBPaper00041954:ethanol_upregulated
WBPaper00044037:eat-2_downregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:rising_dev_expression
WBPaper00044760:germline_specific
WBPaper00044786:emr-1(gk119)_downregulated
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
WBPaper00045050:csr-1(hypomorph)_downregulated
WBPaper00045050:drh-3 (ne4253)_downregulated
WBPaper00045316:prg-1_downregulated_L4
WBPaper00045420:fertilization_downregulated_protein
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045486:starvation_upregulated
WBPaper00045521:Oogenic
WBPaper00045571:germline-ablation_downregulated
WBPaper00045618:fbf-1_downregulated
WBPaper00045618:puf-8_downregulated
WBPaper00045729:gld-2(RNAi)_downregulated
WBPaper00045774:clk-1_upregulated
WBPaper00046012:tdp-1(ok803)_downregulated
WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048579:aging_upregulated
WBPaper00048611:MnCl2_downregulated
WBPaper00048762:FOG-1_associated
WBPaper00048762:FOG-3_associated
WBPaper00048988:neuron_expressed
WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050522:mafr-1(tm6082)_downregulated
WBPaper00050686:glp-1(e2141)_downregulated
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051265:F1_morc-1(tm6048)_downregulated
WBPaper00051404:alg-2(ok304)_downregulated
WBPaper00051461:pig-1(gm344)_upregulated
WBPaper00051558:fog-2(q71)_regulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053154:human-amyloid-beta_tau_regulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053289:DREAM-target
WBPaper00053302:alovudine_24h_regulated
WBPaper00053302:zidovudine_24h_regulated
WBPaper00053321:PGCs_enriched_NuGen
WBPaper00053388:dauer_regulated_Cluster2
WBPaper00053599:female_vs_male_upregulated
WBPaper00053599:mitosis_vs_meiosis_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053657:N2_M.humicola-infection_24hr
WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
WBPaper00053814:25C_downregulated_PY79
WBPaper00054493:hpl-2(tm1489)_downregulated
WBPaper00054792:FOG-3_interacting
WBPaper00055013:hmg-3(bar24)_upregulated
WBPaper00055049:S.gordonii_downregulated
WBPaper00055103:thoc-5(wy822)_downregulated
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00055354:Rapamycin-Allantoin_upregulated
WBPaper00055354:Rapamycin_upregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055364:uaf-1(n4588)_upregulated
WBPaper00055648:germline_expressed
WBPaper00055804:FBF-1-FBF-2-associated_oogenic-enriched
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056169:rrf-3(pk1426)_upregulated_L4
WBPaper00056284:ints-5(RNAi)_downregulated
WBPaper00056290:hsp-6(mg585)_downregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056826:hmc_biased
WBPaper00056868:P.aeruginosa_upregulated_smallRNA
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057154:HeatShock_downregulated_mRNA
WBPaper00057288:Cold_downregulated_transcript
WBPaper00058598:mex-1(or286)_downregulated
WBPaper00058598:mex-3(eu149)_downregulated
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058691:sin-3(tm1276)_upregulated
WBPaper00058711:paraquat_upregulated
WBPaper00058886:anp-1(ok608)_downregulated
WBPaper00059174:MEG-3_interacting
WBPaper00059440:GLP-1_represseded
WBPaper00059440:LAG-1_repressed_48hr-auxin
WBPaper00059664:srbc-48(ac23)_downregulated
WBPaper00059728:5ug_cholesterol_downregulated
WBPaper00059728:20ug_cholesterol_downregulated
WBPaper00059739:hira-1(gk835598)_upregulated_L4
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060014:set-2(zr2012)_downregulated
WBPaper00060100:SiNP_upregulated_mRNA
WBPaper00060278:atp-2(RNAi)_upregulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060445:ikb-1(nr2027)_upregulated_L4
WBPaper00060445:nfki-1(cer1)_downregulated_L1
WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
WBPaper00060445:nfki-1(cer1)_upregulated_L4
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060661:sensory-neuron_depleted
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060871:M.humicola-infection_48h_regulated
WBPaper00060909:atfs-1(cmh15)_upregulated
WBPaper00060909:atfs-1(et18)_upregulated
WBPaper00060951:mrpl-2(osa3)_upregulated
WBPaper00061007:HB101_downregulated
WBPaper00061007:S.aquatilis_downregulated
WBPaper00061045:Y56A3A.22(cck200)_downregulated
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061340:g2_parent
WBPaper00061340:Germline
WBPaper00061341:28C_24h_downregulated
WBPaper00061527:puf-3-oma-2_18268
WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
WBPaper00061613:human-amyloid-beta_upregulated
WBPaper00061651:Germline_enriched
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062118:neural-HSF-1_upregulated
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062446:nhr-8(hd117)_downregulated
WBPaper00062456:doxycycline_downregulated_CB4856_protein
WBPaper00062456:doxycycline_downregulated_CB4856_transcript
WBPaper00062456:doxycycline_downregulated_N2_protein
WBPaper00062497:xpf-1(tm2842)_downregulated
WBPaper00062669:extracellular-vesicle_protein
WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
WBPaper00064403:Heat-killed-E.Coli_upregulated
WBPaper00064502:spe-44(fx110)_upregulated
WBPaper00064505:tamoxifen_upregulated
WBPaper00064532:pals-25(icb98)_upregulated
WBPaper00064716:paraquat_upregulated
WBPaper00064788:ketamine_upregulated
WBPaper00064871:hypoxia_upregulated_F1
WBPaper00064952:Day5_vs_L4_upregulated_20C
WBPaper00064952:Day5_vs_L4_upregulated_25C
WBPaper00064952:Day10_vs_L4_upregulated_20C
WBPaper00064952:Day10_vs_L4_upregulated_25C
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065096:25C_vs_20C_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065096:npr-8(ok1439)_upregulated_Day1_20C
WBPaper00065120:body-muscle-transcriptome
WBPaper00065158:AFD_depleted
WBPaper00065258:anchor-cell_depleted
WBPaper00065288:mdt-15(tm2182)_upregulated
WBPaper00065315:mating_upregulated_Day2-7
WBPaper00065623:18
WBPaper00065841:29_0
WBPaper00065926:pgph-2(overepxreesion)_upregulated
WBPaper00065984:pals-17(syb3980)_upregulated
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066085:hda-3(ok1991)_downregulated
WBPaper00066110:Doxorubicin_downregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_downregulated
WBPaper00066118:cyclobutrifluram_upregulated
cgc4386_cluster_3_1
cgc4489_group_2
WBPaper00025032:cluster_1
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00027758:Group_I
WBPaper00034739:N2lessDR1350
WBPaper00034757:down_by_oxidative_stress
WBPaper00035084:L2_enriched_AIN-2_IP
WBPaper00035873:dpy-10_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Atrazine_regulated
WBPaper00036123:Cadmium_regulated
WBPaper00036130:mir-243_down_regulated
WBPaper00036286:Pattern_F
WBPaper00036383:ash-2_L3_regulated
WBPaper00037113:CPF_16C_down-regulated
WBPaper00037695:LD_3-day
WBPaper00037901:GLD-1_mRNA_targets
WBPaper00038172:aak-2overexpression_up_regulated
WBPaper00038172:tax-6null_up_regulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040821:Au-NP_regulated
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00041002:HF_3d_2.0mM_Down
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00042331:a-SWCNTs_downregulated
WBPaper00042548:miRISC_enriched
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00049311:AgNO3_regulated
WBPaper00051387:Triclosan_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00056330:mrps-5(RNAi)_downregulated
[cgc5767]:cluster_1
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(23_min)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
[cgc6390]:Cluster_E
[cgc6390]:oogenesis-enriched
Interaction (213)
Map_infoMapIIIPosition-3.15507Error0.001827
PositivePositive_cloneC07G2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (19)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene