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WormBase Tree Display for Gene: WBGene00010351

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Name Class

WBGene00010351SMapS_parentSequenceH02I12
IdentityVersion2
NameCGC_namecbd-1Person_evidenceWBPerson1822
Sequence_nameH02I12.1
Molecular_nameH02I12.1
H02I12.1.1
CE37527
Other_nameCELE_H02I12.1Accession_evidenceNDBBX284604
Public_namecbd-1
DB_infoDatabaseAceViewgene4M141
WormQTLgeneWBGene00010351
WormFluxgeneWBGene00010351
NDBlocus_tagCELE_H02I12.1
PanthergeneCAEEL|WormBase=WBGene00010351|UniProtKB=O45599
familyPTHR23301
NCBIgene178061
RefSeqproteinNM_069744.8
SwissProtUniProtAccO45599
TREEFAMTREEFAM_IDTF316636
UniProt_GCRPUniProtAccO45599
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
220 Jun 2008 11:28:19WBPerson2970Name_changeCGC_namecbd-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcbd
Allele (70)
StrainWBStrain00001924
WBStrain00037208
RNASeq_FPKM (74)
GO_annotation00034833
00034834
00034835
00034836
00034837
00034838
00034839
00034840
00117784
00117785
Ortholog (46)
ParalogWBGene00000465Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00015102Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019833Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016534Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021005Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioncbd-1 encodes a large (1319-residue) protein with 12 chitin-binding peritrophin-A domains; cbd-1(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype due to defects in eggshell synthesis; CBD-1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin; the N-terminal region of CBD-1 forms a complex with PERM-2 and PERM-4 to promote structural integrity of the outer vitelline layer of the eggshell; other regions of CBD-1 interact with EGG-1/2 and CHS-1 to promote assembly of a functionally distinct complex involved in fertilization and the oocyte-to-embryo transition.Paper_evidenceWBPaper00025054
WBPaper00028588
WBPaper00029231
WBPaper00029232
WBPaper00055058
Person_evidenceWBPerson2357
Curator_confirmedWBPerson324
WBPerson567
Date_last_updated10 Oct 2018 00:00:00
Automated_descriptionPredicted to enable chitin binding activity. Involved in eggshell formation; positive regulation of protein localization to cell cortex; and positive regulation of protein localization to plasma membrane. Located in cell periphery. Expressed in germ line and oocyte.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSH02I12.1
Corresponding_CDS_historyH02I12.1:wp132
Corresponding_transcriptH02I12.1.1
Other_sequence (30)
Associated_feature (16)
Experimental_infoRNAi_resultWBRNAi00103413Inferred_automaticallyRNAi_primary
WBRNAi00007576Inferred_automaticallyRNAi_primary
WBRNAi00025783Inferred_automaticallyRNAi_primary
WBRNAi00085382Inferred_automaticallyRNAi_primary
WBRNAi00022672Inferred_automaticallyRNAi_primary
WBRNAi00049261Inferred_automaticallyRNAi_primary
WBRNAi00071467Inferred_automaticallyRNAi_primary
WBRNAi00008914Inferred_automaticallyRNAi_primary
Expr_patternChronogram245
Expr13857
Expr13860
Expr15012
Expr1022872
Expr1034519
Expr1153004
Expr2009738
Expr2027978
Drives_constructWBCnstr00002712
WBCnstr00019828
WBCnstr00031480
WBCnstr00040212
Construct_productWBCnstr00019828
WBCnstr00031480
WBCnstr00040212
Microarray_results (21)
Expression_cluster (287)
Interaction (306)
Map_infoMapIVPosition4.96662Error0.001078
PositivePositive_cloneH02I12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00011961
WBPaper00034850
WBPaper00036882
WBPaper00037715
WBPaper00052142
WBPaper00055058
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene