WormBase Tree Display for Gene: WBGene00015102
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| WBGene00015102 | SMap | S_parent | Sequence | B0280 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cpg-2 | |||||||
| Sequence_name | B0280.5 | ||||||||
| Molecular_name | B0280.5 | ||||||||
| B0280.5.1 | |||||||||
| CE31868 | |||||||||
| Other_name | CELE_B0280.5 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | cpg-2 | ||||||||
| DB_info | Database | AceView | gene | 3I192 | |||||
| WormQTL | gene | WBGene00015102 | |||||||
| WormFlux | gene | WBGene00015102 | |||||||
| NDB | locus_tag | CELE_B0280.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00015102|UniProtKB=P41996 | |||||||
| family | PTHR23301 | ||||||||
| NCBI | gene | 175991 | |||||||
| RefSeq | protein | NM_066150.14 | |||||||
| SwissProt | UniProtAcc | P41996 | |||||||
| TREEFAM | TREEFAM_ID | TF321561 | |||||||
| UniProt_GCRP | UniProtAcc | P41996 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 16 Jun 2006 15:10:10 | WBPerson2970 | Name_change | CGC_name | cpg-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cpg | ||||||||
| Allele (38) | |||||||||
| Strain | WBStrain00032748 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (32) | |||||||||
| Paralog | WBGene00000465 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00010351 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00019833 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00016534 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00021005 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | cpg-2 encodes a chondroitin proteoglycan with six chitin-binding peritrophin-A domains and three mucin-like regions; CPG-2 is individually dispensable for normal embryonic development; however, CPG-2 and CPG-1 are jointly required for osmotic integrity of early embryos, error-free chromosomal segregation during meiosis, polar body extrusion, association of the sperm pronucleus/centrosome complex (SPCC) with the early embryonic cortex, localization of PAR-2 in early embryos, posterior localization of P granules or PIE-1, and pseudocleavage; CPG-2, like CPG-1, is covalently linked to chondroitin, which itself is required for vulval morphogenesis, polar-body extrusion, and separation of the eggshell from the embryonic plasma membrane; cpg-2 mRNA, like that of cpg-1, is expressed specifically in the adult hermaphrodite germ line and is bound by GLD-1; CPG-2 has 34 potential chondroitin attachment sites, four of them verified by mass spectrometry, and transgenic CPG-2 synthesized in mammalian cells carries chondroitin sulfate chains; CPG-2's multiple peritrophin-A domains may enable mechanical cross-linking of chitin. | Paper_evidence | WBPaper00004886 | |||||
| WBPaper00005540 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00005867 | |||||||||
| WBPaper00015261 | |||||||||
| WBPaper00027679 | |||||||||
| WBPaper00028588 | |||||||||
| WBPaper00029231 | |||||||||
| WBPaper00029232 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 09 Apr 2007 00:00:00 | ||||||||
| Automated_description | Enables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure and perivitelline space. Expressed in eggshell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | B0280.5 | |||||||
| Corresponding_CDS_history | B0280.5:wp86 | ||||||||
| Corresponding_transcript | B0280.5.1 | ||||||||
| Other_sequence (74) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00078684 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00092493 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005399 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033241 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092482 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038850 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022695 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr13069 | ||||||||
| Expr1012581 | |||||||||
| Expr1036453 | |||||||||
| Expr1143045 | |||||||||
| Expr2010483 | |||||||||
| Expr2028723 | |||||||||
| Drives_construct | WBCnstr00015403 | ||||||||
| WBCnstr00029085 | |||||||||
| Construct_product | WBCnstr00015403 | ||||||||
| WBCnstr00029085 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (274) | |||||||||
| Interaction (267) | |||||||||
| Map_info | Map | III | Position | -0.792379 | Error | 0.0004 | |||
| Positive | Positive_clone | B0280 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (19) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
