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WormBase Tree Display for Gene: WBGene00000465

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Name Class

WBGene00000465SMapS_parentSequenceC07G2
IdentityVersion3
NameCGC_namecpg-1Paper_evidenceWBPaper00027679
Sequence_nameC07G2.1
Molecular_nameC07G2.1a
C07G2.1a.1
CE00665
C07G2.1b
CE33971
C07G2.1b.1
Other_namecej-1
CELE_C07G2.1Accession_evidenceNDBBX284603
Public_namecpg-1
DB_infoDatabaseAceViewgene3F579
WormQTLgeneWBGene00000465
WormFluxgeneWBGene00000465
NDBlocus_tagCELE_C07G2.1
PanthergeneCAEEL|WormBase=WBGene00000465|UniProtKB=Q17802
familyPTHR23301
NCBIgene175586
RefSeqproteinNM_001025989.5
NM_001025988.8
SwissProtUniProtAccQ17802
TREEFAMTREEFAM_IDTF316636
UniProt_GCRPUniProtAccQ17802
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
216 Jun 2006 15:10:10WBPerson2970Name_changeOther_namecpg-1
314 Jan 2008 11:23:07WBPerson2970Name_changeCGC_namecej-1 -> cpg-1
Other_namecej-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcpg
Allele (40)
StrainWBStrain00032264
WBStrain00032265
WBStrain00005743
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (50)
ParalogWBGene00015102Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019833Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016534Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010351Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021005Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptioncpg-1 encodes, by alternative splicing, two isoforms of a chondroitin proteoglycan; CPG-1 contains three chitin-binding peritrophin-A domains and two mucin-like regions; CPG-1 is individually dispensable for normal embryonic development; however, CPG-1 and CPG-2 are jointly required for osmotic integrity of early embryos, error-free chromosomal segregation during meiosis, polar body extrusion, association of the sperm pronucleus/centrosome complex (SPCC) with the early embryonic cortex, localization of PAR-2 in early embryos, posterior localization of P granules or PIE-1, and pseudocleavage; CPG-1, like CPG-2, is covalently linked to chondroitin, which itself is required for vulval morphogenesis, polar-body extrusion, and separation of the eggshell from the embryonic plasma membrane; cpg-1 mRNA, like that of cpg-2, is expressed specifically in the adult hermaphrodite germ line and is bound by GLD-1; CPG-1 has five potential chondroitin attachment sites, one of them verified by mass spectrometry, and transgenic CPG-1 synthesized in mammalian cells carries chondroitin sulfate chains; CPG-1's multiple peritrophin-A domains may enable mechanical cross-linking of chitin.Paper_evidenceWBPaper00004886
WBPaper00005540
WBPaper00005654
WBPaper00005867
WBPaper00015261
WBPaper00027679
WBPaper00028588
WBPaper00029231
WBPaper00029232
Curator_confirmedWBPerson567
Date_last_updated09 Apr 2007 00:00:00
Automated_descriptionEnables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure. Expressed in eggshell; germ line; and oocyte.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC07G2.1a
C07G2.1b
Corresponding_transcriptC07G2.1a.1
C07G2.1b.1
Other_sequence (49)
Associated_featureWBsf019203
WBsf645094
WBsf976109
WBsf976110
WBsf992144
WBsf992145
WBsf1014761
WBsf1014762
WBsf224744
Experimental_infoRNAi_resultWBRNAi00078684Inferred_automaticallyRNAi_primary
WBRNAi00040019Inferred_automaticallyRNAi_primary
WBRNAi00000152Inferred_automaticallyRNAi_primary
WBRNAi00022636Inferred_automaticallyRNAi_primary
WBRNAi00092482Inferred_automaticallyRNAi_primary
WBRNAi00007842Inferred_automaticallyRNAi_primary
WBRNAi00005076Inferred_automaticallyRNAi_primary
WBRNAi00028645Inferred_automaticallyRNAi_primary
WBRNAi00010402Inferred_automaticallyRNAi_primary
WBRNAi00092494Inferred_automaticallyRNAi_primary
Expr_patternExpr2109
Expr4104
Expr13068
Expr13388
Expr1023887
Expr1030269
Expr1144095
Expr2010482
Expr2028722
Drives_constructWBCnstr00015402
WBCnstr00037990
Construct_productWBCnstr00015402
WBCnstr00037990
Microarray_results (31)
Expression_cluster (269)
Interaction (213)
Map_infoMapIIIPosition-3.15507Error0.001827
PositivePositive_cloneC07G2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (19)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene