WormBase Tree Display for Gene: WBGene00000224

WBGene00000224 Evidence: Author_evidence (2)
    From_analysis
  SMap: S_parent: Sequence: F26D10
  Identity: Version: 2
    Name: CGC_name: atgp-1
      Sequence_name: F26D10.9
      Molecular_name: F26D10.9a
        F26D10.9a.1
        CE32183
        F26D10.9b
        CE41226
        F26D10.9b.1
      Other_name: atg-1
        tag-95 CGC_data_submission
        CELE_F26D10.9 Accession_evidence: NDB BX284604
      Public_name: atgp-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 28 Feb 2008 11:15:59 WBPerson2970 Name_change: CGC_name: atgp-1
                Other_name: atg-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: atgp
    Allele (151)
    Strain: WBStrain00035583
    RNASeq_FPKM (74)
    GO_annotation: 00102866
      00102867
      00107057
    Ortholog (61)
    Paralog: WBGene00000225 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00008220 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00011409 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: atgp-1 encodes a predicted amino acid transporter glycoprotein subunit; when co-expressed in Xenopus oocytes with the AAT-1 or AAT-3 catalytic subunit, ATGP-1 is not able to facilitate amino acid uptake, even though ATGP-1 is able to covalently associate with AAT-1 or AAT-3 in the Xenopus expression system; however, when co-expressed with AAT-9, ATGP-1 is able to enhance the activity of this catalytic subunit; when expressed alone or with AAT-3, ATGP-1 localizes to the cell surface; when co-expressed with AAT-1, ATGP-1 localizes intracellularly. Paper_evidence: WBPaper00006408
            WBPaper00024381
          Curator_confirmed: WBPerson1843
          Date_last_updated: 03 Mar 2006 00:00:00
      Automated_description: Predicted to enable hydrolase activity, acting on glycosyl bonds. Predicted to be involved in carbohydrate metabolic process. Located in plasma membrane. Human ortholog(s) of this gene implicated in cystinuria. Is an ortholog of human SLC3A1 (solute carrier family 3 member 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9266 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11025)
  Molecular_info: Corresponding_CDS: F26D10.9a
      F26D10.9b
    Corresponding_CDS_history: F26D10.9:wp88
    Corresponding_transcript: F26D10.9a.1
      F26D10.9b.1
    Other_sequence (93)
    Associated_feature: WBsf646605
      WBsf660980
      WBsf660981
      WBsf717214
      WBsf981871
      WBsf229622
  Experimental_info: RNAi_result: WBRNAi00031434 Inferred_automatically: RNAi_primary
      WBRNAi00013927 Inferred_automatically: RNAi_primary
      WBRNAi00045611 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027197
      Expr1030141
      Expr1149524
      Expr2009498
      Expr2027735
    Drives_construct: WBCnstr00037993
    Construct_product: WBCnstr00037993
    Antibody: WBAntibody00000719
    Microarray_results (21)
    Expression_cluster: WBPaper00030922:glycosylated_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050094:mes-2(bn11)_upregulated
      WBPaper00050094:mes-6(bn66)_upregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053615:SMO-1_target
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00054192:cold-shock_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056855:his-72(uge40)_upregulated
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058942:henn-1(pk2295)_upregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059440:GLP-1_represseded
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061106:endu-2(tm4977)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AIZ
      WBPaper00061340:ALA
      WBPaper00061340:AVA
      WBPaper00061340:DA
      WBPaper00061340:g1A
      WBPaper00061340:g1P
      WBPaper00061340:OLQ_parent
      WBPaper00061340:pm8
      WBPaper00061340:SIB
      WBPaper00061340:Y
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hda-1(ne4748)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:R07G3.8_9125-ric-4_17408
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062497:xpf-1(tm2842)_downregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064201:SNA-3_interacting
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00065032:PAO1_vs_Delt.Pf4-infection_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_20
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00029437:rde-4_upregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_G
      WBPaper00037695:LD_3-day
      WBPaper00038304:octr-1_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040963:Q50_down
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048563:L1_DD_enriched
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053827:pyoverdine_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (33)
  Map_info: Map: IV Position: 16.2882 Error: 0.004481
    Positive: Positive_clone: F26D10 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4164
    Pseudo_map_position
  Reference: WBPaper00006408
    WBPaper00038491
    WBPaper00039044
    WBPaper00039099
    WBPaper00039519
    WBPaper00055090
    WBPaper00061547
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene