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WormBase Tree Display for Gene: WBGene00001483

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Name Class

WBGene00001483SMapS_parentSequenceC03C11
IdentityVersion1
NameCGC_namefog-3Person_evidenceWBPerson261
Sequence_nameC03C11.2
Molecular_nameC03C11.2
C03C11.2.1
CE07874
Other_nameCELE_C03C11.2Accession_evidenceNDBBX284601
Public_namefog-3
DB_infoDatabaseAceViewgene1K593
WormQTLgeneWBGene00001483
WormFluxgeneWBGene00001483
NDBlocus_tagCELE_C03C11.2
PanthergeneCAEEL|WormBase=WBGene00001483|UniProtKB=G5EDX7
familyPTHR17537
NCBIgene172863
RefSeqproteinNM_060245.6
TrEMBLUniProtAccG5EDX7
UniProt_GCRPUniProtAccG5EDX7
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:24WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfog
Allele (37)
Legacy_information[C.elegansII] q469 : XX animals transformed into females, XO animals somatically male, make oocytes in germ line. q469/Df similar. No dominant phenotypes. ES3 (adult XX), ME0.OA>10: q441, q443, q470, q520fdi, q502uvp,oz137, oz147. [Ellis and Kimble 1995; RE]
StrainWBStrain00022550
WBStrain00022589
WBStrain00022656
WBStrain00022661
WBStrain00040667
WBStrain00004780
WBStrain00005668
WBStrain00005669
WBStrain00048384
RNASeq_FPKM (74)
GO_annotation (13)
Ortholog (34)
ParalogWBGene00020380Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionfog-3 encodes a protein that has similarity, in its N-terminus, to the vertebrate Tob, BTG1, and BTG2 proteins that function in growth control and/or differentiation; in C. elegans, FOG-3 activity is required in the germ line throughout development for initiation and maintenance of spermatogenesis; fog-3 mRNA is expressed at highest levels in the L3, L4, and young adult stages of development, when spermatogenesis occurs; fog-3 transcription appears to be under the control of TRA-1A, which interacts with predicted TRA-1A binding sites in the fog-3 promoter in vitro.Paper_evidenceWBPaper00003882
WBPaper00004256
Curator_confirmedWBPerson1843
Date_last_updated27 Oct 2005 00:00:00
Automated_descriptionPredicted to enable transcription corepressor activity. Involved in cell fate specification; developmental process involved in reproduction; and positive regulation of oocyte development. Located in cytoplasm and nuclear periphery. Expressed in germ line. Is an ortholog of human TOB1 (transducer of ERBB2, 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC03C11.2
Corresponding_transcriptC03C11.2.1
Other_sequenceAY589605.1
Associated_featureWBsf979085
WBsf984884
WBsf218378
WBsf218379
Experimental_infoRNAi_result (11)
Expr_pattern (8)
Drives_construct (15)
Construct_product (16)
Regulate_expr_clusterWBPaper00048762:FOG-3_associated
WBPaper00054792:FOG-3_interacting
Microarray_results (19)
Expression_clusterWBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00041071:spe-44_upregulated
WBPaper00042194:nhr-114(RNAi)_upregulated
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
WBPaper00044260:nicotinc-acid_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00044760:germline_specific
WBPaper00045257:bar-1(ga80)_downregulated
WBPaper00045390:ubc-9(RNAi)_upregulated
WBPaper00045521:Spermatogenic
WBPaper00045861:wdr-5(ok1417)_upregulated
WBPaper00046805:csr-1(RNAi)_upregulated_Set1
WBPaper00046805:csr-1(RNAi)_upregulated_Set2
WBPaper00048762:FOG-3_associated
WBPaper00049498:npr-1(ur89)_regulated_1
WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050080:rbr-2(tm3141)_downregulated
WBPaper00050094:mes-2(bn11)_upregulated
WBPaper00050231:male_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00051265:F4_hrde-1(tm1200)_upregulated
WBPaper00051265:F4_morc-1(tm6048)_upregulated
WBPaper00051338:jmjd-5(tm3735)_upregulated_G0
WBPaper00052885:hrde-1(tm1200)-emb-4(qm31)_regulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(icb38)_downregulated
WBPaper00053321:mes-4(RNAi)_downregulated_fed-L1_Truseq
WBPaper00053321:PGCs_enriched_NuGen
WBPaper00053599:female_vs_male_downregulated
WBPaper00053599:mitosis_vs_meiosis_upregulated
WBPaper00053810:clk-1(qm30)_downregulated
WBPaper00053888:drh-3(rrr2)_upregulated
WBPaper00054493:hpl-2(tm1489)_upregulated
WBPaper00055013:hmg-3(bar24)_downregulated
WBPaper00055226:ADR-2_target_adr-1(tm668)
WBPaper00055226:ADR-2_target_N2
WBPaper00055354:Rifampicin_downregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055648:germline_expressed
WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
WBPaper00055827:pfd-6(gk493446)_downregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056034:pals-25(jy9)_upregulated
WBPaper00056039:ptl-1(ok621)_downregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056167:Cry5B_downregulated
WBPaper00056290:hsp-6(mg585)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:flcn-1(ok975)_downregulated
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057196:raga-1(ok386)_downregulated)
WBPaper00057288:Cold_upregulated_transcript
WBPaper00057288:iff-1(RNAi)_upregulated_transcript
WBPaper00058598:mex-1(or286)_downregulated
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00058725:sftb-1(cer39)_downregulated
WBPaper00058948:npr-8(ok1439)_downregulated_OP50
WBPaper00058948:npr-8(ok1439)_downregulated_PA14
WBPaper00058948:PA14_upregulated
WBPaper00059117:B.subtilis_upregulated
WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
WBPaper00059421:daf-1(m40)_downregulated
WBPaper00059605:mut-16(pk710)_upregulated
WBPaper00059605:simr-1(cmp36)_upregulated
WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
WBPaper00059728:5ug_cholesterol_upregulated
WBPaper00059728:20ug_cholesterol_upregulated
WBPaper00059739:hira-1(gk835598)_downregulated_L4
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060526:plp-1(ok2155)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060886:spr-5(by101)_upregulated
WBPaper00060921:tdc-1(n3419)_downregulated
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061424:Diet_MYb120_upregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061478:pie-1(ne4433)_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061479:ubc-9(ne4833)_upregulated
WBPaper00061527:mlt-9_22518-F33D4.6_14044
WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
WBPaper00061653:alh-4(hj221)_downregulated
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062156:jmjd-5(zr1234)_upregulated
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
WBPaper00062672:let-418(n3536)_upregulated
WBPaper00062715:blmp-1(s71)_upregulated
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064156:lipl-4(overexpress)_upregulated
WBPaper00064315:mes-3(bn199)_downregulated_PGCs
WBPaper00064315:mes-4(bn73)_downregulated_PGCs
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00064509:static-magnetic-field_upregulated
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064632:daf-2(e1370)_upregulated_intestine
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064769:him-17(me24)_upregulated
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065005:sams-3(RNAi)_upregulated
WBPaper00065005:sams-4(RNAi)_upregulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:N2_N.ferruginous_regulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
WBPaper00065258:anchor-cell_depleted
WBPaper00065623:144
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066038:mip-1(how5)_upregulated
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066085:hda-3(ok1991)_upregulated
WBPaper00066110:Doxorubicin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066232:hsf-1(RNAi)_upregulated_WT
cgc4489_group_15
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00035873:dpy-10_regulated
WBPaper00035873:osm-8_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00036286:Pattern_B
WBPaper00038304:octr-1_regulated
WBPaper00040823:alg-1(gk214)_upregulated
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00045673:colistin_downregulated
WBPaper00048989:N2_rapamycin_upregulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:Cluster_D
[cgc6390]:intrinsic
Interaction (64)
Anatomy_functionWBbtf0506
Map_infoMapIPosition4.49216Error0.029361
Well_ordered
PositivePositive_cloneC03C11Person_evidenceWBPerson159
Author_evidenceChen P-J
Singal A
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point (22)
Pos_neg_data (23)
ReferenceWBPaper00001883
WBPaper00001898
WBPaper00001966
WBPaper00001982
WBPaper00002112
WBPaper00002631
WBPaper00002644
WBPaper00002662
WBPaper00003279
WBPaper00003371
WBPaper00003372
WBPaper00003882
WBPaper00003942
WBPaper00003989
WBPaper00004137
WBPaper00004256
WBPaper00004349
WBPaper00004535
WBPaper00004832
WBPaper00005055
WBPaper00005065
WBPaper00005379
WBPaper00005670
WBPaper00006081
WBPaper00006369
WBPaper00010802
WBPaper00010860
WBPaper00011406
WBPaper00012444
WBPaper00012445
WBPaper00012537
WBPaper00012567
WBPaper00012610
WBPaper00012641
WBPaper00012682
WBPaper00012732
WBPaper00014441
WBPaper00014844
WBPaper00015488
WBPaper00015490
WBPaper00017958
WBPaper00018416
WBPaper00018421
WBPaper00018715
WBPaper00018734
WBPaper00019647
WBPaper00021048
WBPaper00021673
WBPaper00021755
WBPaper00021936
WBPaper00022289
WBPaper00022404
WBPaper00022405
WBPaper00022882
WBPaper00022892
WBPaper00023046
WBPaper00023251
WBPaper00023272
WBPaper00023295
WBPaper00024229
WBPaper00024494
WBPaper00025000
WBPaper00026212
WBPaper00026241
WBPaper00026645
WBPaper00026678
WBPaper00027025
WBPaper00027248
WBPaper00027294
WBPaper00027955
WBPaper00027960
WBPaper00029084
WBPaper00029090
WBPaper00030414
WBPaper00030834
WBPaper00031318
WBPaper00032481
WBPaper00033926
WBPaper00034420
WBPaper00034949
WBPaper00036244
WBPaper00038450
WBPaper00038491
WBPaper00038810
WBPaper00038880
WBPaper00039600
WBPaper00040947
WBPaper00041299
WBPaper00043722
WBPaper00043731
WBPaper00043754
WBPaper00044280
WBPaper00045052
WBPaper00048762
WBPaper00054792
WBPaper00055090
WBPaper00055155
WBPaper00055804
WBPaper00060545
WBPaper00062496
WBPaper00063338
WBPaper00063407
WBPaper00064354
WBPaper00065228
WBPaper00065711
PictureWBPicture0000013095
MethodGene