WormBase Tree Display for Gene: WBGene00001239

WBGene00001239 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F56H11
  Identity: Version: 1
    Name: CGC_name: elo-1 Person_evidence: WBPerson79
      Sequence_name: F56H11.4
      Molecular_name: F56H11.4a
        F56H11.4a.1
        CE05979
        F56H11.4b
        CE47981
        F56H11.4b.1
      Other_name: pea-1
        ceelo1 Accession_evidence: EMBL AF244356
        CELE_F56H11.4 Accession_evidence: NDB BX284604
      Public_name: elo-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: elo
    Allele (41)
    Strain: WBStrain00003343
      WBStrain00035534
      WBStrain00004008
      WBStrain00053449
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (45)
    Paralog: WBGene00001240 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001241 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001242 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001247 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001245 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001244 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001243 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001246 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: elo-1 encodes a component of C-18 polyunsaturated fatty acid (PUFA) elongase that is required for normal elongation of n-6 and n-3 20-carbon PUFA in vivo; ELO-1 is a condensing enzyme that elongates n-6 and n-7 (and, with less efficiency, n-3) series C18 PUFAs. Paper_evidence: WBPaper00002597
            WBPaper00004162
            WBPaper00004553
            WBPaper00005233
            WBPaper00005728
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable fatty acid elongase activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F56H11.4a
      F56H11.4b
    Corresponding_transcript: F56H11.4a.1
      F56H11.4b.1
    Other_sequence (58)
    Associated_feature: WBsf646238
      WBsf997434
      WBsf1017974
      WBsf228840
      WBsf228841
      WBsf228842
  Experimental_info: RNAi_result (13)
    Expr_pattern: Chronogram219
      Expr6235
      Expr1019784
      Expr1030785
      Expr1152525
      Expr2011278
      Expr2029514
    Drives_construct: WBCnstr00003814
      WBCnstr00037020
    Construct_product: WBCnstr00037020
    Microarray_results (27)
    Expression_cluster: WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1678
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032528:L3_enriched
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049626:UNC-75_target
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_downregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_embryo_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056284:ints-5(RNAi)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00056900:PID-3_interacting
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061527:R10H10.3-T21H3.1
      WBPaper00061651:Rectal_gland_enriched
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_protein
      WBPaper00064005:starvation_upregulated_N2_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064107:lin-35(n745)_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065149:lin-52(n771)_downregulated
      WBPaper00065158:AFD_depleted
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      cgc4386_cluster_1_5
      cgc4489_group_1
      cgc4489_group_20
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00025032:cluster_55
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_G
      WBPaper00037695:WC_5-day
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00044091:Bpseudomallei_repressed_8h
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      [cgc5767]:cluster_29
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(41_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_C
    Interaction (98)
    WBProcess: WBbiopr:00000121
  Map_info: Map: IV Position: 4.29121 Error: 0.001669
    Positive: Positive_clone: F56H11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4280
    Pseudo_map_position
  Reference: WBPaper00004162
    WBPaper00005233
    WBPaper00005539
    WBPaper00005728
    WBPaper00006465
    WBPaper00012981
    WBPaper00019021
    WBPaper00024532
    WBPaper00026481
    WBPaper00027109
    WBPaper00029292
    WBPaper00033382
    WBPaper00038491
    WBPaper00042257
    WBPaper00044659
    WBPaper00044760
    WBPaper00055090
    WBPaper00059947
    WBPaper00060352
    WBPaper00061547
    WBPaper00062388
    WBPaper00064105
    WBPaper00064505
    WBPaper00064721
  Remark: Sequence connection from [Watts JL, Browse JA]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene