WormBase Tree Display for Gene: WBGene00000450
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WBGene00000450 | SMap | S_parent | Sequence | K03A11 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | ceh-28 | Person_evidence | WBPerson83 | |||||
Sequence_name | K03A11.3 | ||||||||
Molecular_name | K03A11.3 | ||||||||
K03A11.3.1 | |||||||||
CE42603 | |||||||||
Other_name | CELE_K03A11.3 | Accession_evidence | NDB | BX284606 | |||||
Public_name | ceh-28 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | ceh | ||||||||
Allele (27) | |||||||||
Strain | WBStrain00002444 | ||||||||
WBStrain00001573 | |||||||||
WBStrain00029949 | |||||||||
WBStrain00032224 | |||||||||
WBStrain00052007 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (24) | |||||||||
Ortholog (29) | |||||||||
Paralog | WBGene00000428 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00000430 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00000434 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00000445 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000447 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
WBGene00000449 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00000463 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00004011 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WBGene00000584 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | ceh-28 encodes a homeodomain protein of the NK-2 family; ceh-28 is expressed in a single pharyngeal neuron, M4; within M4, CEH-28 functions to positively regulate the expression of dbl-1, which encodes a TGF-beta, and hence, TGF-beta signaling to ensure proper morphology of the pharyngeal g1 gland cells that are located adjacent to M4. | Paper_evidence | WBPaper00045065 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson324 | |||||||||
Date_last_updated | 09 Apr 2014 00:00:00 | ||||||||
Automated_description | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and regulation of neuron differentiation. Part of chromatin. Expressed in several structures, including ABalaappa; ABalaappaa; ABalaappap; ABalapapa; and M4 neuron. Human ortholog(s) of this gene implicated in several diseases, including aortic valve disease 2; congenital heart disease (multiple); and heart conduction disease (multiple). Is an ortholog of human NKX2-5 (NK2 homeobox 5). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0050650 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:32940) | ||||
DOID:0080334 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:1882 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:1681 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:1657 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488,HGNC:32940) | ||||||
DOID:0050820 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:0070125 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:6419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:0110112 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:1682 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
DOID:9955 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2488) | ||||||
Molecular_info | Corresponding_CDS | K03A11.3 | |||||||
Corresponding_CDS_history | K03A11.3:wp101 | ||||||||
K03A11.3:wp162 | |||||||||
K03A11.3:wp190 | |||||||||
Corresponding_transcript | K03A11.3.1 | ||||||||
Other_sequence | WBC02282_1 | ||||||||
CK854933.1 | |||||||||
JI213807.1 | |||||||||
Associated_feature | WBsf648642 | ||||||||
WBsf663461 | |||||||||
WBsf978476 | |||||||||
Gene_product_binds | WBsf945412 | ||||||||
WBsf945413 | |||||||||
Transcription_factor | WBTranscriptionFactor000466 | ||||||||
Experimental_info | RNAi_result | WBRNAi00049786 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00016509 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (13) | |||||||||
Drives_construct | WBCnstr00000378 | ||||||||
WBCnstr00002413 | |||||||||
WBCnstr00004336 | |||||||||
WBCnstr00007524 | |||||||||
WBCnstr00007530 | |||||||||
WBCnstr00012750 | |||||||||
WBCnstr00037528 | |||||||||
WBCnstr00042411 | |||||||||
Construct_product | WBCnstr00016730 | ||||||||
WBCnstr00037528 | |||||||||
WBCnstr00042411 | |||||||||
WBCnstr00042628 | |||||||||
Microarray_results (19) | |||||||||
Expression_cluster | WBPaper00029359_1280 | ||||||||
WBPaper00029359_1310 | |||||||||
WBPaper00029359_1364 | |||||||||
WBPaper00029359_1444 | |||||||||
WBPaper00029359_1504 | |||||||||
WBPaper00029359_1578 | |||||||||
WBPaper00029359_1604 | |||||||||
WBPaper00031040:TGF-beta_adult_upregulated | |||||||||
WBPaper00032528:L3_depleted | |||||||||
WBPaper00037950:BAG-neuron_blastula-embryo_expressed | |||||||||
WBPaper00037950:bodywall-muscle_L2-larva_expressed | |||||||||
WBPaper00037950:germline-precursors_blastula-embryo_expressed | |||||||||
WBPaper00037950:intestine_L1-larva_expressed | |||||||||
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq | |||||||||
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq | |||||||||
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray | |||||||||
WBPaper00045390:ubc-9(RNAi)_downregulated | |||||||||
WBPaper00045420:fertilization_downregulated_transcript | |||||||||
WBPaper00058598:mex-1(or286)_upregulated | |||||||||
WBPaper00058598:mex-3(eu149)_upregulated | |||||||||
WBPaper00058598:spn-4(tm291)_upregulated | |||||||||
WBPaper00061340:ALM_PLM | |||||||||
WBPaper00061340:g1A_g1P | |||||||||
WBPaper00061340:pm1_pm2 | |||||||||
WBPaper00061527:sre-33-ZK1025.1_8337 | |||||||||
WBPaper00061651:M4_enriched | |||||||||
WBPaper00062103:neuron_enriched | |||||||||
WBPaper00065841:51_1 | |||||||||
WBPaper00065841:126_0 | |||||||||
WBPaper00026929:sir-2.1_overexpression_regulated | |||||||||
WBPaper00041939:control_vs_UVC-EtBr-exposed_3h | |||||||||
WBPaper00041939:control_vs_UVC-exposed_3h | |||||||||
WBPaper00045673:colistin_upregulated | |||||||||
WBPaper00046548:dafachronic-acid_downregulated | |||||||||
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated | |||||||||
Interaction (33) | |||||||||
Product_binds_matrix | WBPmat00005550 | ||||||||
Map_info | Map | X | Position | 10.2061 | Error | 0.074367 | |||
Positive | Positive_clone | K03A11 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4372 | |||||||
5332 | |||||||||
Pseudo_map_position | |||||||||
Reference (19) | |||||||||
Remark | Sequence From Thomas.Burglin@unibas.ch Wed Mar 7 09:49:40 2001 | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |