WormBase Tree Display for Gene: WBGene00000463
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| WBGene00000463 | SMap | S_parent | Sequence | C28A5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ceh-43 | Person_evidence | WBPerson83 | |||||
| Sequence_name | C28A5.4 | ||||||||
| Molecular_name | C28A5.4a | ||||||||
| C28A5.4a.1 | |||||||||
| CE05325 | |||||||||
| C28A5.4b | |||||||||
| CE00677 | |||||||||
| C28A5.4b.1 | |||||||||
| Other_name | dopy-2 | Paper_evidence | WBPaper00042519 | ||||||
| WBPaper00032147 | |||||||||
| Person_evidence | WBPerson260 | ||||||||
| CELE_C28A5.4 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | ceh-43 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 26 Jul 2013 13:49:22 | WBPerson2970 | Event | Acquires_merge | WBGene00077777 | ||||
| Name_change | Other_name | dopy-2 | |||||||
| Acquires_merge | WBGene00077777 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ceh | ||||||||
| Allele (49) | |||||||||
| Legacy_information | [T Burglin] ceh-43 is the Dll homeobox gene on cosmid (C28A5) | ||||||||
| Strain (20) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (59) | |||||||||
| Paralog | WBGene00000430 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WBGene00000434 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00000446 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000449 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00000450 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00013583 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00004011 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00006380 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ceh-43 encodes a homeobox protein of the Distal-less (Dll) class that is required for development of the anterior hypodermis during embryonic morphogenesis for cell adhesion; ceh-43 affects embryonic and larval viability; it is predominantly expressed in the head hypdodermis, neuronal support cells and CAN neurons. | Paper_evidence | WBPaper00004947 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in dopaminergic neuron differentiation and embryo development. Predicted to be located in nucleus. Expressed in several structures, including ABarpa; anterior hypodermis; neuronal sheath cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including amelogenesis imperfecta type 4; orofacial cleft 15; and split hand-foot malformation (multiple). Is an ortholog of human DLX1 (distal-less homeobox 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0090024 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2918) | ||||
| DOID:0080408 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2917) | ||||||
| DOID:0111565 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2916) | ||||||
| DOID:0090021 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2918) | ||||||
| DOID:0110053 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2916) | ||||||
| Molecular_info | Corresponding_CDS | C28A5.4a | |||||||
| C28A5.4b | |||||||||
| Corresponding_transcript | C28A5.4a.1 | ||||||||
| C28A5.4b.1 | |||||||||
| Other_sequence | JI170941.1 | ||||||||
| Dviv_isotig14983 | |||||||||
| Oden_isotig26553 | |||||||||
| Oden_isotig23815 | |||||||||
| Dviv_isotig14984 | |||||||||
| Associated_feature (20) | |||||||||
| Transcription_factor | WBTranscriptionFactor000360 | ||||||||
| Experimental_info | RNAi_result (54) | ||||||||
| Expr_pattern (16) | |||||||||
| Drives_construct | WBCnstr00001220 | ||||||||
| WBCnstr00010372 | |||||||||
| WBCnstr00012596 | |||||||||
| WBCnstr00015207 | |||||||||
| WBCnstr00015208 | |||||||||
| WBCnstr00015209 | |||||||||
| WBCnstr00017943 | |||||||||
| WBCnstr00037517 | |||||||||
| Construct_product | WBCnstr00017887 | ||||||||
| WBCnstr00017943 | |||||||||
| WBCnstr00037517 | |||||||||
| WBCnstr00038833 | |||||||||
| Antibody | WBAntibody00001522 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (240) | |||||||||
| Interaction (173) | |||||||||
| Map_info | Map | III | Position | -3.17283 | Error | 0.000149 | |||
| Positive | Positive_clone | C28A5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4211 | |||||||
| 5582 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (27) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
