WormBase Tree Display for Gene: WBGene00000450
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| WBGene00000450 | SMap | S_parent | Sequence | K03A11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ceh-28 | Person_evidence | WBPerson83 | |||||
| Sequence_name | K03A11.3 | ||||||||
| Molecular_name | K03A11.3 | ||||||||
| K03A11.3.1 | |||||||||
| CE42603 | |||||||||
| Other_name | CELE_K03A11.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | ceh-28 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ceh | ||||||||
| Allele (27) | |||||||||
| Strain | WBStrain00002444 | ||||||||
| WBStrain00001573 | |||||||||
| WBStrain00029949 | |||||||||
| WBStrain00032224 | |||||||||
| WBStrain00052007 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (29) | |||||||||
| Paralog | WBGene00000428 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00000430 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00000434 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000445 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000447 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000449 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000463 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00004011 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00000584 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ceh-28 encodes a homeodomain protein of the NK-2 family; ceh-28 is expressed in a single pharyngeal neuron, M4; within M4, CEH-28 functions to positively regulate the expression of dbl-1, which encodes a TGF-beta, and hence, TGF-beta signaling to ensure proper morphology of the pharyngeal g1 gland cells that are located adjacent to M4. | Paper_evidence | WBPaper00045065 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 09 Apr 2014 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and regulation of neuron differentiation. Part of chromatin. Expressed in several structures, including ABalaappa; ABalaappaa; ABalaappap; ABalapapa; and M4 neuron. Human ortholog(s) of this gene implicated in several diseases, including aortic valve disease 2; congenital heart disease (multiple); and heart conduction disease (multiple). Is an ortholog of human NKX2-5 (NK2 homeobox 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (11) | ||||||||
| Molecular_info | Corresponding_CDS | K03A11.3 | |||||||
| Corresponding_CDS_history | K03A11.3:wp101 | ||||||||
| K03A11.3:wp162 | |||||||||
| K03A11.3:wp190 | |||||||||
| Corresponding_transcript | K03A11.3.1 | ||||||||
| Other_sequence | WBC02282_1 | ||||||||
| CK854933.1 | |||||||||
| JI213807.1 | |||||||||
| Associated_feature | WBsf648642 | ||||||||
| WBsf663461 | |||||||||
| WBsf978476 | |||||||||
| Gene_product_binds | WBsf945412 | ||||||||
| WBsf945413 | |||||||||
| Transcription_factor | WBTranscriptionFactor000466 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00049786 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00016509 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (13) | |||||||||
| Drives_construct | WBCnstr00000378 | ||||||||
| WBCnstr00002413 | |||||||||
| WBCnstr00004336 | |||||||||
| WBCnstr00007524 | |||||||||
| WBCnstr00007530 | |||||||||
| WBCnstr00012750 | |||||||||
| WBCnstr00037528 | |||||||||
| WBCnstr00042411 | |||||||||
| Construct_product | WBCnstr00016730 | ||||||||
| WBCnstr00037528 | |||||||||
| WBCnstr00042411 | |||||||||
| WBCnstr00042628 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (35) | |||||||||
| Interaction (33) | |||||||||
| Product_binds_matrix | WBPmat00005550 | ||||||||
| Map_info | Map | X | Position | 10.2061 | Error | 0.074367 | |||
| Positive | Positive_clone | K03A11 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4372 | |||||||
| 5332 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (19) | |||||||||
| Remark | Sequence From Thomas.Burglin@unibas.ch Wed Mar 7 09:49:40 2001 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
