WormBase Tree Display for Gene: WBGene00021095

WBGene00021095 SMap: S_parent: Sequence: W08F4
  Identity: Version: 3
    Name: CGC_name: mlt-8 Person_evidence: WBPerson545
            WBPerson3379
      Sequence_name: W08F4.6
      Molecular_name: W08F4.6
        W08F4.6.1
        CE37162
      Other_name: phi-54 Person_evidence: WBPerson2582
        CELE_W08F4.6 Accession_evidence: NDB BX284602
      Public_name: mlt-8
    DB_info: Database: AceView gene 2A860
        WormQTL gene WBGene00021095
        WormFlux gene WBGene00021095
        NDB locus_tag CELE_W08F4.6
        Panther gene CAEEL|WormBase=WBGene00021095|UniProtKB=O02106
          family PTHR17357
        NCBI gene 173448
        RefSeq protein NM_061358.9
        TrEMBL UniProtAcc O02106
        UniProt_GCRP UniProtAcc O02106
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 17 Mar 2005 13:54:35 WBPerson2970 Name_change: Other_name: phi-54
        3 28 Jul 2005 14:19:28 WBPerson2970 Name_change: CGC_name: mlt-8
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mlt
    Allele (59)
    Strain: WBStrain00051389
    RNASeq_FPKM (74)
    GO_annotation: 00026572
      00026573
      00026574
      00026575
      00125554
      00125555
    Ortholog (29)
    Structured_description: Concise_description: mlt-8 encodes a novel protein; during development, mlt-8 activity is required for molting; a mlt-8::gfp reporter is expressed in hypodermal cells and in a single posterior neuron. Paper_evidence: WBPaper00026763
          Curator_confirmed: WBPerson1843
          Date_last_updated: 16 Mar 2007 00:00:00
      Automated_description: Predicted to enable lipid transporter activity. Predicted to be involved in ganglioside catabolic process and lipid transport. Predicted to be located in cytoplasmic side of plasma membrane. Expressed in cuticle and hypodermal cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W08F4.6
    Corresponding_CDS_history: W08F4.6:wp127
    Corresponding_transcript: W08F4.6.1
    Other_sequence (82)
    Associated_feature: WBsf665330
      WBsf986442
      WBsf1011412
      WBsf222613
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr3695
      Expr16218
      Expr1017159
      Expr1039204
      Expr1158535
      Expr2013610
      Expr2031843
    Drives_construct: WBCnstr00006888
      WBCnstr00011606
      WBCnstr00042827
    Construct_product: WBCnstr00042827
    Microarray_results: SMD_W08F4.6
      182327_at
      A_12_P108800
      Aff_W08F4.6
      GPL13394_WBGene00021095
      GPL13914_W08F4.6
      GPL14144_W08F4.6_483-542_0.929_4_B
      GPL14144_W08F4.6_619-678_0.937_1_A
      GPL14144_W08F4.6_710-769_0.931_2_C
      GPL19516_CGZ0038825
      GPL21109_W08F4.6
      GPL3518_CE14722
      GPL8304_CE_WBGene00021095_A
      GPL8673_W08F4_6P00095
      GPL8673_W08F4_6P00330
      GPL8673_W08F4_6P00686
      GPL9450_W08F4.6
      cea2.p.48763
    Expression_cluster: WBPaper00030922:glycosylated_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037682:sma-2_sma-4_upregulated
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_CoreEnriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00041954:ethanol_upregulated
      WBPaper00042034:NO_upregulated_hsf-1(sy441)
      WBPaper00042477:prp-8(RNAi)_downregulated_RNAseq
      WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
      WBPaper00043945:MeHg_upregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00046121:ecdoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_downregulated_protein
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049098:hrde-1(tm1200)-induced_23C
      WBPaper00049134:hpk-1(pk1393)_upregulated
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049594:osm-9(ok1677)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050109:rBmTX14_upregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050182:lmn-1(L535P)_upregulated
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051265:F1_hrde-1(tm1200)_downregulated
      WBPaper00051265:F4_hrde-1(tm1200)_downregulated
      WBPaper00051352:Long-Term-Association-Memory_upregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054410:set-9(rw5)_downregulated
      WBPaper00054410:set-26(tm2467)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Metformin_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056039:ptrn-1(tm5597)_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056169:rrf-3(pk1426)_upregulated_L1
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00057347:nhr-14(tm1473)_downreglated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058927:high-redox-state_upregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
      WBPaper00059735:glucose_upregulated_N2
      WBPaper00059739:hira-1(gk835598)_downregulated_L1
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060273:vrk-1(RNAi)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:HB115_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:ADEsh
      WBPaper00061340:B_F_K_Kp_U_Y
      WBPaper00061340:Excretory_duct_and_pore
      WBPaper00061340:G2_and_W_blasts
      WBPaper00061340:hyp4_hyp5_hyp6
      WBPaper00061340:hyp7_AB_lineage
      WBPaper00061340:hyp7_C_lineage
      WBPaper00061340:Hypodermis
      WBPaper00061340:ILso
      WBPaper00061340:P_cell
      WBPaper00061340:Rectal_cell
      WBPaper00061340:Tail_hypodermis
      WBPaper00061340:Y
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061405:S.aureus_downregulated_starvation
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:mlt-9_22518-F33D4.6_14044
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00062118:neural-HSF-1_downregulated
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062456:doxycycline_upregulated_N2_protein
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00062534:fat-P-80_downregulated_ech-6(RNAi)
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_8h_downregulated_mRNA
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065560:E.coli-HB101_downregulated_F3
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065841:82_0
      WBPaper00065841:82_1
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_transcript
      WBPaper00065945:global-rpoa-2(-)_downregulated_transcript
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066004:tdp-1(csb38)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4386_cluster_4_6
      cgc4489_group_14
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032948:FedUp
      WBPaper00032948:MoltOssilate
      WBPaper00034739:N2lessDR1350
      WBPaper00034739:RIL17lessRIL14
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_G
      WBPaper00037695:CC_3-day
      WBPaper00038304:octr-1_regulated
      WBPaper00040185:nhr-23(RNAi)_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041207:CE_dauer_down
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042258:DA1877_downregulated_YoungAdult
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045437:Toxic-Se_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045865:biofilm_downregulated_B
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:Cluster_B
    Interaction: WBInteraction000321389
      WBInteraction000343600
      WBInteraction000347875
      WBInteraction000405174
      WBInteraction000412639
      WBInteraction000433115
      WBInteraction000437714
      WBInteraction000519291
  Map_info: Map: II Position: -15.5947 Error: 0.000138
    Positive: Positive_clone: W08F4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026373
    WBPaper00040293
    WBPaper00061662
    WBPaper00062715
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene