WormBase Tree Display for Gene: WBGene00011561

WBGene00011561 SMap: S_parent: Sequence: T07C4
  Identity: Version: 2
    Name (5)
    DB_info: Database: AceView gene 3L429
        WormQTL gene WBGene00011561
        WormFlux gene WBGene00011561
        NDB locus_tag CELE_T07C4.5
        Panther gene CAEEL|WormBase=WBGene00011561|UniProtKB=Q22288
          family PTHR21700
        NCBI gene 176448
        RefSeq protein NM_066884.7
        SwissProt UniProtAcc Q22288
        TREEFAM TREEFAM_ID TF315773
        UniProt_GCRP UniProtAcc Q22288
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 Sep 2007 11:48:01 WBPerson2970 Name_change: CGC_name: ttr-15
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ttr
    Allele (16)
    RNASeq_FPKM (74)
    GO_annotation: 00074769
      00074770
      00118790
    Ortholog (30)
    Paralog (62)
    Structured_description: Automated_description: Predicted to be located in cell surface and extracellular region. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T07C4.5
    Corresponding_transcript: T07C4.5.1
    Other_sequence (53)
    Associated_feature: WBsf645559
      WBsf993977
      WBsf225711
      WBsf225712
  Experimental_info: RNAi_result: WBRNAi00006128 Inferred_automatically: RNAi_primary
      WBRNAi00018347 Inferred_automatically: RNAi_primary
      WBRNAi00035294 Inferred_automatically: RNAi_primary
      WBRNAi00052727 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027293
      Expr1035096
      Expr1156338
      Expr2017579
      Expr2035719
    Drives_construct: WBCnstr00030559
    Construct_product: WBCnstr00030559
    Microarray_results (19)
    Expression_cluster: WBPaper00005700:secreted_protein
      WBPaper00025192:hda-1(RNAi)_upregulated
      WBPaper00031040:Cluster_3
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032009:nhr-40(ok667)_downregulated
      WBPaper00032009:nhr-40(ok667)_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00038213:E.coli(LF82)_72h_upregulated
      WBPaper00038289:oocyte_protein
      WBPaper00038357:atx-3_regulated_heat-shock
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044746:aging_upregulated_Day5
      WBPaper00044746:aging_upregulated_Day10
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045257:bar-1(ga80)_upregulated
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046303:P.aeruginosa_downregulated_protein
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_upregulated_protein
      WBPaper00046887:WNT-target
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048910:Apoptosis-induced_mRNA-interacting_protein
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049290:rsks-1(sv31)_upregulated
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049732:blmp-1(tm548)_vs_N2_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_20C_upregulated
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_specific
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_upregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054191:H3.3(null)_embryo_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055364:uaf-1(n4588)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056169:rrf-3(pk1426)_downregulated_L2
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056169:rrf-3(pk1426)_upregulated_L3
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057154:HeatShock_upregulated_miRNA-target
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058927:high-redox-state_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059537:ngn-1(ok2200)_upregulated
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059816:crh-1(n3315)_downrgulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060434:pH4.33_vs_pH6.33_downrgulated
      WBPaper00060703:nas-38(ok3407)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AMsh
      WBPaper00061340:ILsh_OLLsh_OLQsh
      WBPaper00061340:Z1_Z4
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061651:AMso_enriched
      WBPaper00061651:CEPsh_enriched
      WBPaper00061651:Spermatheca_enriched
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00062002:Day4-adult_secretome
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062335:sir-2.1(ok434)_upregulated_L3
      WBPaper00062347:blmp-1(tm548)_upregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062518:atf-4_regulated
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00063930:BRD-1_interacting
      WBPaper00063976:micu-1(bon20)_downregulated
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064735:bet-1(RNAi)_vs_N2_upregulated
      WBPaper00064735:bet-1(uth41)_vs_N2_upregulated
      WBPaper00064789:Day3_vs_Day1_upregulated_neuron
      WBPaper00064789:Day6_vs_Day1_upregulated_neuron
      WBPaper00064789:Day9_vs_Day1_upregulated_neuron
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064952:Day10_vs_L4_upregulated_20C
      WBPaper00064952:Day10_vs_L4_upregulated_25C
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065158:AFD_depleted
      WBPaper00065199:Transgeneration-starvation_regulated_fed
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065623:84
      WBPaper00065841:11_1
      WBPaper00065841:43_0
      WBPaper00065841:141_0
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      cgc4386_cluster_1_5
      cgc4489_group_9
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00034739:N2moreDR1350
      WBPaper00036286:Pattern_D
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040963:TA300_up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00055899:nitroguanidine_regulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction: WBInteraction000112700
      WBInteraction000144672
      WBInteraction000147185
      WBInteraction000151364
      WBInteraction000151871
      WBInteraction000163831
      WBInteraction000167903
      WBInteraction000168661
      WBInteraction000177062
      WBInteraction000179404
      WBInteraction000181938
      WBInteraction000182158
      WBInteraction000186867
      WBInteraction000190441
      WBInteraction000192405
      WBInteraction000194762
      WBInteraction000195766
      WBInteraction000196674
      WBInteraction000197560
      WBInteraction000197666
      WBInteraction000199434
      WBInteraction000200464
      WBInteraction000202193
      WBInteraction000203120
      WBInteraction000203532
      WBInteraction000207581
      WBInteraction000210891
      WBInteraction000210940
      WBInteraction000212220
      WBInteraction000220753
      WBInteraction000221876
      WBInteraction000222857
      WBInteraction000225619
      WBInteraction000228526
      WBInteraction000229111
      WBInteraction000230999
      WBInteraction000231026
      WBInteraction000231336
      WBInteraction000232227
      WBInteraction000235889
      WBInteraction000236104
      WBInteraction000239117
      WBInteraction000242311
      WBInteraction000245491
      WBInteraction000245642
      WBInteraction000246335
      WBInteraction000248678
      WBInteraction000250551
      WBInteraction000252179
      WBInteraction000252826
      WBInteraction000252994
      WBInteraction000254642
      WBInteraction000255675
      WBInteraction000257825
      WBInteraction000259844
      WBInteraction000260838
      WBInteraction000260928
      WBInteraction000261045
      WBInteraction000261678
      WBInteraction000263786
      WBInteraction000270874
      WBInteraction000271852
      WBInteraction000272531
      WBInteraction000272565
      WBInteraction000273479
      WBInteraction000276360
      WBInteraction000276441
      WBInteraction000276628
      WBInteraction000280452
      WBInteraction000280609
      WBInteraction000283697
      WBInteraction000283891
      WBInteraction000285264
      WBInteraction000286611
      WBInteraction000287740
      WBInteraction000290658
      WBInteraction000291998
      WBInteraction000292539
      WBInteraction000294075
      WBInteraction000294591
      WBInteraction000295596
      WBInteraction000297356
      WBInteraction000299513
      WBInteraction000300250
      WBInteraction000300828
      WBInteraction000301673
      WBInteraction000305884
      WBInteraction000306465
      WBInteraction000308540
      WBInteraction000310794
      WBInteraction000314135
      WBInteraction000315205
      WBInteraction000315626
      WBInteraction000316182
      WBInteraction000316771
      WBInteraction000318584
      WBInteraction000321965
      WBInteraction000323793
      WBInteraction000323869
      WBInteraction000324837
      WBInteraction000327685
      WBInteraction000330738
      WBInteraction000335043
      WBInteraction000340105
      WBInteraction000342029
      WBInteraction000342873
      WBInteraction000344895
      WBInteraction000346776
      WBInteraction000347481
      WBInteraction000348028
      WBInteraction000349579
      WBInteraction000352541
      WBInteraction000353489
      WBInteraction000354342
      WBInteraction000354359
      WBInteraction000355711
      WBInteraction000357082
      WBInteraction000359986
      WBInteraction000364074
      WBInteraction000366083
      WBInteraction000366456
      WBInteraction000369842
      WBInteraction000372492
      WBInteraction000373214
      WBInteraction000374554
      WBInteraction000375360
      WBInteraction000376108
      WBInteraction000377883
      WBInteraction000378856
      WBInteraction000382126
      WBInteraction000382740
      WBInteraction000385008
      WBInteraction000385419
      WBInteraction000386018
      WBInteraction000390606
      WBInteraction000391817
      WBInteraction000392126
      WBInteraction000393546
      WBInteraction000395503
      WBInteraction000397239
      WBInteraction000397374
      WBInteraction000398840
      WBInteraction000400145
      WBInteraction000402607
      WBInteraction000402964
      WBInteraction000402982
      WBInteraction000402997
      WBInteraction000404941
      WBInteraction000408608
      WBInteraction000409066
      WBInteraction000410051
      WBInteraction000415166
      WBInteraction000417862
      WBInteraction000421511
      WBInteraction000423476
      WBInteraction000426787
      WBInteraction000428086
      WBInteraction000430650
      WBInteraction000431025
      WBInteraction000439164
      WBInteraction000442772
      WBInteraction000443925
      WBInteraction000445062
      WBInteraction000445076
      WBInteraction000448269
      WBInteraction000448755
      WBInteraction000450916
      WBInteraction000454751
      WBInteraction000457106
      WBInteraction000458239
      WBInteraction000462115
      WBInteraction000462609
      WBInteraction000549461
      WBInteraction000552043
      WBInteraction000553209
      WBInteraction000570788
      WBInteraction000571900
  Map_info: Map: III Position: 2.38152 Error: 0.009884
    Positive: Positive_clone: T07C4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00049828
    WBPaper00062002
    WBPaper00063976
    WBPaper00064789
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene