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WormBase Tree Display for Gene: WBGene00000209

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Name Class

WBGene00000209SMapS_parentSequenceK07A12
IdentityVersion1
NameCGC_nameasg-1Person_evidenceWBPerson284
Sequence_nameK07A12.3
Molecular_nameK07A12.3
K07A12.3.1
CE11868
Other_nameCELE_K07A12.3Accession_evidenceNDBBX284601
Public_nameasg-1
DB_infoDatabaseAceViewgene1J269
WormQTLgeneWBGene00000209
WormFluxgeneWBGene00000209
NDBlocus_tagCELE_K07A12.3
PanthergeneCAEEL|WormBase=WBGene00000209|UniProtKB=P90921
familyPTHR12386
NCBIgene172673
RefSeqproteinNM_059951.8
SwissProtUniProtAccP90921
TREEFAMTREEFAM_IDTF313978
UniProt_GCRPUniProtAccP90921
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classasg
Allele (16)
StrainWBStrain00037232
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (39)
ParalogWBGene00000210Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionasg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology.Paper_evidenceWBPaper00004402
WBPaper00006028
WBPaper00006395
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ATP5MG (ATP synthase membrane subunit g).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:14247)
Molecular_infoCorresponding_CDSK07A12.3
Corresponding_transcriptK07A12.3.1
Other_sequence (100)
Associated_featureWBsf643541
WBsf643542
WBsf218193
Experimental_infoRNAi_result (21)
Expr_patternExpr1013546
Expr1030128
Expr1153799
Expr2009449
Expr2027686
Drives_constructWBCnstr00037663
Construct_productWBCnstr00037663
Microarray_results (19)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032528:L3_enriched
WBPaper00035073:mitochondria_protein
WBPaper00037086:biotin_regulated
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038118:aak-2(gt33)_downregulated
WBPaper00038289:oocyte_protein
WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
WBPaper00040965:lipid-droplet_associated_protein
WBPaper00044128:daf-2(e1370)_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00045774:clk-1_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048810:CoQ-deficiency_downregulated
WBPaper00048910:mRNA-interacting_protein
WBPaper00048988:neuron_expressed
WBPaper00049498:npr-1(ur89)_regulated_6
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050412:cco-1(RNAi)_downregulated_N2
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053388:dauer_regulated_Cluster6
WBPaper00053615:SMO-1_target
WBPaper00053814:25C_downregulated_OP50
WBPaper00055049:S.gordonii_downregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055482:pmt-2(RNAi)_downregulated
WBPaper00055648:germline_expressed
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056501:P.aeruginosa_downregulated_mitochondria-protein
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058948:PA14_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_protein
WBPaper00059471:EGL-43_interacting
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061341:28C_24h_downregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061527:F45H10.2-R53.4_21676
WBPaper00061651:ADF_enriched
WBPaper00061651:Germline_enriched
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062498:PPM-1.D_interacting
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00063976:micu-1(bon20)_downregulated
WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
WBPaper00064055:trl-1(cas1077)_downregulated_starved
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064122:vulva_transcriptome
WBPaper00064201:SNA-3_interacting
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_upregulated_WT
cgc4489_group_1
WBPaper00005475:Aging-regulated
WBPaper00025032:cluster_21
WBPaper00025032:cluster_29
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Enriched_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026980:intestine_enriched
WBPaper00030839:Embryo_A_Class
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030985:Erwinia_carotovora_downregulated
WBPaper00030985:Serratia_marcesens_downregulated
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032062:age_regulated_genes
WBPaper00036286:Pattern_B
WBPaper00036375:depleted_in_PVD_OLL
WBPaper00037113:Diazinon_16C_regulated
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
WBPaper00040858:eQTL_regulated_developing
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045960:L1-L4-lethargus_downregulated
WBPaper00045960:L4-lethargus_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:cluster_22
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
InteractionWBInteraction000107410
WBInteraction000107413
WBInteraction000107416
WBInteraction000107417
WBInteraction000124015
WBInteraction000127712
WBInteraction000127719
WBInteraction000127724
WBInteraction000131519
WBInteraction000132619
WBInteraction000133464
WBInteraction000135937
WBInteraction000148479
WBInteraction000153401
WBInteraction000153402
WBInteraction000153403
WBInteraction000153404
WBInteraction000153405
WBInteraction000153406
WBInteraction000153407
WBInteraction000153408
WBInteraction000153409
WBInteraction000153410
WBInteraction000153411
WBInteraction000153412
WBInteraction000153413
WBInteraction000153414
WBInteraction000153415
WBInteraction000153416
WBInteraction000153417
WBInteraction000153418
WBInteraction000153419
WBInteraction000153420
WBInteraction000153421
WBInteraction000153422
WBInteraction000153520
WBInteraction000153596
WBInteraction000154073
WBInteraction000154206
WBInteraction000155166
WBInteraction000155213
WBInteraction000155285
WBInteraction000155431
WBInteraction000155555
WBInteraction000155580
WBInteraction000155895
WBInteraction000155930
WBInteraction000156014
WBInteraction000156140
WBInteraction000156333
WBInteraction000164651
WBInteraction000171204
WBInteraction000171718
WBInteraction000174653
WBInteraction000182983
WBInteraction000187111
WBInteraction000190351
WBInteraction000197998
WBInteraction000198732
WBInteraction000199377
WBInteraction000200109
WBInteraction000200777
WBInteraction000201807
WBInteraction000210980
WBInteraction000215299
WBInteraction000226614
WBInteraction000232103
WBInteraction000236970
WBInteraction000237365
WBInteraction000239234
WBInteraction000245259
WBInteraction000247520
WBInteraction000260196
WBInteraction000260559
WBInteraction000265403
WBInteraction000273912
WBInteraction000278202
WBInteraction000284548
WBInteraction000287534
WBInteraction000297582
WBInteraction000310032
WBInteraction000311737
WBInteraction000312471
WBInteraction000315694
WBInteraction000320384
WBInteraction000321051
WBInteraction000323804
WBInteraction000324790
WBInteraction000326037
WBInteraction000331525
WBInteraction000332593
WBInteraction000336239
WBInteraction000342226
WBInteraction000345883
WBInteraction000347635
WBInteraction000351938
WBInteraction000370819
WBInteraction000389861
WBInteraction000390225
WBInteraction000391912
WBInteraction000397588
WBInteraction000405009
WBInteraction000407768
WBInteraction000409858
WBInteraction000424648
WBInteraction000424769
WBInteraction000429041
WBInteraction000442868
WBInteraction000443077
WBInteraction000448067
WBInteraction000450780
WBInteraction000451885
WBInteraction000462322
WBInteraction000536364
WBInteraction000536377
WBInteraction000536391
WBInteraction000537154
WBInteraction000539713
WBInteraction000551850
WBInteraction000552816
WBInteraction000554201
WBInteraction000559366
WBInteraction000569427
WBInteraction000570643
WBInteraction000573356
WBInteraction000579543
WBProcessWBbiopr:00000012
Map_infoMapIPosition3.01799Error0.000118
PositivePositive_cloneK07A12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkSequence connection from [Iino Y]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene