hc15ts : hermaphrodites and males grown at 25x produce spermatids that fail to activate into spermatozoa. Self-fertility < 1% (25x) 100% (16x). ES2 (adult). Similar phenotype in hc15/Df. NA3 (hc89 b26).
[C.elegansII] hc15ts : hermaphrodites and males grown at 25C produce spermatids that fail to activate into spermatozoa. Self-fertility < 1% (25C) 100% (16C). ES2 (adult). Similar phenotype in hc15/Df. OA2: hc89, b26. See also age-1. [Roberts and Ward 1982; BA; TJ; SL]
rrf-3 encodes an RNA-directed RNA polymerase (RdRP) homolog that inhibits somatic RNAi, and thus promotes activity of repeated genes (e.g., multicopy transgenic arrays); the effect of RRF-3 on RNAi is opposite to that of RRF-1 (which stimulates somatic RNAi), which might arise from competition by RRF-3 with RRF-1 or EGO-1 in RNAi formation; rrf-3 mutants are hypersensitive to somatic RNAi, and conversely suppress the activity of an integrated rol6 (su1006) transgene.
Predicted to enable RNA-dependent RNA polymerase activity. Involved in regulatory ncRNA-mediated heterochromatin formation and spermatogenesis. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Expressed in head and tail.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.