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WormBase Tree Display for Gene: WBGene00004918

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Name Class

WBGene00004918EvidencePaper_evidenceWBPaper00005457
SMapS_parentSequenceZK652
IdentityVersion1
NameCGC_namesnr-5Person_evidenceWBPerson167
Sequence_nameZK652.1
Molecular_nameZK652.1
ZK652.1.1
CE00446
Other_nameCELE_ZK652.1Accession_evidenceNDBBX284603
Public_namesnr-5
DB_infoDatabaseAceViewgene3I953
WormQTLgeneWBGene00004918
WormFluxgeneWBGene00004918
NDBlocus_tagCELE_ZK652.1
PanthergeneCAEEL|WormBase=WBGene00004918|UniProtKB=P34659
familyPTHR11021
NCBIgene176103
RefSeqproteinNM_066307.7
SwissProtUniProtAccP34659
TREEFAMTREEFAM_IDTF314481
UniProt_GCRPUniProtAccP34659
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsnr
AlleleWBVar01500260
WBVar01499774
StrainWBStrain00051877
RNASeq_FPKM (74)
GO_annotation00043796
00043797
00043798
00043799
00043800
00043801
00043802
00043803
00043804
00043805
00043806
00043807
00043808
00043809
00043810
00043811
00043812
00043813
00043814
00043815
00113328
Ortholog (36)
ParalogWBGene00003080Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionsnr-5 encodes an ortholog of human small nuclear ribonucleoprotein SmF, a protein that forms part of a heptameric complex required for biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human SmE and SmG orthologs (snr-6 and snr-7, respectively), snr-5 affects embryonic viability and nuclear association and localization of P granules in embryos, based on an RNAi assay; affects embryonic and larval viability based on large-scale RNAi assays; snr-5 is expressed in embryos and adult gonads.Paper_evidenceWBPaper00005654
Curator_confirmedWBPerson48
Date_last_updated11 Jul 2005 00:00:00
Automated_descriptionPredicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol and nucleus. Predicted to be part of U1 snRNP; catalytic step 2 spliceosome; and pICln-Sm protein complex. Expressed in several structures, including enteric muscle; excretory cell; hypodermis; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Is an ortholog of human SNRPF (small nuclear ribonucleoprotein polypeptide F).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9261Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11162)
Molecular_infoCorresponding_CDSZK652.1
Corresponding_transcriptZK652.1.1
Other_sequence (74)
Associated_featureWBsf654935
WBsf225289
Experimental_infoRNAi_result (23)
Expr_patternChronogram734
Expr2229
Expr7238
Expr1012073
Expr1032447
Expr1163018
Expr2015969
Expr2034204
Drives_constructWBCnstr00004145
WBCnstr00035322
Construct_productWBCnstr00035322
AntibodyWBAntibody00000550
WBAntibody00000552
WBAntibody00000553
WBAntibody00000554
Microarray_results (23)
Expression_clusterWBPaper00029359_1197
WBPaper00029359_1225
WBPaper00029359_1291
WBPaper00029359_1367
WBPaper00029359_1483
WBPaper00029359_1494
WBPaper00029359_1546
WBPaper00029359_1561
WBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032528:L3_enriched
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00038118:aak-2(gt33)_downregulated
WBPaper00038289:oocyte_protein
WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00045774:clk-1_downregulated
WBPaper00045974:NSM_enriched_DSN-treated_RNAseq
WBPaper00045974:NSM_enriched_totalRNA_RNAseq
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00047132:skn-1(RNAi)_downregulated_glp-1(ts)-dependent
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00050182:lmn-1(L535P)_downregulated
WBPaper00050193:cec-4(ok3124)_downregulated_L1
WBPaper00050412:cco-1(RNAi)_downregulated_N2
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053388:dauer_regulated_Cluster6
WBPaper00053615:SMO-1_target
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00055049:S.gordonii_downregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055648:germline_expressed
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056826:SGP_biased
WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057068:ints-4(RNAi)_upregulated
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00059664:srbc-48(ac23)_downregulated
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060459:bcat-1(RNAi)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061479:HDA-1_interacting_protein
WBPaper00061527:R07E4.5-skp-1_1608
WBPaper00061651:Germline_enriched
WBPaper00062156:jmjd-5(zr1234)_upregulated_germline
WBPaper00062159:hda-2(ok1479)_downregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062456:doxycycline_downregulated_CB4856_protein
WBPaper00062590:Aging_upregulated_neuron
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
WBPaper00064055:trl-1(cas1077)_downregulated_starved
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064201:SNA-1_interacting
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00064403:Heat-killed-E.Coli_upregulated
WBPaper00064716:paraquat_upregulated
WBPaper00064952:Day5_vs_Day1_upregulated_25C
WBPaper00064952:Day5_vs_L4_upregulated_20C
WBPaper00064952:Day5_vs_L4_upregulated_25C
WBPaper00064952:Day10_vs_Day1_upregulated_20C
WBPaper00064952:Day10_vs_Day1_upregulated_25C
WBPaper00064952:Day10_vs_L4_upregulated_20C
WBPaper00064952:Day10_vs_L4_upregulated_25C
WBPaper00065120:body-muscle-transcriptome
WBPaper00065258:anchor-cell_enriched
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4386_cluster_5_3
cgc4489_group_2
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00027342:alpha-Synuclein(WT)_upregulated
WBPaper00032948:FedUp
WBPaper00036123:Atrazine_regulated
WBPaper00036123:Fluoranthene_regulated
WBPaper00036286:Pattern_B
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_developing
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00042128:gei-8(ok1671)_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(23_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc6390]:intrinsic
Interaction (202)
Map_infoMapIIIPosition-0.534667Error0.000692
PositivePositive_cloneZK652Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005457
WBPaper00038491
WBPaper00040897
WBPaper00046427
WBPaper00046572
WBPaper00055090
RemarkLocus was previously incorrectly associated with Y71G12B.14 [krb 030219]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene