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WormBase Tree Display for Gene: WBGene00017120

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Name Class

WBGene00017120SMapS_parentSequenceE04A4
IdentityVersion2
NameCGC_nametctn-1Person_evidenceWBPerson1657
WBPerson14462
WBPerson14460
Sequence_nameE04A4.6
Molecular_nameE04A4.6
E04A4.6.1
CE46218
Other_nameCELE_E04A4.6Accession_evidenceNDBBX284604
Public_nametctn-1
DB_infoDatabaseAceViewgene4F510
WormQTLgeneWBGene00017120
WormFluxgeneWBGene00017120
NDBlocus_tagCELE_E04A4.6
PanthergeneCAEEL|WormBase=WBGene00017120|UniProtKB=O44478
familyPTHR14611
NCBIgene184035
RefSeqproteinNM_068227.4
TREEFAMTREEFAM_IDTF316522
TrEMBLUniProtAccO44478
UniProt_GCRPUniProtAccO44478
OMIMgene609863
613847
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
208 Dec 2011 14:44:24WBPerson2970Name_changeCGC_nametctn-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtctn
Allele (18)
StrainWBStrain00032915
RNASeq_FPKM (74)
GO_annotation00032516
00032517
00032518
00032519
Contained_in_operonCEOP4148
Ortholog (24)
Structured_descriptionAutomated_descriptionPredicted to be involved in cilium assembly. Predicted to be located in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome 13; Joubert syndrome 18; and orofaciodigital syndrome IV. Is an ortholog of human TCTN1 (tectonic family member 1) and TCTN3 (tectonic family member 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110987Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:24519)
DOID:0110982Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:26113)
DOID:0060374Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:24519)
Molecular_infoCorresponding_CDSE04A4.6
Corresponding_CDS_historyE04A4.6:wp227
Corresponding_transcriptE04A4.6.1
Other_sequenceACC09020_1
EY461619.1
Associated_featureWBsf651774
WBsf667904
Experimental_infoRNAi_resultWBRNAi00012682Inferred_automaticallyRNAi_primary
WBRNAi00043666Inferred_automaticallyRNAi_primary
Expr_patternExpr12582
Expr1013020
Expr1037353
Expr1147650
Expr2017365
Expr2035502
Construct_productWBCnstr00022310
Microarray_results (17)
Expression_clusterWBPaper00037946:LIN-39_interacting
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:BAG-neuron_embryo_enriched
WBPaper00037950:BAG-neuron_embryo_SelectivelyEnriched
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00042194:nhr-114(RNAi)_downregulated
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044260:1-methylnicotinamide_downregulated
WBPaper00044316:CH3HgCl_7.5uM_downregulated
WBPaper00045390:ubc-9(RNAi)_downregulated
WBPaper00046012:tdp-1(ok803)_upregulated
WBPaper00046121:ecdoderm_unique
WBPaper00048988:neuron_expressed
WBPaper00049498:npr-1(ur89)_regulated_4
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00051558:aging_regulated
WBPaper00053295:lin-22(icb38)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055137:S.maltophilia_upregulated
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056167:Cry5B_upregulated
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00057143:ztf-11(RNAi)_downregulated
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058969:RIS_depleted
WBPaper00059471:EGL-43_interacting
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:ADE
WBPaper00061340:ADF
WBPaper00061340:ADF_AWB
WBPaper00061340:ADL
WBPaper00061340:ADL_parent
WBPaper00061340:AFD
WBPaper00061340:ASE
WBPaper00061340:ASE_parent
WBPaper00061340:ASG
WBPaper00061340:ASG_AWA
WBPaper00061340:ASH
WBPaper00061340:ASI
WBPaper00061340:ASI_parent
WBPaper00061340:ASJ
WBPaper00061340:ASK
WBPaper00061340:ASK_parent
WBPaper00061340:AUA
WBPaper00061340:AWA
WBPaper00061340:AWB
WBPaper00061340:AWC
WBPaper00061340:BAG
WBPaper00061340:CEP
WBPaper00061340:IL1
WBPaper00061340:IL1_parent
WBPaper00061340:IL2
WBPaper00061340:Neuroblast_ADE_ADA
WBPaper00061340:Neuroblast_ASG_AWA
WBPaper00061340:Neuroblast_ASJ_AUA
WBPaper00061340:Neuroblast_HSN_PHB
WBPaper00061340:Neuroblast_URX_CEPDx
WBPaper00061340:OLL
WBPaper00061340:OLL_parent
WBPaper00061340:OLQ
WBPaper00061340:OLQ_parent
WBPaper00061340:URX
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061527:rab-28-jbts-14_9542
WBPaper00062103:neuron_enriched
WBPaper00062146:MOG-7-degron_2h_regulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062184:PA14_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065841:25_0
WBPaper00065841:25_1
WBPaper00066232:ash-2(RNAi)_upregulated_WT
WBPaper00066232:hsf-1(RNAi)_downregulated_ash-2
WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00027111:rrf-3(pk1426)_downregulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030985:Erwinia_carotovora_downregulated
WBPaper00030985:Serratia_marcesens_downregulated
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00036286:Pattern_F
WBPaper00039866:ClassComp_daf-19_downregulated
WBPaper00039866:SAM_daf-19_downregulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
WBPaper00053550:daf-19(m86)_downregulated_L1
InteractionWBInteraction000317863
WBInteraction000390963
Map_infoMapIVPosition0.770768
PositivePositive_cloneE04A4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00048761
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene