WormBase Tree Display for Gene: WBGene00014215

WBGene00014215 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 2
    Name: CGC_name: obr-3 Person_evidence: WBPerson1105
      Sequence_name: ZK1086.1
      Molecular_name: ZK1086.1a
        ZK1086.1a.1
        CE31672
        ZK1086.1b
        CE31673
        ZK1086.1b.1
      Other_name: CELE_ZK1086.1 Accession_evidence: NDB BX284606
      Public_name: obr-3
    DB_info: Database: AceView gene XO418
        WormQTL gene WBGene00014215
        WormFlux gene WBGene00014215
        NDB locus_tag CELE_ZK1086.1
        Panther gene CAEEL|WormBase=WBGene00014215|UniProtKB=Q8MPR9
          family PTHR10972
        NCBI gene 181495
        RefSeq protein NM_001392877.1
            NM_171794.7
        TREEFAM TREEFAM_ID TF312807
        TrEMBL UniProtAcc Q8MPR9
            G5EC19
        UniProt_GCRP UniProtAcc Q8MPR9
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Jul 2004 16:55:45 WBPerson1971 Name_change: CGC_name: obr-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: obr
    Allele: WBVar01499887
      WBVar01499519
      WBVar01499888
      WBVar00261862
      WBVar00261863
      WBVar01499710
      WBVar01981572
      WBVar01981573
      WBVar01981574
      WBVar01491434
      WBVar00217120
      WBVar00217121
      WBVar00217122
      WBVar00217123
      WBVar00217125
      WBVar00217126
      WBVar00217127
      WBVar01830835
      WBVar00217130
      WBVar01830836
      WBVar01203949
      WBVar01830837
      WBVar01203950
      WBVar01830838
      WBVar01830839
      WBVar01203951
      WBVar01830840
      WBVar01203952
      WBVar01203953
      WBVar01203954
      WBVar01203955
      WBVar01203956
      WBVar01203957
      WBVar00250105
      WBVar01203958
      WBVar01203959
      WBVar01489619
      WBVar01203960
      WBVar01203961
      WBVar01203962
      WBVar01203963
      WBVar01203964
      WBVar01203965
      WBVar01203966
      WBVar01203967
      WBVar01203968
      WBVar01203969
      WBVar01203970
      WBVar01203971
      WBVar01203972
      WBVar01203973
      WBVar01498835
      WBVar01203974
      WBVar01203975
      WBVar01203976
      WBVar01826021
      WBVar01203977
      WBVar01203978
      WBVar01203979
      WBVar02085878
      WBVar01203980
      WBVar01988114
      WBVar01203981
      WBVar01544681
      WBVar01203982
      WBVar01544682
      WBVar00278230
      WBVar01203983
      WBVar01544683
      WBVar01203984
      WBVar01203985
      WBVar01544684
      WBVar01203986
      WBVar01552462
      WBVar01544685
      WBVar01203987
      WBVar01552463
      WBVar01544686
      WBVar01203988
      WBVar01544687
      WBVar01552464
      WBVar01544688
      WBVar01552465
      WBVar01203989
      WBVar01552466
      WBVar01203990
      WBVar01544689
      WBVar01203991
      WBVar01203992
      WBVar01203993
      WBVar01203994
      WBVar01497014
      WBVar01203995
      WBVar01203996
      WBVar01203997
      WBVar01203998
      WBVar00522764
      WBVar01203999
      WBVar01204000
      WBVar00522765
      WBVar00522766
      WBVar01204001
      WBVar00522767
      WBVar01204002
      WBVar01204003
      WBVar00522768
      WBVar01488008
      WBVar01679227
      WBVar01204004
      WBVar00522769
      WBVar01204005
      WBVar01488009
      WBVar00522770
      WBVar01679228
      WBVar01204006
      WBVar00522771
      WBVar01488010
      WBVar01679229
      WBVar01204007
      WBVar01488011
      WBVar01679230
      WBVar00522772
      WBVar01204008
      WBVar01679231
      WBVar00522773
      WBVar01488012
      WBVar01679232
      WBVar00522774
      WBVar01204009
      WBVar01488013
      WBVar01679233
      WBVar00522775
      WBVar01204010
      WBVar01679234
      WBVar01204011
      WBVar00522776
      WBVar01204012
      WBVar00101462
      WBVar00522777
      WBVar01679235
      WBVar00101463
      WBVar01204013
      WBVar01679236
      WBVar00522778
      WBVar01204014
      WBVar00101464
      WBVar00522779
      WBVar00522780
      WBVar01204015
      WBVar00101465
      WBVar00522781
      WBVar00101466
      WBVar01204016
      WBVar00522782
      WBVar01204017
      WBVar01204018
      WBVar00522783
      WBVar01204019
      WBVar01204020
      WBVar02013786
      WBVar01204021
      WBVar01941785
      WBVar02049201
      WBVar01204022
      WBVar01941786
      WBVar01941787
      WBVar01204023
      WBVar01787720
      WBVar01787721
      WBVar01941788
      WBVar01204024
      WBVar01941789
      WBVar01204025
      WBVar01204026
      WBVar01941790
      WBVar01204027
      WBVar01955137
      WBVar01911323
      WBVar01955138
      WBVar02140455
      WBVar02140456
      WBVar01622063
      WBVar00266028
      WBVar00266029
      WBVar00256646
      WBVar01760024
      WBVar00266034
      WBVar00266035
      WBVar00084352
      WBVar00084353
      WBVar00084354
      WBVar00084355
      WBVar00084356
      WBVar00084357
      WBVar00084358
      WBVar00084359
      WBVar00084360
      WBVar00237222
      WBVar00237223
      WBVar00264408
      WBVar02005385
      WBVar02005386
      WBVar02075427
      WBVar02005387
      WBVar02005388
      WBVar01703853
      WBVar01472206
      WBVar01572680
      WBVar01703854
      WBVar01472207
      WBVar02072064
      WBVar02027598
      WBVar01901781
      WBVar01901782
      WBVar01498960
      WBVar01946201
      WBVar01500067
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (37)
    Paralog: WBGene00008832 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012930 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016331 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: obr-3 encodes two isoforms of a protein with an N-terminal pleckstrin domain and a C-terminal oxysterol-binding domain; OBR-3 has orthologs in Drosophila (CG5077) and humans (OSBPL8; OMIM:606736); OBR-3 binds the BMP receptor-associated molecule (BRAM) proteins BRA-1 and BRA-2; obr-3 is expressed in pharyngeal muscle, hypodermis, and several neurons; obr-3 is required for normally large body size, and the small body phenotype of obr-3(RNAi) animals is consistent with OBR-3 participating in TGF-beta signalling. Paper_evidence: WBPaper00004823
            WBPaper00012885
            WBPaper00012937
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 08 Nov 2010 00:00:00
      Automated_description: Predicted to enable cholesterol binding activity and sterol transporter activity. Involved in regulation of growth and transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and membrane. Expressed in hypodermis; neurons; and pharyngeal muscle cell. Is an ortholog of human OSBPL5 (oxysterol binding protein like 5) and OSBPL8 (oxysterol binding protein like 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1086.1a
      ZK1086.1b
    Corresponding_CDS_history: ZK1086.1:wp83
    Corresponding_transcript: ZK1086.1a.1
      ZK1086.1b.1
    Other_sequence (19)
    Associated_feature (15)
  Experimental_info (7)
  Map_info: Map: X Position: 14.9473 Error: 0.029025
    Positive: Positive_clone: ZK1086 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4859
        4827
        4961
    Pseudo_map_position
  Reference: WBPaper00010145
    WBPaper00030935
    WBPaper00031972
    WBPaper00038491
    WBPaper00053705
    WBPaper00055090
    WBPaper00060493
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene