WormBase Tree Display for Gene: WBGene00000411
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WBGene00000411 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | R06F6 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | cdl-1 | Person_evidence | WBPerson634 | |||||
Sequence_name | R06F6.1 | ||||||||
Molecular_name | R06F6.1 | ||||||||
R06F6.1.1 | |||||||||
CE51537 | |||||||||
Other_name | hbp | ||||||||
CELE_R06F6.1 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | cdl-1 | ||||||||
DB_info | Database | AceView | gene | 2L75 | |||||
WormQTL | gene | WBGene00000411 | |||||||
WormFlux | gene | WBGene00000411 | |||||||
NDB | locus_tag | CELE_R06F6.1 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000411|UniProtKB=Q09599 | |||||||
family | PTHR17408 | ||||||||
NCBI | gene | 174659 | |||||||
RefSeq | protein | NM_063919.8 | |||||||
SwissProt | UniProtAcc | Q09599 | |||||||
TREEFAM | TREEFAM_ID | TF316521 | |||||||
UniProt_GCRP | UniProtAcc | Q09599 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cdl | ||||||||
Allele | WBVar00275115 | Inferred_automatically | From strain object: SA4 | ||||||
WBVar00092685 | Inferred_automatically | From strain object: VC1004 | |||||||
WBVar01499702 | |||||||||
WBVar01499347 | |||||||||
WBVar01499348 | |||||||||
WBVar01498435 | |||||||||
WBVar00249778 | |||||||||
WBVar00552729 | |||||||||
WBVar00144853 | |||||||||
WBVar00144860 | |||||||||
WBVar00092286 | |||||||||
WBVar01826628 | |||||||||
WBVar00175399 | |||||||||
WBVar01477942 | |||||||||
WBVar01538610 | |||||||||
WBVar00764836 | |||||||||
WBVar00764837 | |||||||||
WBVar01498940 | |||||||||
WBVar00376932 | |||||||||
WBVar00764838 | |||||||||
WBVar00376933 | |||||||||
WBVar00764839 | |||||||||
WBVar00764840 | |||||||||
WBVar00376934 | |||||||||
WBVar00376935 | |||||||||
WBVar00764841 | |||||||||
WBVar00764842 | |||||||||
WBVar00376936 | |||||||||
WBVar00764843 | |||||||||
WBVar00764844 | |||||||||
WBVar00764845 | |||||||||
WBVar00764846 | |||||||||
WBVar00764847 | |||||||||
WBVar00764848 | |||||||||
WBVar00764849 | |||||||||
WBVar00764850 | |||||||||
WBVar00764851 | |||||||||
Legacy_information | [A Sugimoto] Cell Death Lethal. w37: (null) zygotic lethal, embryonic arrest with accumulated cell corpses, body elongation defect, pharynx not connected to buccal cavity. e2501, e2510: (possibly neomorphs) similar to w37, but more severe corpse accumulation and elongation defect. | ||||||||
Strain | WBStrain00022736 | ||||||||
WBStrain00033878 | |||||||||
WBStrain00036242 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (16) | |||||||||
Ortholog (35) | |||||||||
Structured_description | Concise_description | cdl-1 encodes a homolog of human hairpin (stem-loop) binding proteins (HBP/SLBP) that bind to the hairpin (stem-loop) structure in the 3' untranslated region (3' UTR) of histone mRNAs, and thus promote histone pre-mRNA processing and translation of mature histone mRNA; CDL-1 is required for normally high levels of histone gene expression, normal cell division during late larval development, embryonic viability, normal vulval morphogenesis, normally rapid apoptosis, and fertility; CDL-1 binds to the stem-loop structure in the 3' UTR of core-histone mRNA; the cdl-1 promoter is most active in dividing cells during embryogenesis and postembryonic development; both CDL-1 and human HBP contain a minimal RNA-binding domain (RBD) of roughly 73 amino acids that has no similarity with other known RNA-binding motifs. | Paper_evidence | WBPaper00004428 | |||||
WBPaper00005085 | |||||||||
WBPaper00005142 | |||||||||
WBPaper00013577 | |||||||||
Person_evidence | WBPerson1874 | ||||||||
Curator_confirmed | WBPerson13481 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables mRNA 3'-UTR binding activity. Involved in apoptotic process; embryo development; and mitotic chromosome condensation. Predicted to be located in cytoplasm. Predicted to be part of histone pre-mRNA 3'end processing complex. Expressed widely. Is an ortholog of human SLBP (stem-loop histone mRNA binding protein). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | R06F6.1 | |||||||
Corresponding_CDS_history | R06F6.1:wp252 | ||||||||
Corresponding_transcript | R06F6.1.1 | ||||||||
Other_sequence (18) | |||||||||
Associated_feature (12) | |||||||||
Experimental_info | RNAi_result | WBRNAi00082051 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00069364 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00009038 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00008237 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00034665 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00051393 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00026046 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00069365 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00082056 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00086822 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1840 | ||||||||
Expr10540 | |||||||||
Expr1028207 | |||||||||
Expr1030228 | |||||||||
Expr1155082 | |||||||||
Expr2009819 | |||||||||
Expr2028060 | |||||||||
Drives_construct | WBCnstr00010480 | ||||||||
WBCnstr00015525 | |||||||||
WBCnstr00037562 | |||||||||
Construct_product | WBCnstr00015525 | ||||||||
WBCnstr00037562 | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (193) | |||||||||
Interaction (122) | |||||||||
WBProcess | WBbiopr:00000014 | ||||||||
WBbiopr:00000015 | |||||||||
WBbiopr:00000036 | |||||||||
WBbiopr:00000098 | |||||||||
Map_info | Map | II | Position | 3.12577 | Error | 0.000223 | |||
Well_ordered | |||||||||
Positive | Positive_clone | R06F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
T19E10 | Person_evidence | WBPerson634 | |||||||
Mapping_data | Multi_point | 4880 | |||||||
Pos_neg_data | 10583 | ||||||||
10584 | |||||||||
10585 | |||||||||
10586 | |||||||||
Reference | WBPaper00004428 | ||||||||
WBPaper00005085 | |||||||||
WBPaper00005142 | |||||||||
WBPaper00011903 | |||||||||
WBPaper00012690 | |||||||||
WBPaper00016954 | |||||||||
WBPaper00017122 | |||||||||
WBPaper00017777 | |||||||||
WBPaper00019455 | |||||||||
WBPaper00022448 | |||||||||
WBPaper00023327 | |||||||||
WBPaper00025647 | |||||||||
WBPaper00025659 | |||||||||
WBPaper00026593 | |||||||||
WBPaper00030768 | |||||||||
WBPaper00031554 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00044501 | |||||||||
WBPaper00049397 | |||||||||
WBPaper00050681 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00059254 | |||||||||
Method | Gene |