WormBase Tree Display for WBProcess: WBbiopr:00000098
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| WBbiopr:00000098 | Public_name | Mitosis | |||
|---|---|---|---|---|---|
| Summary | Mitosis is part of the eukaryotic cell cycle and results in the production of two daughter cells each with a copy of the genome. The cell cycle itself is comprised of an interphase (made up of three stages G1, S, and G2) and the M (mitotic) phase. Cell growth, active transcription and translation, and DNA replication occur during interphase. During M phase duplicated DNA (chromatin) condense into sister chromatids (prophase); the nuclear envelop breaks down, kinetochore microtubles attach to the chromosomes and centrosomes are pushed to the poles of the growing spindle (prometaphase); the chromosomes are lined up on the metaphase plate (metaphase); sister chromatids are pulled to spindle poles at opposite ends of the cell (anaphase); the nuclear envelop is reformed and the chromatids decondense to chromatin (telophase); and the cell is cleaved into two by a contractile ring and the resolution of a cleavage furrow (cytokinesis). In some variant cell cycles nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. | ||||
| Related_topic | Specialisation_of | WBbiopr:00000016 | |||
| Involved_entity | Gene | WBGene00003367 | |||
| WBGene00000411 | Paper_evidence | WBPaper00005085 | |||
| Interaction | WBInteraction000540543 | ||||
| WBInteraction000540553 | |||||
| WBInteraction000540554 | |||||
| WBInteraction000540555 | |||||
| WBInteraction000540556 | |||||
| WBInteraction000556295 | |||||
| WBInteraction000556296 | |||||
| Reference | WBPaper00005085 |
