WormBase Tree Display for Gene: WBGene00017578

WBGene00017578 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 2
    Name: CGC_name: drl-1 Paper_evidence: WBPaper00045036
      Sequence_name: F18F11.5
      Molecular_name: F18F11.5
        F18F11.5.1
        CE48587
      Other_name: mekk-3 Paper_evidence: WBPaper00045036
        CELE_F18F11.5 Accession_evidence: NDB BX284604
      Public_name: drl-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:59 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 30 May 2014 11:12:36 WBPerson2970 Name_change: CGC_name: drl-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: drl
    Allele: WBVar01450070
      WBVar01450071
      WBVar01450072
      WBVar01450073
      WBVar01450074
      WBVar02133161
      WBVar02133162
      WBVar01831379
      WBVar01499166
      WBVar01646885
      WBVar01646886
      WBVar01646887
      WBVar01646888
      WBVar01646889
      WBVar01274479
      WBVar01710203
      WBVar01607456
      WBVar01607457
      WBVar01499384
      WBVar01499385
      WBVar00879628
      WBVar00879629
      WBVar00879630
      WBVar00879631
      WBVar00879632
      WBVar00879633
      WBVar00879634
      WBVar00879635
      WBVar00879636
      WBVar00879637
      WBVar00879638
      WBVar00879639
      WBVar00879640
      WBVar00879641
      WBVar00879642
      WBVar00879643
      WBVar01495908
      WBVar00879644
      WBVar00879645
      WBVar00879646
      WBVar00879647
      WBVar00879648
      WBVar00879649
      WBVar01984266
      WBVar00879650
      WBVar00879651
      WBVar01984267
      WBVar00879652
      WBVar00879653
      WBVar00879654
      WBVar00879655
      WBVar00879656
      WBVar00879657
      WBVar00879658
      WBVar00879659
      WBVar00879660
      WBVar00879661
      WBVar00879662
      WBVar01499608
      WBVar00879663
      WBVar00879664
      WBVar00879665
      WBVar00879666
      WBVar00879667
      WBVar00879668
      WBVar01495197
      WBVar00879669
      WBVar00879670
      WBVar00879671
      WBVar00879672
      WBVar00879673
      WBVar00879674
      WBVar00879675
      WBVar00879676
      WBVar00879677
      WBVar00879678
      WBVar00879679
      WBVar00879680
      WBVar00879681
      WBVar01499633
      WBVar02147169
      WBVar01499498
      WBVar01499499
      WBVar00415031
      WBVar00415032
      WBVar00415033
      WBVar00415034
      WBVar00415035
      WBVar00415036
      WBVar00415037
      WBVar01823380
      WBVar00415038
      WBVar00415039
      WBVar01499328
      WBVar00415040
      WBVar01499329
    Possibly_affected_by: WBVar02153185
      WBVar02159007
    Strain: WBStrain00055667
      WBStrain00055641
    RNASeq_FPKM (74)
    GO_annotation: 00083355
      00083356
      00122927
      00122928
      00122929
    Ortholog (18)
    Paralog (19)
    Structured_description: Concise_description: drl-1 encodes a protein kinase similar to the mammalian MEKK3-like kinase; DRL-1 functions in C. elegans to regulate dietary restriction-mediated longevity. Paper_evidence: WBPaper00045036
          Curator_confirmed: WBPerson1843
          Date_last_updated: 05 Aug 2014 00:00:00
      Automated_description: Predicted to enable ATP binding activity and protein kinase activity. Predicted to be located in membrane. Expressed in body wall musculature; neurons; seam cell; and vulval muscle. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F18F11.5
    Corresponding_transcript: F18F11.5.1
    Other_sequence: Acan_isotig15406
      FK804347.1
      CBC00121_1
    Associated_feature: WBsf995121
      WBsf995122
      WBsf1016535
      WBsf1016536
      WBsf227829
      WBsf227830
  Experimental_info: RNAi_result (26)
    Expr_pattern: Expr11696
      Expr16267
      Expr16268
      Expr1019421
      Expr1037549
      Expr1148935
      Expr2011090
      Expr2029326
    Drives_construct: WBCnstr00019316
      WBCnstr00027192
      WBCnstr00042868
    Construct_product: WBCnstr00027192
      WBCnstr00042868
    Microarray_results (16)
    Expression_cluster: WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045861:set-2(ok952)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048690:gonad-male-biased
      WBPaper00048690:male-Z1-Z4-daughter_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00053094:adr-2(ok735)_neuron_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055897:heat-shock_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:g1A
      WBPaper00061340:hyp3
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064716:paraquat_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_25
      WBPaper00025099:MA_specific
      WBPaper00025099:NI_specific
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_B
      WBPaper00026980:intestine_enriched
      WBPaper00028948:cep-1(gk138)+UV_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00055899:nitroguanidine_regulated
      [cgc6390]:Cluster_B
      [cgc6390]:Cluster_C
      [cgc6390]:herm_soma-enriched
    Interaction: WBInteraction000542596
      WBInteraction000542627
      WBInteraction000543104
      WBInteraction000543105
      WBInteraction000543113
  Map_info: Map: IV Position: -26.493
    Positive: Positive_clone: F18F11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (14)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene