WormBase Tree Display for Gene: WBGene00016266

WBGene00016266 SMap: S_parent: Sequence: C30F12
  Identity: Version: 2
    Name: CGC_name: idhg-2 Person_evidence: WBPerson1983
            WBPerson261
      Sequence_name: C30F12.7
      Molecular_name: C30F12.7
        C30F12.7.1
        CE16887
      Other_name: CELE_C30F12.7 Accession_evidence: NDB BX284601
      Public_name: idhg-2
    DB_info: Database: AceView gene 1H553
        WormQTL gene WBGene00016266
        WormFlux gene WBGene00016266
        NDB locus_tag CELE_C30F12.7
        Panther gene CAEEL|WormBase=WBGene00016266|UniProtKB=Q95YD8
          family PTHR11835
        NCBI gene 172430
        RefSeq protein NM_059588.8
        TREEFAM TREEFAM_ID TF315033
        TrEMBL UniProtAcc Q95YD8
        UniProt_GCRP UniProtAcc Q95YD8
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:57 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 08 Dec 2011 12:14:43 WBPerson2970 Name_change: CGC_name: idhg-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: idhg
    Allele: WBVar00260221
      WBVar00260222
      WBVar00093685
      WBVar00337286
      WBVar00337287
      WBVar00337288
      WBVar00337289
      WBVar01846489
      WBVar01499786
      WBVar01499054
      WBVar01283398
      WBVar00646920
      WBVar00646921
      WBVar00646922
      WBVar00646923
      WBVar00646924
      WBVar00646925
      WBVar00646926
      WBVar00646927
      WBVar00646928
      WBVar00646929
      WBVar00646930
      WBVar00646931
      WBVar00646932
      WBVar01498959
    Strain: WBStrain00032631
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (39)
    Paralog: WBGene00007993 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009440 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009664 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: C30F12.7 encodes the C. elegans homolog of the gamma subunit of an NAD+-dependent mitochondrial isocitrate dehydrogenase; by homology, the product of C30F12.7 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate as part of the citric acid cycle. Curator_confirmed: WBPerson1843
          Date_last_updated: 26 Oct 2011 00:00:00
      Automated_description: Predicted to enable NAD binding activity and magnesium ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Is an ortholog of human IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C30F12.7
    Corresponding_transcript: C30F12.7.1
    Other_sequence (69)
    Associated_feature: WBsf984042
      WBsf984043
      WBsf217927
  Experimental_info: RNAi_result: WBRNAi00084390 Inferred_automatically: RNAi_primary
      WBRNAi00029360 Inferred_automatically: RNAi_primary
      WBRNAi00041552 Inferred_automatically: RNAi_primary
      WBRNAi00003042 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027079
      Expr1145570
      Expr2012674
      Expr2030910
    Drives_construct: WBCnstr00028205
    Construct_product: WBCnstr00028205
    Microarray_results (19)
    Expression_cluster: WBPaper00028451:Abundant_spermatogenesis_enriched
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:down_in_alg-1
      WBPaper00032425:down_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00037950:bodywall-muscle_embryo_enriched
      WBPaper00037950:bodywall-muscle_embryo_SelectivelyEnriched
      WBPaper00040420:ALM_PLM_enriched
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Spermatogenic
      WBPaper00045774:clk-1_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049626:UNC-75_target
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050686:glp-1(e2141)_upregulated
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051352:Long-Term-Association-Memory_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056218:daf-16(mu86)_upregulated_Day3
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056855:his-72(uge40)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060634:unc-120(st364)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061040:FW1256_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061405:S.aureus_downregulated_starvation
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064201:SNA-3_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064992:Capsaicin_downregulated
      WBPaper00064992:Eugenol_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:4_1
      WBPaper00065841:4_2
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:38_1
      WBPaper00065841:38_3
      WBPaper00065841:143_0
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_2_5
      cgc4489_group_20
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00032062:age_regulated_genes
      WBPaper00032948:StarveUp2
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_C
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040963:Q50_up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:Cluster_A
    Interaction (186)
  Map_info: Map: I Position: 1.58364
    Positive: Positive_clone: C30F12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027145
    WBPaper00028451
    WBPaper00038491
    WBPaper00051770
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene