WormBase Tree Display for Gene: WBGene00022759

WBGene00022759 SMap: S_parent: Sequence: ZK546
  Identity: Version: 1
    Name: Sequence_name: ZK546.2
      Molecular_name: ZK546.2a
        ZK546.2a.1
        CE36076
        ZK546.2b
        CE43764
        ZK546.2b.1
        ZK546.2b.2
        ZK546.2c
      Other_name: CELE_ZK546.2 Accession_evidence: NDB BX284602
      Public_name: ZK546.2
    DB_info: Database: AceView gene 2F237
        WormQTL gene WBGene00022759
        WormFlux gene WBGene00022759
        NDB locus_tag CELE_ZK546.2
        Panther gene CAEEL|WormBase=WBGene00022759|UniProtKB=Q23526
          family PTHR48051
        NCBI gene 173855
        RefSeq protein NR_151581.1
            NM_170985.5
            NM_001393057.1
        TrEMBL UniProtAcc Q23526
            Q95PW8
        UniProt_GCRP UniProtAcc Q23526
        RNAcentral URSid URS0000CBFF7A
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (37)
    RNASeq_FPKM (74)
    Contained_in_operon: CEOP2690
    Ortholog (26)
    Paralog: WBGene00003068 Caenorhabditis elegans From_analysis: Panther
      WBGene00002632 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004929 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009647 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015779 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021533 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Enriched in several structures, including ADE sheath cell; PLM; anterior ganglion; germ line; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Zidovudine; paraquat; and Hydrolyzable Tannins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat, typical subtype; Leucine Rich Repeat; Leucine-rich repeat; Leucine-rich repeat domain superfamily; and Leucine rich repeat. Is an ortholog of human LRRC57 (leucine rich repeat containing 57). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK546.2a
      ZK546.2b
    Corresponding_CDS_history: ZK546.2a:wp112
      ZK546.2b:wp203
      ZK546.2c:wp261
    Corresponding_transcript: ZK546.2c
      ZK546.2a.1
      ZK546.2b.1
      ZK546.2b.2
    Other_sequence (20)
    Associated_feature: WBsf644147
      WBsf644148
      WBsf644149
      WBsf644150
      WBsf644151
      WBsf657548
      WBsf987748
      WBsf221206
  Experimental_info: RNAi_result: WBRNAi00022052 Inferred_automatically: RNAi_primary
      WBRNAi00059506 Inferred_automatically: RNAi_primary
      WBRNAi00022053 Inferred_automatically: RNAi_primary
      WBRNAi00001102 Inferred_automatically: RNAi_primary
      WBRNAi00038332 Inferred_automatically: RNAi_primary
      WBRNAi00061964 Inferred_automatically: RNAi_primary
      WBRNAi00095828 Inferred_automatically: RNAi_primary
      WBRNAi00062490 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1026776
      Expr1040062
      Expr1162922
      Expr2008869
      Expr2027102
    Drives_construct: WBCnstr00023997
    Construct_product: WBCnstr00023997
    Microarray_results (37)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055827:pfd-6(gk493446)_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060886:spr-5(by101)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061340:ADEsh
      WBPaper00061340:CEPsh
      WBPaper00061340:CEPso
      WBPaper00061340:ILsh_OLLsh_OLQsh
      WBPaper00061340:ILso
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061527:F31C3.4_6048-cutc-1_15804
      WBPaper00061527:lst-4_22151-F46F11.6_12556
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00062590:Aging_upregulated_coelomocyte
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064716:paraquat_upregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      cgc4489_group_5
      WBPaper00025032:cluster_100
      WBPaper00025032:cluster_176
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:TA200_down
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_0.2mM_Down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:cluster_6
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(122_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MDE
      [cgc5767]:expression_class_MD_pd(23_min)
      [cgc5767]:expression_class_MD_pd(41_min)
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_E
      [cgc6390]:mixed_oogenesis-somatic
      [cgc6390]:oogenesis-enriched
    Interaction: WBInteraction000197445
      WBInteraction000280346
      WBInteraction000313845
      WBInteraction000367173
      WBInteraction000576468
  Map_info: Positive: Positive_clone: ZK546 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II -2.73082
  Reference: WBPaper00038491
    WBPaper00041771
    WBPaper00055090
  Method: Gene