WormBase Tree Display for Gene: WBGene00022642
expand all nodes | collapse all nodes | view schema
WBGene00022642 | SMap | S_parent | Sequence | ZK6 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | lipl-5 | Person_evidence | WBPerson3759 | |||
WBPerson7490 | |||||||
WBPerson545 | |||||||
Sequence_name | ZK6.7 | ||||||
Molecular_name | ZK6.7a | ||||||
ZK6.7a.1 | |||||||
CE18444 | |||||||
ZK6.7c | |||||||
CE50798 | |||||||
ZK6.7d | |||||||
CE50743 | |||||||
ZK6.7b | |||||||
ZK6.7c.1 | |||||||
ZK6.7d.1 | |||||||
Other_name | CELE_ZK6.7 | Accession_evidence | NDB | BX284605 | |||
Public_name | lipl-5 | ||||||
DB_info | Database (13) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | lipl | ||||||
Allele (47) | |||||||
Strain | WBStrain00033248 | ||||||
WBStrain00037811 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (14) | |||||||
Ortholog (66) | |||||||
Paralog | WBGene00008510 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00009773 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00010062 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00013050 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00019376 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00020016 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00021963 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | lipl-5 encodes a lipase; lipl-5 is expressed in the intestine and its expression is negatively regulated in well-fed animals by MXL-3; lipl-5 expression is induced upon bacterial infection. | Paper_evidence | WBPaper00005382 | |||
WBPaper00042295 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 19 Jun 2013 00:00:00 | ||||||
Automated_description | Predicted to enable hydrolase activity, acting on ester bonds. Involved in defense response to Gram-negative bacterium; lipid homeostasis; and triglyceride catabolic process. Located in lysosome. Expressed in coelomocyte and intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0080217 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||
DOID:14502 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||
DOID:14497 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||
DOID:0060717 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:23452) | ||||
Molecular_info | Corresponding_CDS | ZK6.7a | |||||
ZK6.7c | |||||||
ZK6.7d | |||||||
Corresponding_CDS_history | ZK6.7b:wp248 | ||||||
Corresponding_transcript (4) | |||||||
Other_sequence (34) | |||||||
Associated_feature | WBsf999148 | ||||||
WBsf1019064 | |||||||
WBsf231319 | |||||||
WBsf231320 | |||||||
WBsf231321 | |||||||
Experimental_info | RNAi_result (12) | ||||||
Expr_pattern | Expr1967 | ||||||
Expr14545 | |||||||
Expr14546 | |||||||
Expr1010508 | |||||||
Expr1162960 | |||||||
Expr2013207 | |||||||
Expr2031439 | |||||||
Drives_construct | WBCnstr00041084 | ||||||
Construct_product | WBCnstr00041084 | ||||||
Microarray_results (23) | |||||||
Expression_cluster (289) | |||||||
Interaction (38) | |||||||
WBProcess | WBbiopr:00000039 | ||||||
Map_info | Map | V | Position | -20 | |||
Positive | Positive_clone | ZK6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (12) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |