WormBase Tree Display for Gene: WBGene00008510

WBGene00008510 SMap: S_parent: Sequence: F01G10
  Identity: Version: 2
    Name: CGC_name: lipl-7 Person_evidence: WBPerson3759
            WBPerson7490
            WBPerson545
      Sequence_name: F01G10.7
      Molecular_name: F01G10.7
        F01G10.7.1
        CE40352
      Other_name: CELE_F01G10.7 Accession_evidence: NDB BX284604
      Public_name: lipl-7
    DB_info: Database: AceView gene 4L4
        WormQTL gene WBGene00008510
        WormFlux gene WBGene00008510
        NDB locus_tag CELE_F01G10.7
        Panther gene CAEEL|WormBase=WBGene00008510|UniProtKB=O17766
          family PTHR11005
        NCBI gene 184068
        RefSeq protein NM_069476.6
        TrEMBL UniProtAcc O17766
        UniProt_GCRP UniProtAcc O17766
        OMIM gene 613497
            613924
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 19 Jul 2010 13:43:13 WBPerson2970 Name_change: CGC_name: lipl-7
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lipl
    Allele (33)
    RNASeq_FPKM (74)
    GO_annotation: 00030661
      00030662
      00116409
      00116410
    Ortholog (45)
    Paralog: WBGene00009773 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019376 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00022642 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010062 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00021963 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00020016 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00013050 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080217 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6617)
      DOID:14502 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6617)
      DOID:14497 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6617)
      DOID:0060717 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23452)
  Molecular_info: Corresponding_CDS: F01G10.7
    Corresponding_CDS_history: F01G10.7:wp162
    Corresponding_transcript: F01G10.7.1
    Other_sequence (32)
    Associated_feature: WBsf652118
      WBsf668218
      WBsf668219
      WBsf230705
  Experimental_info: RNAi_result: WBRNAi00030553 Inferred_automatically: RNAi_primary
      WBRNAi00102889 Inferred_automatically: RNAi_primary
      WBRNAi00043769 Inferred_automatically: RNAi_primary
      WBRNAi00012749 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1029220
      Expr1033702
      Expr1147747
      Expr2013209
      Expr2031441
    Drives_construct: WBCnstr00032910
    Construct_product: WBCnstr00032910
    Microarray_results (22)
    Expression_cluster (145)
    Interaction: WBInteraction000041952
      WBInteraction000041957
      WBInteraction000110782
      WBInteraction000110783
      WBInteraction000573655
      WBInteraction000574437
  Map_info: Map: IV Position: 4.56337
    Positive: Positive_clone: F01G10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00045355
    WBPaper00055090
    WBPaper00059755
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene