WormBase Tree Display for Gene: WBGene00022642
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| WBGene00022642 | SMap | S_parent | Sequence | ZK6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | lipl-5 | Person_evidence | WBPerson3759 | |||||
| WBPerson7490 | |||||||||
| WBPerson545 | |||||||||
| Sequence_name | ZK6.7 | ||||||||
| Molecular_name | ZK6.7a | ||||||||
| ZK6.7a.1 | |||||||||
| CE18444 | |||||||||
| ZK6.7c | |||||||||
| CE50798 | |||||||||
| ZK6.7d | |||||||||
| CE50743 | |||||||||
| ZK6.7b | |||||||||
| ZK6.7c.1 | |||||||||
| ZK6.7d.1 | |||||||||
| Other_name | CELE_ZK6.7 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | lipl-5 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:06 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 19 Jul 2010 13:43:13 | WBPerson2970 | Name_change | CGC_name | lipl-5 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lipl | ||||||||
| Allele (47) | |||||||||
| Strain | WBStrain00033248 | ||||||||
| WBStrain00037811 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (66) | |||||||||
| Paralog | WBGene00008510 | Caenorhabditis elegans | From_analysis (3) | ||||||
| WBGene00009773 | Caenorhabditis elegans | From_analysis (3) | |||||||
| WBGene00010062 | Caenorhabditis elegans | From_analysis (4) | |||||||
| WBGene00013050 | Caenorhabditis elegans | From_analysis (3) | |||||||
| WBGene00019376 | Caenorhabditis elegans | From_analysis (3) | |||||||
| WBGene00020016 | Caenorhabditis elegans | From_analysis (4) | |||||||
| WBGene00021963 | Caenorhabditis elegans | From_analysis (3) | |||||||
| Structured_description | Concise_description | lipl-5 encodes a lipase; lipl-5 is expressed in the intestine and its expression is negatively regulated in well-fed animals by MXL-3; lipl-5 expression is induced upon bacterial infection. | Paper_evidence | WBPaper00005382 | |||||
| WBPaper00042295 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 19 Jun 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable hydrolase activity, acting on ester bonds. Involved in defense response to Gram-negative bacterium; lipid homeostasis; and triglyceride catabolic process. Located in lysosome. Expressed in coelomocyte and intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080217 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||
| DOID:14502 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||||
| DOID:14497 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||||
| DOID:0060717 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:23452) | ||||||
| Molecular_info | Corresponding_CDS | ZK6.7a | |||||||
| ZK6.7c | |||||||||
| ZK6.7d | |||||||||
| Corresponding_CDS_history | ZK6.7b:wp248 | ||||||||
| Corresponding_transcript | ZK6.7b | ||||||||
| ZK6.7a.1 | |||||||||
| ZK6.7c.1 | |||||||||
| ZK6.7d.1 | |||||||||
| Other_sequence (34) | |||||||||
| Associated_feature | WBsf999148 | ||||||||
| WBsf1019064 | |||||||||
| WBsf231319 | |||||||||
| WBsf231320 | |||||||||
| WBsf231321 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr1967 | ||||||||
| Expr14545 | |||||||||
| Expr14546 | |||||||||
| Expr1010508 | |||||||||
| Expr1162960 | |||||||||
| Expr2013207 | |||||||||
| Expr2031439 | |||||||||
| Drives_construct | WBCnstr00041084 | ||||||||
| Construct_product | WBCnstr00041084 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (289) | |||||||||
| Interaction (38) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| Map_info | Map | V | Position | -20 | |||||
| Positive | Positive_clone | ZK6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
