WormBase Tree Display for Gene: WBGene00022642
expand all nodes | collapse all nodes | view schema
WBGene00022642 | SMap | S_parent | Sequence | ZK6 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | lipl | |||||
Allele (47) | ||||||
Strain | WBStrain00033248 | |||||
WBStrain00037811 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (14) | ||||||
Ortholog (66) | ||||||
Paralog | WBGene00008510 | Caenorhabditis elegans | From_analysis | TreeFam | ||
Panther | ||||||
WormBase-Compara | ||||||
WBGene00009773 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | ||||||
WormBase-Compara | ||||||
WBGene00010062 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Inparanoid_8 | ||||||
Panther | ||||||
WormBase-Compara | ||||||
WBGene00013050 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | ||||||
WormBase-Compara | ||||||
WBGene00019376 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | ||||||
WormBase-Compara | ||||||
WBGene00020016 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Inparanoid_8 | ||||||
Panther | ||||||
WormBase-Compara | ||||||
WBGene00021963 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | ||||||
WormBase-Compara | ||||||
Structured_description | Concise_description | lipl-5 encodes a lipase; lipl-5 is expressed in the intestine and its expression is negatively regulated in well-fed animals by MXL-3; lipl-5 expression is induced upon bacterial infection. | Paper_evidence | WBPaper00005382 | ||
WBPaper00042295 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 19 Jun 2013 00:00:00 | |||||
Automated_description | Predicted to enable hydrolase activity, acting on ester bonds. Involved in defense response to Gram-negative bacterium; lipid homeostasis; and triglyceride catabolic process. Located in lysosome. Expressed in coelomocyte and intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:0080217 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | |
DOID:14502 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | |||
DOID:14497 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | |||
DOID:0060717 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:23452) | |||
Molecular_info | Corresponding_CDS | ZK6.7a | ||||
ZK6.7c | ||||||
ZK6.7d | ||||||
Corresponding_CDS_history | ZK6.7b:wp248 | |||||
Corresponding_transcript (4) | ||||||
Other_sequence (34) | ||||||
Associated_feature | WBsf999148 | |||||
WBsf1019064 | ||||||
WBsf231319 | ||||||
WBsf231320 | ||||||
WBsf231321 | ||||||
Experimental_info | RNAi_result (12) | |||||
Expr_pattern | Expr1967 | |||||
Expr14545 | ||||||
Expr14546 | ||||||
Expr1010508 | ||||||
Expr1162960 | ||||||
Expr2013207 | ||||||
Expr2031439 | ||||||
Drives_construct | WBCnstr00041084 | |||||
Construct_product | WBCnstr00041084 | |||||
Microarray_results (23) | ||||||
Expression_cluster (289) | ||||||
Interaction (38) | ||||||
WBProcess | WBbiopr:00000039 | |||||
Map_info | Map | V | Position | -20 | ||
Positive | Positive_clone | ZK6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference (12) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |