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WormBase Tree Display for Gene: WBGene00022642

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Name Class

WBGene00022642SMapS_parentSequenceZK6
IdentityVersion2
NameCGC_namelipl-5Person_evidenceWBPerson3759
WBPerson7490
WBPerson545
Sequence_nameZK6.7
Molecular_nameZK6.7a
ZK6.7a.1
CE18444
ZK6.7c
CE50798
ZK6.7d
CE50743
ZK6.7b
ZK6.7c.1
ZK6.7d.1
Other_nameCELE_ZK6.7Accession_evidenceNDBBX284605
Public_namelipl-5
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:06WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
219 Jul 2010 13:43:13WBPerson2970Name_changeCGC_namelipl-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlipl
AlleleWBVar00094550Inferred_automaticallyFrom strain object: RB2573
WBVar02149123Inferred_automaticallyFrom strain object: VC3788
WBVar02135553
WBVar01499528
WBVar01499167
WBVar01457478
WBVar01457479
WBVar01457480
WBVar01457481
WBVar01457482
WBVar00447638
WBVar00447639
WBVar00447640
WBVar00447641
WBVar00447642
WBVar00447643
WBVar01499740
WBVar01499775
WBVar00979112
WBVar00979113
WBVar01735037
WBVar00979114
WBVar00979115
WBVar00979116
WBVar00979117
WBVar00979118
WBVar00979119
WBVar00979120
WBVar00979121
WBVar00979122
WBVar02121626
WBVar00979123
WBVar00979124
WBVar00979125
WBVar00979126
WBVar02031486
WBVar00979127
WBVar00979128
WBVar00979129
WBVar00979130
WBVar00979131
WBVar00979132
WBVar01773375
WBVar01773376
WBVar01773377
WBVar01773378
WBVar02151414
StrainWBStrain00033248
WBStrain00037811
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (66)
ParalogWBGene00008510Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00009773Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00010062Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00013050Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00019376Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00020016Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00021963Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionlipl-5 encodes a lipase; lipl-5 is expressed in the intestine and its expression is negatively regulated in well-fed animals by MXL-3; lipl-5 expression is induced upon bacterial infection.Paper_evidenceWBPaper00005382
WBPaper00042295
Curator_confirmedWBPerson1843
Date_last_updated19 Jun 2013 00:00:00
Automated_descriptionPredicted to enable hydrolase activity, acting on ester bonds. Involved in defense response to Gram-negative bacterium; lipid homeostasis; and triglyceride catabolic process. Located in lysosome. Expressed in coelomocyte and intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080217Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6617)
DOID:14502Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6617)
DOID:14497Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6617)
DOID:0060717Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:23452)
Molecular_infoCorresponding_CDSZK6.7a
ZK6.7c
ZK6.7d
Corresponding_CDS_historyZK6.7b:wp248
Corresponding_transcriptZK6.7b
ZK6.7a.1
ZK6.7c.1
ZK6.7d.1
Other_sequence (34)
Associated_featureWBsf999148
WBsf1019064
WBsf231319
WBsf231320
WBsf231321
Experimental_infoRNAi_result (12)
Expr_patternExpr1967
Expr14545
Expr14546
Expr1010508
Expr1162960
Expr2013207
Expr2031439
Drives_constructWBCnstr00041084
Construct_productWBCnstr00041084
Microarray_results (23)
Expression_cluster (289)
Interaction (38)
WBProcessWBbiopr:00000039
Map_infoMapVPosition-20
PositivePositive_cloneZK6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene