WormBase Tree Display for Gene: WBGene00022199
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| WBGene00022199 | SMap | S_parent | Sequence | Y71H10A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | pfk-1.1 | Person_evidence | WBPerson3194 | |||||
| Sequence_name | Y71H10A.1 | ||||||||
| Molecular_name | Y71H10A.1a | ||||||||
| Y71H10A.1a.1 | |||||||||
| CE28266 | |||||||||
| Y71H10A.1b | |||||||||
| Other_name | pfk-1 | Person_evidence | WBPerson261 | ||||||
| CELE_Y71H10A.1 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | pfk-1.1 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 28 Sep 2012 14:29:00 | WBPerson2970 | Name_change | CGC_name | pfk-1 | ||||
| 3 | 03 Mar 2014 14:12:13 | WBPerson2970 | Name_change | CGC_name | pfk-1.1 | ||||
| Other_name | pfk-1 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pfk | ||||||||
| Allele (73) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (33) | |||||||||
| Ortholog (58) | |||||||||
| Paralog | WBGene00008230 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | pfk-1.1 encodes two isoforms of a 6-phosphofructokinase (E.C. 2.7.1.11), paralogous to PFK-1.2; pfk-1.1 is an essential gene, and expressed in proximal germline and in several larval and adult tissues (including neurons, hypodermis, and pharyngeal muscle). | Paper_evidence | WBPaper00004651 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00027758 | |||||||||
| WBPaper00028588 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 24 Feb 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Expressed in germ line; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type) and PFKM (phosphofructokinase, muscle). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:11721 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8877) | ||||
| Molecular_info | Corresponding_CDS | Y71H10A.1a | |||||||
| Corresponding_CDS_history | Y71H10A.1b:wp129 | ||||||||
| Y71H10A.1b:wp245 | |||||||||
| Corresponding_transcript | Y71H10A.1b | ||||||||
| Y71H10A.1a.1 | |||||||||
| Other_sequence (124) | |||||||||
| Associated_feature | WBsf718535 | ||||||||
| WBsf1004484 | |||||||||
| WBsf235423 | |||||||||
| WBsf235424 | |||||||||
| WBsf235425 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00021365 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00001724 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00037787 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058226 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00023148 | ||||||||
| WBCnstr00042042 | |||||||||
| Construct_product | WBCnstr00042042 | ||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (162) | |||||||||
| Interaction (92) | |||||||||
| Map_info | Map | X | Position | -12.6701 | |||||
| Positive | Positive_clone | Y71H10A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
