WormBase Tree Display for Gene: WBGene00008230
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| WBGene00008230 | SMap | S_parent | Sequence | C50F4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | pfk-1.2 | Person_evidence | WBPerson3194 | |||||
| Sequence_name | C50F4.2 | ||||||||
| Molecular_name | C50F4.2 | ||||||||
| C50F4.2.1 | |||||||||
| CE05467 | |||||||||
| Other_name | pfk-2 | Person_evidence | WBPerson261 | ||||||
| CELE_C50F4.2 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | pfk-1.2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 28 Sep 2012 14:29:00 | WBPerson2970 | Name_change | CGC_name | pfk-2 | ||||
| 3 | 03 Mar 2014 14:12:13 | WBPerson2970 | Name_change | CGC_name | pfk-1.2 | ||||
| Other_name | pfk-2 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pfk | ||||||||
| Allele (37) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (29) | |||||||||
| Ortholog (49) | |||||||||
| Paralog | WBGene00022199 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | pfk-1.2 encodes a 6-phosphofructokinase (E.C. 2.7.1.11), paralogous to PFK-1.1; pfk-1.2 is required for fertility, full body size, and normally rapid growth in mass RNAi assays; pfk-1.2 transcripts are enriched during spermatogenesis. | Paper_evidence | WBPaper00004651 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00006390 | |||||||||
| WBPaper00028588 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 24 Feb 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type); PFKM (phosphofructokinase, muscle); and PFKP (phosphofructokinase, platelet). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:11721 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8877) | ||||
| Molecular_info | Corresponding_CDS | C50F4.2 | |||||||
| Corresponding_transcript | C50F4.2.1 | ||||||||
| Other_sequence (20) | |||||||||
| Associated_feature | WBsf1000929 | ||||||||
| WBsf1020195 | |||||||||
| WBsf232263 | |||||||||
| WBsf232264 | |||||||||
| WBsf232265 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00030042 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00002413 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012235 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042942 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1013542 | ||||||||
| Expr1146911 | |||||||||
| Expr2014848 | |||||||||
| Expr2033083 | |||||||||
| Drives_construct | WBCnstr00033133 | ||||||||
| Construct_product | WBCnstr00033133 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (169) | |||||||||
| Interaction | WBInteraction000218529 | ||||||||
| WBInteraction000242562 | |||||||||
| WBInteraction000281652 | |||||||||
| WBInteraction000323206 | |||||||||
| WBInteraction000345736 | |||||||||
| WBInteraction000435409 | |||||||||
| WBInteraction000447267 | |||||||||
| WBInteraction000453668 | |||||||||
| WBInteraction000454498 | |||||||||
| Map_info | Map | V | Position | 2.04518 | |||||
| Positive | Positive_clone | C50F4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026800 | ||||||||
| WBPaper00027145 | |||||||||
| WBPaper00028498 | |||||||||
| WBPaper00029292 | |||||||||
| WBPaper00031648 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041537 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
