WormBase Tree Display for Gene: WBGene00022199
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WBGene00022199 | SMap | S_parent | Sequence | Y71H10A | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | pfk | |||||
Allele (73) | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (33) | ||||||
Ortholog (58) | ||||||
Paralog | WBGene00008230 | Caenorhabditis elegans | From_analysis | Panther | ||
WormBase-Compara | ||||||
Structured_description | Concise_description | pfk-1.1 encodes two isoforms of a 6-phosphofructokinase (E.C. 2.7.1.11), paralogous to PFK-1.2; pfk-1.1 is an essential gene, and expressed in proximal germline and in several larval and adult tissues (including neurons, hypodermis, and pharyngeal muscle). | Paper_evidence | WBPaper00004651 | ||
WBPaper00005654 | ||||||
WBPaper00025054 | ||||||
WBPaper00027758 | ||||||
WBPaper00028588 | ||||||
Curator_confirmed | WBPerson1843 | |||||
WBPerson1823 | ||||||
WBPerson567 | ||||||
Date_last_updated | 24 Feb 2014 00:00:00 | |||||
Automated_description | Predicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Expressed in germ line; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type) and PFKM (phosphofructokinase, muscle). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:11721 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8877) | |
Molecular_info | Corresponding_CDS | Y71H10A.1a | ||||
Corresponding_CDS_history | Y71H10A.1b:wp129 | |||||
Y71H10A.1b:wp245 | ||||||
Corresponding_transcript | Y71H10A.1b | |||||
Y71H10A.1a.1 | ||||||
Other_sequence (124) | ||||||
Associated_feature | WBsf718535 | |||||
WBsf1004484 | ||||||
WBsf235423 | ||||||
WBsf235424 | ||||||
WBsf235425 | ||||||
Experimental_info | RNAi_result | WBRNAi00021365 | Inferred_automatically | RNAi_primary | ||
WBRNAi00001724 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00037787 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00058226 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern (11) | ||||||
Drives_construct | WBCnstr00023148 | |||||
WBCnstr00042042 | ||||||
Construct_product | WBCnstr00042042 | |||||
Microarray_results (31) | ||||||
Expression_cluster (162) | ||||||
Interaction (92) | ||||||
Map_info | Map | X | Position | -12.6701 | ||
Positive | Positive_clone | Y71H10A | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference (16) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |