WormBase Tree Display for Gene: WBGene00020307
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WBGene00020307 | SMap | S_parent | Sequence | T07D3 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Allele (167) | |||||||
Strain | WBStrain00031550 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00001837 | ||||||
Ortholog (57) | |||||||
Paralog | WBGene00011554 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00017877 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
WBGene00020924 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00021249 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00020309 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
WBGene00020308 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
WBGene00020927 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00045475 | Caenorhabditis elegans | From_analysis | Panther | ||||
Structured_description | Concise_description | T07D3.4 is orthologous to the human gene, Fukutin (FKTN, also called FCMD). | Paper_evidence | WBPaper00038491 | |||
Curator_confirmed | WBPerson324 | ||||||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 07 Jun 2012 00:00:00 | ||||||
Automated_description | Predicted to be involved in protein glycosylation. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0050560 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||
DOID:0050559 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
DOID:0110443 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
DOID:9884 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
DOID:0112379 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
DOID:0110296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
DOID:0110444 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
DOID:0110284 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3622) | ||||
Disease_relevance | The human ortholog of elegans TO7D3.4, Fukutin, is required for normal glycosylation of the cell surface laminin receptor, alpha-dystroglycan; mutations in Fukutin cause cardiomyopathy and Fukuyama-type congenital muscular dystrophy (FCMD), an inherited condition that predominantly affects the muscles, brain, and eyes, due to weakness and wasting of skeletal muscles. | Homo sapiens | Accession_evidence | OMIM | 611615 | ||
253800 | |||||||
613152 | |||||||
611588 | |||||||
607440 | |||||||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 11 Jun 2012 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T07D3.4a | |||||
T07D3.4b | |||||||
Corresponding_transcript | T07D3.4a.1 | ||||||
T07D3.4b.1 | |||||||
Other_sequence | Oden_isotig15156 | ||||||
Oden_isotig21890 | |||||||
Dviv_isotig31365 | |||||||
Associated_feature | WBsf643929 | ||||||
WBsf643930 | |||||||
WBsf986513 | |||||||
WBsf986514 | |||||||
WBsf986515 | |||||||
WBsf1011453 | |||||||
WBsf1011454 | |||||||
WBsf220796 | |||||||
Experimental_info | RNAi_result | WBRNAi00035302 | Inferred_automatically | RNAi_primary | |||
WBRNAi00052752 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00018361 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00115898 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1013786 | ||||||
Expr1038847 | |||||||
Expr1156361 | |||||||
Expr2005965 | |||||||
Expr2024181 | |||||||
Drives_construct | WBCnstr00025231 | ||||||
Construct_product | WBCnstr00025231 | ||||||
Microarray_results (15) | |||||||
Expression_cluster (148) | |||||||
Interaction | WBInteraction000389723 | ||||||
WBInteraction000446865 | |||||||
Map_info | Positive | Positive_clone | T07D3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Interpolated_map_position | II | -15.5897 | |||||
Reference | WBPaper00038491 | ||||||
WBPaper00055090 | |||||||
WBPaper00062840 | |||||||
Method | Gene |