WormBase Tree Display for Gene: WBGene00019030

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WBGene00019030	SMap	S_parent	Sequence	F58B6
	Identity	Version	4
		Name	CGC_name	exc-6	Person_evidence	WBPerson1052
						WBPerson580
			Sequence_name	F58B6.2
			Molecular_name	F58B6.2
				F58B6.2.1
				CE46968
			Other_name	inft-1	Person_evidence	WBPerson314
						WBPerson3809
				tag-268
				CELE_F58B6.2	Accession_evidence	NDB	BX284603
			Public_name	exc-6
		DB_info	Database	AceView	gene	3C201
				WormQTL	gene	WBGene00019030
				WormFlux	gene	WBGene00019030
				NDB	locus_tag	CELE_F58B6.2
				Panther	gene	CAEEL\|WormBase=WBGene00019030\|UniProtKB=Q9TYU9
					family	PTHR45691
				NCBI	gene	175277
				RefSeq	protein	NM_064933.5
				SwissProt	UniProtAcc	Q9TYU9
				TREEFAM	TREEFAM_ID	TF338399
				UniProt_GCRP	UniProtAcc	Q9TYU9
		Species	Caenorhabditis elegans
		History	Version_change	1	28 May 2004 13:31:01	WBPerson1971	Event	Imported	Initial conversion from CDS class of stlace from WS125
				2	21 Jun 2005 09:45:25	WBPerson2970	Name_change	CGC_name	tag-268
				3	29 Jun 2006 14:05:41	WBPerson2970	Name_change	CGC_name	inft-1
								Other_name	tag-268
				4	04 Jul 2013 12:08:29	WBPerson2970	Event	Acquires_merge	WBGene00001367
							Name_change	CGC_name	exc-6
								Other_name	inft-1
			Acquires_merge	WBGene00001367
		Status	Live
	Gene_info	Biotype	SO:0001217
		Gene_class	exc
		Allele (336)
		Legacy_information	[Buechner M] exc for excretory canal defect. Canal varies in length from no outgrowth to almost complete outgrowth. Frequent small vacuoles and extra branchings in the canal lumen visible only by Nomarski microscopy. Animal is somewhat pale.
			[C.elegansII] rh103 : excretory canal defect. Canal varies in length from no outgrowth to almost complete outgrowth. Frequent small vacuoles and extrabranchings in the canal lumen visible only by Nomarski microscopy. Animal is somewhat pale. NA1,[NJ]
		Strain	WBStrain00028858
			WBStrain00036165
			WBStrain00008066
			WBStrain00008065
		RNASeq_FPKM (74)
		GO_annotation (15)
		Ortholog (38)
		Paralog	WBGene00000872	Caenorhabditis elegans	From_analysis	Panther
						WormBase-Compara
			WBGene00008848	Caenorhabditis elegans	From_analysis	WormBase-Compara
			WBGene00016735	Caenorhabditis elegans	From_analysis	WormBase-Compara
			WBGene00018976	Caenorhabditis elegans	From_analysis	WormBase-Compara
			WBGene00021473	Caenorhabditis elegans	From_analysis	WormBase-Compara
			WBGene00021698	Caenorhabditis elegans	From_analysis	WormBase-Compara
		Structured_description	Automated_description	Predicted to enable actin binding activity. Involved in epithelium development; regulation of microtubule polymerization; and regulation of tube size. Part of filamentous actin. Is an ortholog of human FHDC1 (FH2 domain containing 1).	Paper_evidence	WBPaper00065943
					Curator_confirmed	WBPerson324
						WBPerson37462
					Inferred_automatically	This description was generated automatically by a script based on data from the WS291 version of WormBase
					Date_last_updated	29 Nov 2023 00:00:00
	Molecular_info	Corresponding_CDS	F58B6.2
		Corresponding_CDS_history	F58B6.2:wp229
		Corresponding_transcript	F58B6.2.1
		Other_sequence (55)
		Associated_feature	WBsf658597
			WBsf717858
			WBsf991227
			WBsf991228
			WBsf991229
			WBsf991230
			WBsf1014181
	Experimental_info	RNAi_result (14)
		Expr_pattern	Expr3604
			Expr6251
			Expr12322
			Expr13058
			Expr14689
			Expr1013993
			Expr1038217
			Expr1152701
			Expr2011392
			Expr2029628
		Drives_construct	WBCnstr00004187
			WBCnstr00021177
			WBCnstr00038209
		Construct_product	WBCnstr00011529
			WBCnstr00020996
			WBCnstr00038209
			WBCnstr00041220
		Antibody	WBAntibody00002375
		Microarray_results (19)
		Expression_cluster	WBPaper00037950:A-class-motor-neurons_embryo_enriched
			WBPaper00037950:A-class-motor-neurons_embryo_SelectivelyEnriched
			WBPaper00037950:excretory-cell_larva_enriched
			WBPaper00037950:excretory-cell_larva_SelectivelyEnriched
			WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched
			WBPaper00037950:hypodermis_embryo_enriched
			WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
			WBPaper00044037:eat-2_upregulated
			WBPaper00044736:oscillating_dev_expression
			WBPaper00044857:BAR-1_upregulated
			WBPaper00045420:fertilization_downregulated_transcript
			WBPaper00045521:Gender_Neutral
			WBPaper00046012:tdp-1(ok803)_downregulated
			WBPaper00047131:daf-2(e1370)_upregulated_N2-background
			WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
			WBPaper00048988:daf-16(mu86)_upregulated_neuron
			WBPaper00048988:neuron_expressed
			WBPaper00049545:jmjd-3.1(+)_upregulated
			WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
			WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_downregulated
			WBPaper00049920:Glucose-Diet_upregulated_N2
			WBPaper00050015:ifg-1(RNAi)_upregulated
			WBPaper00050488:adult_vs_dauer_regulated_N2_20C
			WBPaper00050726:OsmoticStress_regulated_Food
			WBPaper00050726:OsmoticStress_regulated_NoFood
			WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
			WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
			WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
			WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
			WBPaper00050990:hypodermis_enriched
			WBPaper00050990:hypodermis_expressed
			WBPaper00051404:alg-1(gk214)_downregulated
			WBPaper00051558:fog-2(q71)_regulated
			WBPaper00053184:sma-2(rax5)_upregulated
			WBPaper00053184:sma-4(rax3)_upregulated
			WBPaper00053295:lin-22(ot269)_upregulated
			WBPaper00053302:stavudine_24h_regulated
			WBPaper00053302:stavudine_72h_regulated
			WBPaper00053302:zidovudine_72h_regulated
			WBPaper00053388:dauer_regulated_Cluster5
			WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
			WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
			WBPaper00054410:set-9(rw5)_downregulated
			WBPaper00054410:set-26(tm2467)_downregulated
			WBPaper00054493:hpl-2(tm1489)_upregulated
			WBPaper00054872:egl-9(sa307)_upregulated
			WBPaper00055013:hmg-3(bar24)_downregulated
			WBPaper00055013:hmg-4(RNAi)_downregulated
			WBPaper00055013:spt-16(RNAi)_downregulated
			WBPaper00055354:Metformin_upregulated
			WBPaper00055354:Rifampicin_upregulated
			WBPaper00055648:male-vas-deferens_expressed
			WBPaper00055648:spermatheca_expressed
			WBPaper00055827:pfd-6(gk493446)_downregulated
			WBPaper00055971:nhl-2(ok818)_20C_downregulated
			WBPaper00055971:nhl-2(ok818)_25C_upregulated
			WBPaper00056034:pals-22(jy3)_upregulated
			WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
			WBPaper00056161:male_enriched_siRNA
			WBPaper00056165:MINA-1_interacting_mRNA
			WBPaper00056443:sek-1(km4)_upregulated
			WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
			WBPaper00056619:CEPsh_enriched
			WBPaper00056809:smn-1(ok355)_downregulated
			WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
			WBPaper00057068:ints-4(RNAi)_downregulated
			WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
			WBPaper00057154:HeatShock_upregulated_mRNA
			WBPaper00058598:mex-1(or286)_upregulated
			WBPaper00058598:mex-3(eu149)_upregulated
			WBPaper00058598:sin-3(tm1276)_downregulated
			WBPaper00058598:spn-4(tm291)_upregulated
			WBPaper00058691:cfp-1(tm6369)_upregulated
			WBPaper00058691:set-2(bn129)_upregulated
			WBPaper00058691:sin-3(tm1276)_upregulated
			WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
			WBPaper00059421:daf-3(mgDf90)_downregulated
			WBPaper00059664:srbc-48(ac23)_upregulated
			WBPaper00059728:20ug_cholesterol_upregulated
			WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
			WBPaper00060100:SiNP_upregulated_mRNA
			WBPaper00060683:hlh-11(ko1)_upregulated
			WBPaper00060811:L1_vs_adult_downregulated_neural
			WBPaper00061007:HB101_upregulated
			WBPaper00061203:sin-3(tm1276)_upregulated
			WBPaper00061340:B
			WBPaper00061340:Excretory_cell
			WBPaper00061340:g1A
			WBPaper00061340:Parent_of_K_Kprime
			WBPaper00061340:Rectal_gland
			WBPaper00061340:Seam_cell
			WBPaper00061340:Y
			WBPaper00061479:hda-1(ne4752)_upregulated
			WBPaper00061479:ubc-9(ne4833)_upregulated
			WBPaper00061527:nep-16-C08G9.2
			WBPaper00061651:Spermatheca_enriched
			WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
			WBPaper00062156:jmjd-5(zr1234)_downregulated_germline
			WBPaper00062156:jmjd-5(zr1234)_upregulated
			WBPaper00062159:hda-2(ok1479)_upregulated
			WBPaper00062325:muscle_depleted_coding-RNA
			WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
			WBPaper00064005:starvation_downregulated_N2_mRNA
			WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
			WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
			WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
			WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
			WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
			WBPaper00064306:Agaro-oligosaccharides_upregulated
			WBPaper00064539:nhr-114(gk849)_downregulated
			WBPaper00064716:paraquat_upregulated
			WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
			WBPaper00065096:25C_vs_20C_downregulated
			WBPaper00065096:Day10_vs_Day1_downregulated
			WBPaper00065258:anchor-cell_enriched
			WBPaper00065746:eat-2(ad1113)_downregulated
			WBPaper00065835:Day5_vs_Day1_downregulated
			WBPaper00065841:11_0
			WBPaper00065841:13_1
			WBPaper00065841:31_0
			WBPaper00065841:43_0
			WBPaper00065841:57_0
			WBPaper00065841:57_1
			WBPaper00066110:Doxorubicin_upregulated_diploid
			WBPaper00066110:tetraploid_vs_diploid_upregulated
			cgc4386_cluster_6_5
			WBPaper00025141:N2_Expressed_Genes
			WBPaper00025141:unc-4::GFP_Enriched_Genes
			WBPaper00025141:unc-4::GFP_Expressed_Genes
			WBPaper00026929:sir-2.1_overexpression_regulated
			WBPaper00030839:Embryo_A_Class
			WBPaper00031003:24hr_muscle_depleted
			WBPaper00031003:total_muscle_depleted
			WBPaper00032165:A_to_C_transit_increased
			WBPaper00036286:Pattern_G
			WBPaper00040821:Au-NP_regulated
			WBPaper00040963:Q200_down
			WBPaper00041174:environmental
			WBPaper00041174:genotypic
			WBPaper00041174:genotypic_and_environmental
			WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
			WBPaper00045015:nhr-25(RNAi)_upregulated
			WBPaper00045263:nuo-6(qm200)_downregulated
			WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
		Interaction (17)
	Map_info	Map	III	Position	-22.7363	Error	0.234072
		Positive	Positive_clone	F58B6	Inferred_automatically	From sequence, transcript, pseudogene data
		Mapping_data	Multi_point	5299
				2076
				3280
				3291
			Pos_neg_data	8596
		Pseudo_map_position
	Reference (19)
	Remark	Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.	CGC_data_submission
	Method	Gene