WormBase Tree Display for Gene: WBGene00018645

WBGene00018645 SMap: S_parent: Sequence: F49F1
  Identity: Version: 1
    Name: Sequence_name: F49F1.5
      Molecular_name: F49F1.5a
        F49F1.5a.1
        CE17088
        F49F1.5b
        CE48537
        F49F1.5b.1
      Other_name: CELE_F49F1.5 Accession_evidence: NDB BX284604
      Public_name: F49F1.5
    DB_info: Database: AceView gene 4E884
        WormQTL gene WBGene00018645
        WormFlux gene WBGene00018645
        NDB locus_tag CELE_F49F1.5
        Panther gene CAEEL|WormBase=WBGene00018645|UniProtKB=Q9GZE4
          family PTHR21724
        NCBI gene 186062
        RefSeq protein NM_001307492.2
            NM_068085.7
        TrEMBL UniProtAcc U4PRI6
            Q9GZE4
        UniProt_GCRP UniProtAcc Q9GZE4
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (32)
    RNASeq_FPKM (74)
    Ortholog (17)
    Paralog (35)
    Structured_description: Automated_description: Enriched in OLL; PVD; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-one chemicals including Heme; hydrogen sulfide; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShK domain-like and ShKT domain. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F49F1.5a
      F49F1.5b
    Corresponding_transcript: F49F1.5a.1
      F49F1.5b.1
    Associated_feature: WBsf229945
  Experimental_info: RNAi_result: WBRNAi00047880 Inferred_automatically: RNAi_primary
      WBRNAi00087733 Inferred_automatically: RNAi_primary
      WBRNAi00032559 Inferred_automatically: RNAi_primary
      WBRNAi00015344 Inferred_automatically: RNAi_primary
      WBRNAi00103374 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023027
      Expr1151711
      Expr2003954
      Expr2022176
    Drives_construct: WBCnstr00026362
    Construct_product: WBCnstr00026362
    Microarray_results (17)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036231:long-telomeres_downregulated
      WBPaper00036738:500uM_Heme_upregulated
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_CoreEnriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040285:H2S_12hr_upregulated
      WBPaper00040560:hpl-2_embryo_upregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00042561:smgl-2(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00045316:prg-1_upregulated_L3
      WBPaper00045390:tunicamycin_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049920:hyl-2(tm2031)_upregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPA_upregulated
      WBPaper00050225:flp-6(RNAi)_upregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050561:indole_0.1mM-indole_upregulated
      WBPaper00050561:indole_10-fold_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051137:N.parisii-virus_upregulated_N2
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051437:Cit-SPIONs_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053154:human-amyloid-beta_tau_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053771:down_by_skn-1(RNAi)_at_24h-NaCl
      WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054872:egl-9(sa307)_upregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Psora_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056073:NHR-86_interacting_promoter
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:flcn-1(ok975)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058665:amino-functionized-graphene-oxide_upregulated_mRNA
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059373:stt-3(RNAi)_upregulated
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:CoCl2_6hr_upregulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060634:fhod-1(tm2363)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061081:skpo-1(ok1640)_upregulated_OP50
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:nhr-107_19485-nhr-109_3743
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061753:csr-1(tor159)_upregulated_20C
      WBPaper00061902:camt-1(ok515)_regulated_BAG
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00062587:lsl-1(ljm1)_downregulated
      WBPaper00062587:lsl-1(tm4769)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064532:pals-25(jy111)_upregulated
      WBPaper00064632:daf-2(e1370)_downregulated_intestine
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065926:pgph-2(overepxreesion)_upregulated
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00066093:E.coli-purE_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066118:cyclobutrifluram_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4386_cluster_1_3
      cgc4489_group_4
      WBPaper00026929:Resveratrol_regulated_N2
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00027111:rde-3(r459)_upregulated
      WBPaper00027722:Microbacterium_nematophilum_upregulated
      WBPaper00028789:PA14_vs_OP50_upregulated_4hr
      WBPaper00031003:hlh_1_enriched
      WBPaper00031703:heme_responsive_7
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:FedUp
      WBPaper00034661:AgNPs_downregulated
      WBPaper00034739:N2lessDR1350
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036286:Pattern_E
      WBPaper00036383:ash-2_L3_regulated
      WBPaper00037113:CPF_16C_up-regulated
      WBPaper00037113:DZN_16C_up-regulated
      WBPaper00037695:WC_5-day
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00039851:HK_C_albicans_vs_HK_OP50
      WBPaper00039851:Live_C_albicans_vs_HK_OP50
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00041609:hpl-1_hpl-2_upregulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045015:nhr-25(RNAi)_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053688:E.faecalis_downregulated
      WBPaper00053688:E.faecium_downregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:Cluster_C
      [cgc6390]:herm_soma-enriched
    Interaction: WBInteraction000351265
      WBInteraction000419064
  Map_info: Positive: Positive_clone: F49F1 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV -0.673562
  Reference: WBPaper00031805
    WBPaper00058665
  Method: Gene