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WormBase Tree Display for Gene: WBGene00017166

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Name Class

WBGene00017166SMapS_parentSequenceF01F1
IdentityVersion2
NameCGC_namealdo-2Person_evidenceWBPerson261
Sequence_nameF01F1.12
Molecular_nameF01F1.12
F01F1.12.1
CE01225
F01F1.12.2
Other_nameCELE_F01F1.12Accession_evidenceNDBBX284603
Public_namealdo-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
203 Aug 2009 11:56:38WBPerson9133Name_changeCGC_namealdo-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classaldo
Allele (29)
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (47)
ParalogWBGene00011474Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionaldo-2 encodes a fructose-bisphosphate aldolase homologous to human ALDOB, which when mutated leads to fructosemia, hereditary fructose intolerance (OMIM:229600).Paper_evidenceWBPaper00004637
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated09 Sep 2009 00:00:00
Automated_descriptionPredicted to enable fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to be located in cytosol. Predicted to be part of heterochromatin. Expressed in several structures, including hyp7 syncytium. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Is an ortholog of human ALDOC (aldolase, fructose-bisphosphate C).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:438Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:418)
Molecular_infoCorresponding_CDSF01F1.12
Corresponding_CDS_historyF01F1.12b:wp275
Corresponding_transcriptF01F1.12.1
F01F1.12.2
Other_sequence (568)
Associated_featureWBsf651081
WBsf666461
WBsf666462
WBsf666934
WBsf666935
WBsf981488
WBsf226734
WBsf226735
Experimental_infoRNAi_resultWBRNAi00006856Inferred_automaticallyRNAi_primary
WBRNAi00113973Inferred_automaticallyRNAi_primary
WBRNAi00024995Inferred_automaticallyRNAi_primary
WBRNAi00043743Inferred_automaticallyRNAi_primary
WBRNAi00008595Inferred_automaticallyRNAi_primary
WBRNAi00043744Inferred_automaticallyRNAi_primary
Expr_patternExpr125
Expr4048
Expr1018341
Expr1037380
Expr1147728
Expr2009286
Expr2027523
Drives_constructWBCnstr00027516
Construct_productWBCnstr00027516
Microarray_results (33)
Expression_cluster (227)
Interaction (67)
Map_infoMapIIIPosition-1.43798Error5.9e-05
PositivePositive_cloneF01F1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027145
WBPaper00028498
WBPaper00031648
WBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00056909
WBPaper00061616
WBPaper00063976
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene