WormBase Tree Display for Gene: WBGene00011474
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| WBGene00011474 | SMap | S_parent | Sequence | T05D4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | aldo-1 | Person_evidence | WBPerson261 | |||||
| Sequence_name | T05D4.1 | ||||||||
| Molecular_name | T05D4.1 | ||||||||
| T05D4.1.1 | |||||||||
| CE16341 | |||||||||
| Other_name | CELE_T05D4.1 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | aldo-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 03 Aug 2009 11:56:38 | WBPerson9133 | Name_change | CGC_name | aldo-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | aldo | ||||||||
| Allele (29) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (49) | |||||||||
| Paralog | WBGene00017166 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | aldo-1 is orthologous to the human gene ALDOLASE A, FRUCTOSE-BISPHOSPHATE (ALDOA; OMIM:103850), which when mutated leads to aldolase A deficiency. | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Sep 2009 00:00:00 | ||||||||
| Automated_description | Enables fructose-bisphosphate aldolase activity and identical protein binding activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in gonad; intestinal muscle; and spermathecal-uterine valve cell. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; hereditary fructose intolerance syndrome; and type 2 diabetes mellitus. Is an ortholog of human ALDOA (aldolase, fructose-bisphosphate A) and ALDOC (aldolase, fructose-bisphosphate C). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9869 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:417) | ||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:417) | ||||||
| DOID:438 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:418) | ||||||
| EFO:MONDO:0002412 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:414) | ||||||
| Molecular_info | Corresponding_CDS | T05D4.1 | |||||||
| Corresponding_transcript | T05D4.1.1 | ||||||||
| Other_sequence (281) | |||||||||
| Associated_feature (12) | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Chronogram1292 | ||||||||
| Expr6616 | |||||||||
| Expr9433 | |||||||||
| Expr12931 | |||||||||
| Expr13097 | |||||||||
| Expr1014729 | |||||||||
| Expr1035049 | |||||||||
| Expr1156129 | |||||||||
| Expr2009285 | |||||||||
| Expr2027522 | |||||||||
| Drives_construct | WBCnstr00003499 | ||||||||
| WBCnstr00030627 | |||||||||
| Construct_product | WBCnstr00013998 | ||||||||
| WBCnstr00030627 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (307) | |||||||||
| Interaction (64) | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | III | Position | 21.2674 | Error | 0.001447 | |||
| Positive | Positive_clone | T05D4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027145 | ||||||||
| WBPaper00028498 | |||||||||
| WBPaper00031648 | |||||||||
| WBPaper00038444 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060131 | |||||||||
| WBPaper00062237 | |||||||||
| WBPaper00062642 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
