WormBase Tree Display for Gene: WBGene00011474
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WBGene00011474 | SMap | S_parent | Sequence | T05D4 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | aldo | ||||||
Allele (29) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (21) | |||||||
Ortholog (49) | |||||||
Paralog | WBGene00017166 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
Structured_description | Concise_description | aldo-1 is orthologous to the human gene ALDOLASE A, FRUCTOSE-BISPHOSPHATE (ALDOA; OMIM:103850), which when mutated leads to aldolase A deficiency. | Paper_evidence | WBPaper00004637 | |||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 09 Sep 2009 00:00:00 | ||||||
Automated_description | Enables fructose-bisphosphate aldolase activity and identical protein binding activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in gonad; intestinal muscle; and spermathecal-uterine valve cell. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; hereditary fructose intolerance syndrome; and type 2 diabetes mellitus. Is an ortholog of human ALDOA (aldolase, fructose-bisphosphate A) and ALDOC (aldolase, fructose-bisphosphate C). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:9869 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:417) | ||
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:417) | ||||
DOID:438 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:418) | ||||
EFO:MONDO:0002412 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:414) | ||||
Molecular_info | Corresponding_CDS | T05D4.1 | |||||
Corresponding_transcript | T05D4.1.1 | ||||||
Other_sequence (281) | |||||||
Associated_feature (12) | |||||||
Experimental_info | RNAi_result (12) | ||||||
Expr_pattern | Chronogram1292 | ||||||
Expr6616 | |||||||
Expr9433 | |||||||
Expr12931 | |||||||
Expr13097 | |||||||
Expr1014729 | |||||||
Expr1035049 | |||||||
Expr1156129 | |||||||
Expr2009285 | |||||||
Expr2027522 | |||||||
Drives_construct | WBCnstr00003499 | ||||||
WBCnstr00030627 | |||||||
Construct_product | WBCnstr00013998 | ||||||
WBCnstr00030627 | |||||||
Microarray_results (21) | |||||||
Expression_cluster (307) | |||||||
Interaction (64) | |||||||
WBProcess | WBbiopr:00000001 | ||||||
Map_info | Map | III | Position | 21.2674 | Error | 0.001447 | |
Positive | Positive_clone | T05D4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00027145 | ||||||
WBPaper00028498 | |||||||
WBPaper00031648 | |||||||
WBPaper00038444 | |||||||
WBPaper00038491 | |||||||
WBPaper00049828 | |||||||
WBPaper00055090 | |||||||
WBPaper00060131 | |||||||
WBPaper00062237 | |||||||
WBPaper00062642 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |