WormBase Tree Display for Gene: WBGene00017166

WBGene00017166 SMap: S_parent: Sequence: F01F1
  Identity: Version: 2
    Name: CGC_name: aldo-2 Person_evidence: WBPerson261
      Sequence_name: F01F1.12
      Molecular_name: F01F1.12
        F01F1.12.1
        CE01225
        F01F1.12.2
      Other_name: CELE_F01F1.12 Accession_evidence: NDB BX284603
      Public_name: aldo-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 03 Aug 2009 11:56:38 WBPerson9133 Name_change: CGC_name: aldo-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aldo
    Allele (29)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog: WBGene00030727 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00055563 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00163286 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00215847 Caenorhabditis japonica From_analysis: TreeFam
            WormBase-Compara
      WBGene00129730 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00223396 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5083 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g5038 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g14021 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g3214 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g24068 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g12862 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g62 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g1465 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g21831 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00417.g10556 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_17846.g25818 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-aldo-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold546.g3481 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_02617.g27251 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_19839 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_010649 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g09609 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g10529 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30141900 Caenorhabditis inopinata From_analysis: WormBase-Compara
      Sp34_30280200 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7814 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244689 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00276380 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00262280 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00295439 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0000064 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0039425 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-383 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-030131-8369 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-030821-1 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-040426-2299 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-050706-128 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:418 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      MGI:87994 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      MGI:101863 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1931052 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      MGI:87995 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      MGI:2447811 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      RGD:2089 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      RGD:2091 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1359133 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
            PhylomeDB
    Paralog: WBGene00011474 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: aldo-2 encodes a fructose-bisphosphate aldolase homologous to human ALDOB, which when mutated leads to fructosemia, hereditary fructose intolerance (OMIM:229600). Paper_evidence: WBPaper00004637
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 09 Sep 2009 00:00:00
      Automated_description: Predicted to enable fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to be located in cytosol. Predicted to be part of heterochromatin. Expressed in several structures, including hyp7 syncytium. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Is an ortholog of human ALDOC (aldolase, fructose-bisphosphate C). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:438 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:418)
  Molecular_info: Corresponding_CDS: F01F1.12
    Corresponding_CDS_history: F01F1.12b:wp275
    Corresponding_transcript: F01F1.12.1
      F01F1.12.2
    Other_sequence (568)
    Associated_feature: WBsf651081
      WBsf666461
      WBsf666462
      WBsf666934
      WBsf666935
      WBsf981488
      WBsf226734
      WBsf226735
  Experimental_info: RNAi_result: WBRNAi00006856 Inferred_automatically: RNAi_primary
      WBRNAi00113973 Inferred_automatically: RNAi_primary
      WBRNAi00024995 Inferred_automatically: RNAi_primary
      WBRNAi00043743 Inferred_automatically: RNAi_primary
      WBRNAi00008595 Inferred_automatically: RNAi_primary
      WBRNAi00043744 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr125
      Expr4048
      Expr1018341
      Expr1037380
      Expr1147728
      Expr2009286
      Expr2027523
    Drives_construct: WBCnstr00027516
    Construct_product: WBCnstr00027516
    Microarray_results (33)
    Expression_cluster (227)
    Interaction (67)
  Map_info: Map: III Position: -1.43798 Error: 5.9e-05
    Positive: Positive_clone: F01F1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027145
    WBPaper00028498
    WBPaper00031648
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00056909
    WBPaper00061616
    WBPaper00063976
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene