WormBase Tree Display for Gene: WBGene00015464

WBGene00015464 SMap: S_parent: Sequence: C05C8
  Identity: Version: 2
    Name: Sequence_name: C05C8.7
      Molecular_name: C05C8.7
        C05C8.7.1
        CE07925
      Other_name: phi-49 Person_evidence: WBPerson2582
        CELE_C05C8.7 Accession_evidence: NDB BX284605
      Public_name: C05C8.7
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 17 Mar 2005 13:54:35 WBPerson2970 Name_change: Other_name: phi-49
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (53)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (41)
    Paralog: WBGene00014013 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable mannose-6-phosphate isomerase activity. Predicted to be involved in GDP-mannose biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ib. Is an ortholog of human MPI (mannose phosphate isomerase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:2978 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7216)
      DOID:0080554 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7216)
  Molecular_info: Corresponding_CDS: C05C8.7
    Corresponding_transcript: C05C8.7.1
    Other_sequence (21)
    Associated_feature: WBsf652767
      WBsf652768
      WBsf652769
      WBsf669114
      WBsf1000456
      WBsf1019908
      WBsf233932
      WBsf233933
      WBsf233934
  Experimental_info: RNAi_result (11)
    Expr_pattern: Chronogram1184
      Expr5164
      Expr1018201
      Expr1036610
      Expr1143811
      Expr2000454
      Expr2018677
    Drives_construct: WBCnstr00004089
      WBCnstr00028827
    Construct_product: WBCnstr00028827
    Microarray_results (26)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037682:sma-2_sma-4_upregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_CoreEnriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042477:rsr-2(RNAi)_upregulated_RNAseq
      WBPaper00043945:MeHg_upregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045861:ash-2(tm1095)_downregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_downregulated_protein
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:hyl-2(tm2031)_downregulated
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPA_downregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051265:F1_hrde-1(tm1200)_downregulated
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:G2_and_W_blasts
      WBPaper00061340:hyp4_hyp5_hyp6
      WBPaper00061340:hyp7_AB_lineage
      WBPaper00061340:hyp7_C_lineage
      WBPaper00061340:P_cell
      WBPaper00061340:Seam_cell
      WBPaper00061340:T
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:lon-8-C18D11.1_11630
      WBPaper00061527:tnt-4-myo-1_2160
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062184:PA14_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062456:doxycycline_upregulated_CB4856_protein
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
      WBPaper00065272:dhgd-1(tm6671)_downregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:0_0
      WBPaper00065841:64_0
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_4_6
      cgc4489_group_8
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00034739:N2lessDR1350
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00040184:hcf-1nc_sir-2.1up_daf-2up
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045865:biofilm_downregulated_B
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      [cgc5376]:let-60(G12V)-regulated_genes
      [cgc6390]:Cluster_B
      [cgc6390]:herm_soma-enriched
    Interaction: WBInteraction000036059
      WBInteraction000037154
      WBInteraction000040598
      WBInteraction000041537
      WBInteraction000043636
      WBInteraction000046481
      WBInteraction000046608
      WBInteraction000048354
      WBInteraction000048375
      WBInteraction000049159
      WBInteraction000049165
      WBInteraction000050334
      WBInteraction000136080
      WBInteraction000176522
      WBInteraction000214422
      WBInteraction000222623
      WBInteraction000225895
      WBInteraction000239011
      WBInteraction000248094
      WBInteraction000251788
      WBInteraction000271042
      WBInteraction000317684
      WBInteraction000321610
      WBInteraction000326295
      WBInteraction000337097
      WBInteraction000343177
      WBInteraction000360114
      WBInteraction000361382
      WBInteraction000368525
      WBInteraction000368776
      WBInteraction000410444
      WBInteraction000411546
      WBInteraction000414956
      WBInteraction000433335
      WBInteraction000448387
      WBInteraction000450162
      WBInteraction000450707
      WBInteraction000452074
      WBInteraction000457193
      WBInteraction000457824
      WBInteraction000521046
      WBInteraction000539912
      WBInteraction000548230
      WBInteraction000550965
      WBInteraction000578736
      WBInteraction000579652
      WBInteraction000584372
  Map_info: Positive: Positive_clone: C05C8 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: V 0.646078
  Reference: WBPaper00029024
    WBPaper00032078
    WBPaper00038491
    WBPaper00055090
  Method: Gene