WormBase Tree Display for Gene: WBGene00013869

WBGene00013869 SMap: S_parent: Sequence: ZC373
  Identity: Version: 2
    Name: CGC_name: mlck-1 Person_evidence: WBPerson1777
      Sequence_name: ZC373.4
      Molecular_name: ZC373.4
        ZC373.4.1
        CE02377
      Other_name: CELE_ZC373.4 Accession_evidence: NDB BX284606
      Public_name: mlck-1
    DB_info: Database: AceView gene XK682
        WormQTL gene WBGene00013869
        SignaLink protein WBGene00013869
        WormFlux gene WBGene00013869
        NDB locus_tag CELE_ZC373.4
        Panther gene CAEEL|WormBase=WBGene00013869|UniProtKB=Q23260
          family PTHR24347
        NCBI gene 181217
        RefSeq protein NM_077288.7
        TrEMBL UniProtAcc Q23260
        UniProt_GCRP UniProtAcc Q23260
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 05 Jan 2017 11:44:00 WBPerson2970 Name_change: CGC_name: mlck-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mlck
    Allele (102)
    RNASeq_FPKM (74)
    GO_annotation: 00077792
      00077793
      00077794
      00077795
      00077796
      00077797
      00077798
      00120611
      00120612
      00120613
    Ortholog (37)
    Paralog: WBGene00000553 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00003400 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00006436 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00009326 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00019911 Caenorhabditis elegans From_analysis: TreeFam
            Panther
    Structured_description: Automated_description: Predicted to enable myosin light chain kinase activity. Predicted to be involved in phosphorylation. Expressed in anal sphincter muscle; hermaphrodite gonad; pharynx; and vulval cell. Is an ortholog of human MYLK4 (myosin light chain kinase family member 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZC373.4
    Corresponding_transcript: ZC373.4.1
    Other_sequence: CJC10793_1
      MCC02797_1
      Name_isotig01340
      JI164587.1
      MC03019
    Associated_feature: WBsf718686
      WBsf1006597
      WBsf1006598
      WBsf1023656
  Experimental_info: RNAi_result: WBRNAi00002343 Inferred_automatically: RNAi_primary
      WBRNAi00113725 Inferred_automatically: RNAi_primary
      WBRNAi00058848 Inferred_automatically: RNAi_primary
      WBRNAi00113729 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr13845
      Expr13846
      Expr1012097
      Expr1036203
      Expr1162292
      Expr2013597
      Expr2031830
    Drives_construct: WBCnstr00029489
      WBCnstr00040202
    Construct_product: WBCnstr00029489
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:Cluster_3
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032976:dosage_compensated_genes
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00044037:eat-2_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045521:Gender_Neutral
      WBPaper00046121:mesoderm_unique
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:HB101_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:gtl-1-hum-8_16432
      WBPaper00061527:kin-29_2839-unc-9_3883
      WBPaper00061651:ALM_enriched
      WBPaper00061651:AVM_enriched
      WBPaper00061651:PLM_enriched
      WBPaper00061651:Spermatheca_enriched
      WBPaper00061753:csr-1(tor159)_downregulated_20C
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065841:4_0
      WBPaper00065841:4_1
      WBPaper00065841:7_0
      WBPaper00065841:7_1
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:11_1
      WBPaper00065841:11_2
      WBPaper00065841:20_0
      WBPaper00065841:20_1
      WBPaper00065841:20_2
      WBPaper00065841:38_1
      WBPaper00065841:38_2
      WBPaper00065841:43_0
      WBPaper00065841:54_0
      WBPaper00065841:102_0
      WBPaper00065841:143_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00036286:Pattern_D
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
    Interaction (13)
  Map_info: Map: X Position: 1.73592
    Positive: Positive_clone: ZC373 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027258
    WBPaper00030971
    WBPaper00038491
    WBPaper00052003
    WBPaper00054992
    WBPaper00055090
    WBPaper00057748
    WBPaper00066328
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene