WormBase Tree Display for Gene: WBGene00013847

WBGene00013847 SMap: S_parent: Sequence: ZC84
  Identity: Version: 2
    Name: CGC_name: cls-3 Person_evidence: WBPerson534
            WBPerson283
      Sequence_name: ZC84.3
      Molecular_name: ZC84.3
        ZC84.3.1
        CE43505
      Other_name: CELE_ZC84.3 Accession_evidence: NDB BX284603
      Public_name: cls-3
    DB_info: Database: AceView gene 3K276
        WormQTL gene WBGene00013847
        WormFlux gene WBGene00013847
        NDB locus_tag CELE_ZC84.3
        Panther gene CAEEL|WormBase=WBGene00013847|UniProtKB=Q03609
          family PTHR21567
        NCBI gene 176298
        RefSeq protein NM_001392172.1
        SwissProt UniProtAcc Q03609
        TREEFAM TREEFAM_ID TF101155
        UniProt_GCRP UniProtAcc Q03609
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 21 Jun 2010 10:25:58 WBPerson2970 Name_change: CGC_name: cls-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cls
    Allele (51)
    Strain: WBStrain00033123
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (39)
    Paralog: WBGene00000491 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000549 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00015580 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable microtubule binding activity. Involved in astral microtubule organization and establishment of mitotic spindle localization. Predicted to be located in basal cortex; kinetochore; and microtubule cytoskeleton. Expressed in neurons and pharyngeal gland cell. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZC84.3
    Corresponding_CDS_history: ZC84.3:wp200
    Corresponding_transcript: ZC84.3.1
    Other_sequence: CBC17725_1
    Associated_feature: WBsf651343
      WBsf655466
      WBsf667245
      WBsf227255
  Experimental_info: RNAi_result: WBRNAi00006060 Inferred_automatically: RNAi_primary
      WBRNAi00073423 Inferred_automatically: RNAi_primary
      WBRNAi00080603 Inferred_automatically: RNAi_primary
      WBRNAi00021762 Inferred_automatically: RNAi_primary
      WBRNAi00038105 Inferred_automatically: RNAi_primary
      WBRNAi00000349 Inferred_automatically: RNAi_primary
      WBRNAi00059026 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr25
      Expr1020086
      Expr1036190
      Expr1162456
      Expr2010254
      Expr2028496
    Drives_construct: WBCnstr00029507
    Construct_product: WBCnstr00029507
    Antibody: WBAntibody00002343
    Microarray_results (19)
    Expression_cluster: WBPaper00024505:pharyngeal_enriched
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037946:LIN-39_interacting
      WBPaper00044037:eat-2_downregulated
      WBPaper00044037:eat-2_regulated_nhr-62_dependent
      WBPaper00044736:flat_dev_expression
      WBPaper00045303:ZK1236.1(tm4178)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045861:set-2(ok952)_upregulated
      WBPaper00045861:wdr-5(ok1417)_upregulated
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:csr-1(RNAi)_downregulated_Set1
      WBPaper00046805:csr-1(RNAi)_downregulated_Set2
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050094:glp-1(gf)_upregulated
      WBPaper00050094:mes-2(bn11)_upregulated
      WBPaper00050094:mes-6(bn66)_upregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051265:F1_morc-1(tm6048)_upregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051305:vit-2(ac3)_upregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053321:mes-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:mes-4(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054410:set-9(rw5)_upregulated
      WBPaper00054410:set-26(tm2467)_upregulated
      WBPaper00055103:thoc-5(wy822)_upregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056039:ptl-1(ok621)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:hpx-2(dg047)_upregulated_E.Coli
      WBPaper00056090:hpx-2(dg047)_upregulated_E.faecalis
      WBPaper00056165:mina-1(ok1521)_upregulated_transcript
      WBPaper00056167:Cry5B_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:flcn-1(ok975)_upregulated
      WBPaper00056731:human-amylin_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056855:his-72(uge40)_upregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057140:pptr-1(tm3103)_upregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060634:unc-120(st364)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061340:AIN_parent
      WBPaper00061340:ALM_BDU
      WBPaper00061340:ALM_PLM
      WBPaper00061340:ALN
      WBPaper00061340:AVE
      WBPaper00061340:DB
      WBPaper00061340:Neuroblast_ALM_BDU
      WBPaper00061340:RIC
      WBPaper00061340:RMD
      WBPaper00061340:SMB
      WBPaper00061340:XXX
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061478:pie-1(ne4303)_upregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hda-1(ne4747)_upregulated
      WBPaper00061527:utx-1_2886-swan-1_2192
      WBPaper00061651:ALM_enriched
      WBPaper00061651:DB_enriched
      WBPaper00061651:PDB_enriched
      WBPaper00061651:PLM_enriched
      WBPaper00061653:alh-4(hj221)_upregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00062103:neuron_enriched
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062446:nhr-8(ok186)_upregulated
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_PGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064716:paraquat_upregulated
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064789:Day12_vs_Day1_upregulated_neuron
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00065043:dcap-1(tm3163)_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065149:lin-52(n771)_upregulated
      WBPaper00065578:gcn-1(nc40)_downregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065841:19_0
      WBPaper00065841:20_0
      WBPaper00065841:20_2
      WBPaper00065841:54_0
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      cgc4386_cluster_5_1
      cgc4489_group_21
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00029437:dcr-1_downregulated
      WBPaper00030839:Embryo_A_Class
      WBPaper00030839:Larval_A_Class
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036286:Pattern_F
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00040426:CYD-1_CDK-4_upregulated
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00040858:eQTL_regulated_old
      WBPaper00041002:HF_3d_0.2mM_Down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041876:daf-10(m79)_upreglated
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_3h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00042234:xpa-1_upregulated
      WBPaper00042258:DA1877_downregulated_GravidAdult
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(23_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_A
    Interaction (14)
  Map_info: Map: III Position: 0.306499 Error: 0.009162
    Positive: Positive_clone: ZC84 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00041121
    WBPaper00045213
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene